F(ab’)₂-Fragments of Antirabic Immunoglobulin Production Using Immobilized Pepsin

Biotechnological scheme for F(ab')2-fragments of anti-rabies immunoglobulin production using immobilized pepsin was developed. Optimal ways for immobilized pepsin production were determined, conditions for fermentative hydrolysis of anti-rabies immunoglobulin were sorted out. Protective properties of F(ab')2-fragments of anti-rabies immunoglobulin produced by means of this method were assessed