ЦИТОРЕДУКТИВНОЕ ХИРУРГИЧЕСКОЕ ЛЕЧЕНИЕ С ИНТРАОПЕРАЦИОННОЙ ФОТОДИНАМИЧЕСКОЙ ТЕРАПИЕЙ БОЛЬНОЙ С МУЦИНОЗНЫМ КАНЦЕРОМАТОЗОМ БРЮШИНЫ

Clinical observation of a patient with an orphan disease (mucinous peritoneal carcinomatosis) after 2 courses of intraoperative photodynamic therapy with photogem photosensitizer is presented. During the first course of photodynamic therapy, photogem was administered at a dose of 2.5 mg/kg, the energy density of the laser radiation was 10 J/cm2. The duration of stabilization after the first course of treatment was 2 years, after which the progression of the disease was registered. The second course of photodynamic therapy was carried out in the same way. The duration of stabilization after the first course of treatment was 2.5 years. The patient died as a result of an accident unrelated to the disease.Приведено клиническое наблюдение за пациенткой с орфанным заболеванием – муцинозным канцероматозом брюшины – после проведения 2 курсов интраоперационной фотодинамической терапии с фотосенсибилизатором фотогем. При проведении первого курса фотодинамической терапии фотогем вводили в дозе 2,5 мг/кг, плотность энергии лазерного излучения составила 10 Дж/см2. Продолжительность стабилизации после первого курса лечения – 2 года, после чего зарегистрировано прогрессирование заболевания. Второй курс фотодинамической терапии проводили в том же режиме. Продолжительность стабилизации после второго курса лечения – 2,5 года. Пациентка погибла в результате несчастного случая, не связанного с заболеванием

CYTOREDUCTIVE SURGICAL TREATMENT WITH INTRAOPERATIVE PHOTODYNAMIC THERAPY IN PATIENTS WITH MUCINOUS PERITONEAL CARCINOMATOSIS

Clinical observation of a patient with an orphan disease (mucinous peritoneal carcinomatosis) after 2 courses of intraoperative photodynamic therapy with photogem photosensitizer is presented. During the first course of photodynamic therapy, photogem was administered at a dose of 2.5 mg/kg, the energy density of the laser radiation was 10 J/cm2. The duration of stabilization after the first course of treatment was 2 years, after which the progression of the disease was registered. The second course of photodynamic therapy was carried out in the same way. The duration of stabilization after the first course of treatment was 2.5 years. The patient died as a result of an accident unrelated to the disease