Reflection of Yakutia History in Siberian Lights Journal in 1920—1980

The article traces the dynamics of representations of the historical past of Yakutia in the publications of the monthly literary, artistic and socio-political magazine “Siberian Lights”. This issue is considered in the context of the processes of constructing the Soviet policy of memory throughout the entire period of the existence of the USSR. The relevance of the study is due to the increased attention to the specifics of historical knowledge presented in the public space, to its structures, interpretations and use for political and ideological purposes in the past and present. The novelty of the study is seen in the fact that until now the history of journal representations of the past of Yakutia in the context of state policy has not become the subject of independent scientific research. The study made it possible to identify the contexts that determined the specifics of creating journal representations of the history of Yakutia. The author established and characterized five stages of this representation. It is shown how the meanings and techniques of the politics of memory that were behind the approaches to the description and characteristics of the past of Yakutia changed. It is proved that the differences between approaches to representations were determined by the tendencies of strengthening and weakening the political and ideological control of the state in the field of memory politics and nation building

History and Traditional Culture of Altai in Context of the Historical Policy of Soviet State of 1920s-1940s: based on the materials of “Siberian Lights” Magazine

The dynamics of the memory policy aimed at forming in the historical memory of the readership of the Siberian Lights Magazine of the 1920s-1940s ideas about the historical past and traditional culture of Altai people is traced in the article. The relevance of the study is due to the growing attention to the features of historical knowledge in the public space, its structuring, the means of conceptual interpretation and the use in the processes of political self-regulation of society at various stages of development. The novelty of the research is seen in the fact that the history of the state policy of memory in relation to the past of Gorny Altai in its substantive and procedural aspects has not yet become the subject of independent scientific research. The contexts and conditions of creating journal representations of the historical past of Gorny Altai are revealed. The list of the authors covering this topic is characterized, as well as the factors that influenced the creation of journal representations of the history of the Altai people. The stages of this representation are established and characterized. It is shown how the memory policy techniques used by the authors of this journal at different stages changed. It is proved that at the stage of the 1920s, the Siberian Lights served as a platform for polemics of historians and subjects of regional politics, relatively independent in relation to the central government. At the second stage of the 1930s - 1940s, the authors of the journal were included, first of all, in the process of implementing the policy of memory of the central authorities

Politics of memory: historical symbols and commemorative practices in the system of socio-political selfregulation of the region (Siberia of the XX – early XXI centuries)

The purpose of this article is to generalize the dynamics of developing politics of memory, which was reflected in the processes of socio-political self-regulation of the Siberian region during the XX in the early XXI centuries. The study solves the problem of identifying the basic institutionalized forms and methods of using historical symbols within the framework of public commemorative practices and typical historical narratives, being established in Siberia in the XX beginning of the XXI centuries. The tasks also include identifying the stages of history of diverse manifestations of politics of memory in the memorial culture of Siberia in this period. The relevance of this article is due to the need of studying the meaning and methods of using historical symbols and commemorations within the framework of the politics of memory in order to form a critical, scientifically based position in relation to it. The study was implemented within the framework of the Memory Studies problem field and relies on interdisciplinary, sociocultural and socio-constructivist approaches. Comparative, diachronic, and systemic genetic methods there were used. For the first time the authors of the project intend to consider the politics of memory in relation to Siberia as a system that has gradually been formed and transformed depending on various conditions and factors. The scientific significance of the project is that the politics of memory implemented in the region by means of historical symbols and commemorative practices will be studied as a complex sociocultural phenomenon of regulating social consciousness of the regional society. As a result of the project implementation, the dynamics of using historical symbols and commemorations by various actors of regional politics in the sphere of building relations with central authorities and internal regional socio-political self-regulation processes. The authors define the stages of history of diverse manifestations of the memory policy in the memorial culture of Siberia. The Siberian macro-region, in spite of certain ethnocultural features in the areas where local peoples are densely populated, has emerged as one of the most Russian-oriented in its culture and dominant socio-political identity. And the basis of this result was the aggregate symbolic self-regulation of the Siberian society, which includes the dialectically complementary national and regional levels of memory policy

History of Cities in Western Siberia in Representations of Journal “Siberian Lights”: Political and Historical Contexts of 1920s — 1940s

Changes in the representation of the history of cities in Western Siberia in the journal “Siberian Lights” in the period from the beginning of the 20s to the mid 40s of the XX century are considered. These changes are interpreted by analyzing the general contexts of the development of historical local lore in Siberia and the activities of various subjects of the memory policy at both local and state levels. The relevance of the study is due to the increased interest on the part of society and the state in the problems of forming the historical memory of Russians about the national and regional past as one of the foundations of social identities. The novelty of the research is seen in the fact that until now the Siberian magazine periodicals of the Soviet era, in particular, “Siberian Lights”, are poorly understood as one of the significant means of forming the historical memory of society about the past of Western Siberia. The composition of the authors of materials on the history of Western Siberian cities is described in the article. The stages of the development of the history representation of West Siberian cities in the publications of the journal are determined, reflecting various, ideologically determined assessments of the historical past of the cities of Western Siberia. It is proved that during the Great Patriotic War, authors of works on the history of Western Siberian cities synthesized both the experience of Siberian ethnographers and their antagonists, pursuing the task of stimulating patriotic upsurge and the necessary social mobilization

Publications of Altai Fairy Tales and Heroic Legends in Context of Construction of 1920—1980s Soviet Politics of Memory

The issue of Altai fairy tales and heroic legends in the context of the 1920—1980s Soviet politics of memory is considered. Attention is paid to the participation of carriers of folklore traditions, folklorists, translators, writers, poets and editors in the creation of collections of Altai fairy tales. The specificity of their activities at different historical stages is characterized. The relevance of the study is due to the growing scientific and public interest in oral folk art in connection with the formation and development of the cultural memory of the peoples of Russia as the basis of social identities. The novelty of the research is seen in the fact that the publication of editions of Altai folk tales and heroic legends, collected, processed and published in Soviet times, is considered as a means of forming the cultural memory of Altai and other peoples of our country about the historical past of Altai Mountains. The authors note that Altai fairy tales, the publications of which have experienced a serious impact of the state politics of memory, have become the property of book culture rather than a living tradition of oral folk art. It is shown that in the late Soviet and early post-Soviet periods, book editions of fairy tales in the mass consciousness began to be perceived as a significant source for the interpretation of the historical past of the Altai ethnos

Elimination of the consequences of emergency events of natural and man-general character

The article discusses the features of the work of civil defense in the elimination of the consequences of emergency events on the example of Fukushima-1.В статье рассмотрены особенности работы гражданской обороны при ликвидации последствий чрезвычайных событий на примере Фукусимы-

The first and only combination of basal and prandial insulin analogs degludec and aspart: the position of Russian endocrinologists

Insulin therapy for diabetes mellitus is the most effective way to control glycemia with the progression of the disease and the ineffectiveness of other sugar-lowering drugs. At the same time, the existing limitations of traditional insulin preparations, along with increasing attention to the individualized treatment of this disease, are pushing developers to create drugs that most closely reproduce the effect of natural human insulin. In this regard, the appearance of a combination of insulin analogs, the action profile of which practically imitates insulin secretion by a healthy pancreas, presents new possibilities in the treatment of diabetes mellitus. Insulin degludec / insulin aspart (IDegAsp, Ryzodeg®, Novo Nordisk, Denmark) is the first and only soluble combination preparation containing 70% of the ultra-long-acting insulin analogue degludec and 30% of the ultra-short-acting insulin analogue aspart in one injection, which meets the need for both basal and prandial insulin. The combined drug has nothing in common with traditional mixed insulin preparations (both human and analog) and provides doctors and patients with significant advantages over the latter. The article presents the position of Russian experts-diabetologists with extensive experience in the use of IDegAsp regarding the role and place of the drug in real clinical practice. Data from real clinical practice confirm that IDegAsp is a reasonable choice for starting and intensifying insulin therapy for type 2 diabetes mellitus when basal and prandial glycemic control is required. The use of the drug is most appropriate in patients who are on basal, biphasic, basal-plus/basal-bolus regimens and who do not achieve the goals of glycemic control during prior therapy. One of the leading reasons for choosing IDegAsp may also be a lower risk of developing hypoglycemia compared to insulin analogues of previous generations — biphasic insulin aspart and basal insulin glargine 100 U/ml. In addition, IDegAsp is a simple, flexible and safe insulin therapy for patients on premix therapy and basal-plus/basis-bolus regimens who require basal and prandial glycemic control. IDegAsp is a simple, flexible and safe insulin therapy. The greatest benefit of this drug use can be obtained by patients for whom adherence to a complex therapy regimen is difficult (the elderly, with cognitive impairment, after a stroke, with dementia), as well as patients who have an active lifestyle, accompanied by irregular food intake. It is important to note that since January 1, 2021, there is no need for a decision by a special medical commission to prescribe (IDegAsp) Ryzodeg®. This fact, as well as a significant price reduction at the end of 2020, opens up broader prospects for using the drug in the routine practice of a Russian endocrinologist

ANTIBODIES TO BENZO[A]PYRENE IN SERUM OF PATIENTS WITH NON-SMALL CELL LUNG CANCER

The features of immune response to chemical carcinogen benzo[a]pyrene (Bp) at the patients with non-small cell lung cancer (NSCLC) are investigated. The isotypical distinctions in formation of antibodies (Ab) to Bp at the men with NSCLC in comparison with healthy are revealed. There were more often observed the high levels of IgG Ab-Bp at the men with NSCLC. Thus risk of occurrence NSCLC grows almost in 2 times at high levels of Ab-Bp of a class G

Approbation of a prognostic model of commodity turnover of a pharmacy organization on the example of the Sysert urban district

The purpose of the study is to test the predictive model of the turnover of a pharmacy organization on the example of the Sysert urban district.Цель исследования – апробация прогностической модели товарооборота аптечной организации на примере Сысертского городского округа

Diagnostics and treatment challenges of Ph-like acute lymphoblastic leukemia: a description of 3 clinical cases

B-cell acute lymphoblastic leukemia (B-ALL) is a diverse group of malignant blood disorders both with regard to the biological properties of the tumor and to therapeutic approaches. Immunophenotyping, molecular genetic techniques, whole-genome sequencing characterize B-ALL as a very diverse group for sensitivity to chemotherapy and prognosis. We present three clinical cases of patients with B-ALL and expected good response to standard therapy, in whom standard protocol treatment failured: refractoriness, persistence of minimal residual disease (MRD), and progression (MRD increase). The remission in these patients was achieved after chemotherapy change to immunological targeted therapy. Nowadays a unified therapeutic approach to all primary patients of the B-ALL is considered generally outdated. Great efforts are carrying out to develop molecular genetic classifications. The molecular dissection of subtypes of B-ALL goes on, and new protocols for selective treatment with targeting are clearly outlined for each subtype of B-ALL