79 research outputs found
Natural and Synthetic Polymers as Inhibitors of Drug Efflux Pumps
Inhibition of efflux pumps is an emerging approach in cancer therapy and drug delivery. Since it has been discovered that polymeric pharmaceutical excipients such as Tweens® or Pluronics® can inhibit efflux pumps, various other polymers have been investigated regarding their potential efflux pump inhibitory activity. Among them are polysaccharides, polyethylene glycols and derivatives, amphiphilic block copolymers, dendrimers and thiolated polymers. In the current review article, natural and synthetic polymers that are capable of inhibiting efflux pumps as well as their application in cancer therapy and drug delivery are discussed
Características individuais associadas à autopercepção da extensão territorial da vizinhança
Self-rated health in urban adults, perceptions of the physical and social environment, and reported comorbidities: The BH Health Study
Social context of neighborhood and socioeconomic status on leisure-time physical activity in a Brazilian urban center: The BH Health Study
Associação espacial entre variáveis socioeconômicas e risco relativo de nascimentos pré-termo na Região Metropolitana de São Paulo (RMSP) e na Área Metropolitana de Lisboa (AML)
Cremophor EL stimulates mitotic recombination in uvsH//uvsH diploid strain of Aspergillus nidulans
Disaggregating health inequalities within Rio de Janeiro, Brazil, 2002-2010, by applying an urban health inequality index
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