1,039 research outputs found
The role of electron-electron scattering in spin transport
We investigate spin transport in quasi 2DEG formed by III-V semiconductor
heterojunctions using the Monte Carlo method. The results obtained with and
without electron-electron scattering are compared and appreciable difference
between the two is found. The electron-electron scattering leads to suppression
of Dyakonov-Perel mechanism (DP) and enhancement of Elliott-Yafet mechanism
(EY). Finally, spin transport in InSb and GaAs heterostructures is investigated
considering both DP and EY mechanisms. While DP mechanism dominates spin
decoherence in GaAs, EY mechanism is found to dominate in high mobility InSb.
Our simulations predict a lower spin relaxation/decoherence rate in wide gap
semiconductors which is desirable for spin transport.Comment: to appear in Journal of Applied Physic
Crew Scheduling for Netherlands Railways: "destination: customer"
: In this paper we describe the use of a set covering model with additional constraints for scheduling train drivers and conductors for the Dutch railway operator NS Reizigers. The schedules were generated according to new rules originating from the project "Destination: Customer" ("Bestemming: Klant" in Dutch). This project is carried out by NS Reizigers in order to increase the quality and the punctuality of its train services. With respect to the scheduling of drivers and conductors, this project involves the generation of efficient and acceptable duties with a high robustness against the transfer of delays of trains. A key issue for the acceptability of the duties is the included amount of variation per duty. The applied set covering model is solved by dynamic column generation techniques, Lagrangean relaxation and powerful heuristics. The model and the solution techniques are part of the TURNI system, which is currently used by NS Reizigers for carrying out several analyses concerning the required capacities of the depots. The latter are strongly influenced by the new rules
Using phage Lytic Enzymes to Control Pathogenic Bacteria
Our laboratory has developed phage lytic enzymes to prevent infection by specifically destroying disease bacteria on mucous membranes and in blood. Enzymes specific for S. pneumoniae and S. pyogenes have been developed to be used nasally and orally to control these organisms in environments such as hospitals and nursing homes to prevent or markedly reduce serious infections by these pathogens. In addition, a B. anthracis-specific enzyme was developed to kill the vegetative forms of these bacteria in the blood of infected individuals. In animal studies, >80% of mice colonized mucosally or infected intravenously with pathogenic bacteria were decolonized or survived after a single enzyme treatment delivered to the same site of colonization or infection
Characterisation of the secondary-neutron production in particle therapy treatments with the MONDO tracking detector
Particle Therapy (PT) is a non-invasive technique that exploits charged light ions for the irradiation of tumours that cannot be effectively treated with surgery or conventional radiotherapy. While the largest dose fraction is released to the tumour volume by the primary beam, a non-negligible amount of additional dose is due to the beam fragmentation that occurs along the path towards the target volume. In particular, the produced neutrons are particularly dangerous as they can release their energy far away from the treated area, increasing the risk of developing a radiogenic secondary malignant neoplasm after undergoing a treatment. A precise measurement of the neutron flux, energy spectrum and angular distributions is eagerly needed in order to improve the treatment planning system software, so as to predict the normal tissue toxicity in the target region and the risk of late complications in the whole body. The MONDO (MOnitor for Neutron Dose in hadrOntherapy) project is dedicated to the characterisation of the secondary ultra-fast neutrons ([20-400] MeV energy range) produced in PT. The neutron tracking system exploits the reconstruction of the recoil protons produced in two consecutive (n, p) elastic scattering interactions to measure simultaneously the neutron incoming direction and energy. The tracker active media is a matrix of thin squared scintillating fibers arranged in orthogonally oriented layers that are read out by a sensor (SBAM) based on SPAD (Single-Photon Avalanche Diode) detectors developed in collaboration with the Fondazione Bruno Kessler (FBK)
Complete phenomenological gravitational waveforms from spinning coalescing binaries
The quest for gravitational waves from coalescing binaries is customarily
performed by the LIGO-Virgo collaboration via matched filtering, which requires
a detailed knowledge of the signal. Complete analytical coalescence waveforms
are currently available only for the non-precessing binary systems. In this
paper we introduce complete phenomenological waveforms for the dominant
quadrupolar mode of generically spinning systems. These waveforms are
constructed by bridging the gap between the analytically known inspiral phase,
described by spin Taylor (T4) approximants in the restricted waveform
approximation, and the ring-down phase through a phenomenological intermediate
phase, calibrated by comparison with specific, numerically generated waveforms,
describing equal mass systems with dimension-less spin magnitudes equal to 0.6.
The overlap integral between numerical and phenomenological waveforms ranges
between 0.95 and 0.99.Comment: Proceeding for the GWDAW-14 conference. Added reference in v
Relation Between Einstein And Quantum Field Equations
We show that there exists a choice of scalar field modes, such that the
evolution of the quantum field in the zero-mass and large-mass limits is
consistent with the Einstein equations for the background geometry. This choice
of modes is also consistent with zero production of these particles and thus
corresponds to a preferred vacuum state preserved by the evolution. In the
zero-mass limit, we find that the quantum field equation implies the Einstein
equation for the scale factor of a radiation-dominated universe; in the
large-mass case, it implies the corresponding Einstein equation for a
matter-dominated universe. Conversely, if the classical radiation-dominated or
matter-dominated Einstein equations hold, there is no production of scalar
particles in the zero and large mass limits, respectively. The suppression of
particle production in the large mass limit is over and above the expected
suppression at large mass. Our results hold for a certain class of conformally
ultrastatic background geometries and therefore generalize previous results by
one of us for spatially flat Robertson-Walker background geometries. In these
geometries, we find that the temporal part of the graviton equations reduces to
the temporal equation for a massless minimally coupled scalar field, and
therefore the results for massless particle production hold also for gravitons.
Within the class of modes we study, we also find that the requirement of zero
production of massless scalar particles is not consistent with a non-zero
cosmological constant. Possible implications are discussed.Comment: Latex, 24 pages. Minor changes in text from original versio
In-room test results at CNAO of an innovative PT treatments online monitor (Dose Profiler)
The use of C, He and O ions as projectiles in Particle Therapy (PT) treatments is getting more and more widespread as a consequence of their enhanced relative biological effectiveness and oxygen enhancement ratio, when compared to the protons one. The advantages related to the incoming radiation improved efficacy are requiring an accurate online monitor of the dose release spatial distribution. Such monitor is necessary to prevent unwanted damage to the tissues surrounding the tumour that can arise, for example, due to morphological changes occurred in the patient during the treatment with respect to the initial CT scan. PT treatments with ions can be monitored by detecting the secondary radiation produced by the primary beam interactions with the patient body along the path towards the target volume. Charged fragments produced in the nuclear process of projectile fragmentation can be emitted at large angles with respect to the incoming beam direction and can be detected with high efficiency in a nearly background-free environment. The Dose Profiler (DP) detector, developed within the INSIDE project, is a scintillating fibre tracker that allows an online reconstruction and backtracking of such secondary charged fragments. The construction and preliminary in-room tests performed on the DP, carried out using the 12C ions beam of the CNAO treatment centre using an anthropomorphic phantom as a target, will be reviewed in this contribution. The impact of the secondary fragments interactions with the patient body will be discussed in view of a clinical application. Furthermore, the results implications for a pre-clinical trial on CNAO patients, foreseen in 2019, will be discussed
Scintillating fiber devices for particle therapy applications
Particle Therapy (PT) is a radiation therapy technique in which solid tumors are treated with charged ions and exploits the achievable highly localized dose delivery, allowing to spare healthy tissues and organs at risk. The development of a range monitoring technique to be used on-line, during the treatment, capable to reach millimetric precision is considered one of the important steps towards an optimization of the PT efficacy and of the treatment quality. To this aim, charged secondary particles produced in the nuclear interactions between the beam particles and the patient tissues can be exploited. Besides charged secondaries, also neutrons are produced in nuclear interactions. The secondary neutron component might cause an undesired and not negligible dose deposition far away from the tumor region, enhancing the risk of secondary malignant neoplasms that can develop even years after the treatment. An accurate neutron characterization (flux, energy and emission profile) is hence needed for a better evaluation of long-term complications. In this contribution two tracker detectors, both based on scintillating fibers, are presented. The first one, named Dose Profiler (DP), is planned to be used as a beam range monitor in PT treatments with heavy ion beams, exploiting the charged secondary fragments production. The DP is currently under development within the INSIDE (Innovative Solutions for In-beam DosimEtry in hadrontherapy) project. The second one is dedicated to the measurement of the fast and ultrafast neutron component produced in PT treatments, in the framework of the MONDO (MOnitor for Neutron Dose in hadrOntherapy) project. Results of the first calibration tests performed at the Trento Protontherapy center and at CNAO (Italy) are reported, as well as simulation studies
An exact self-consistent gravitational shock wave in semiclassical gravity
We find a self-consistent pp-gravitational shock wave solution to the
semiclassical Einstein equations resulting from the approach to the
effective action. We model the renormalized matter stress-energy-momentum
tensor by massless scalar fields in the Minkowski vacuum plus a classical
particle. We show that quantum effects generate a milder singularity at the
position of the particle than the classical solution, but the singularity does
not disappear. At large distances from the particle, the quantum correction
decreases slowly, as ( being the distance to the particle in
the shock wave plane). We argue that this large distance correction is a
necessary consequence of quantum gravity.Comment: 13 pages, REVTEX, 4 PS figures. Revised version contains a derivation
of the solution compatible with its distributional character. The final
results, though, are the sam
Anchoring of proteins to lactic acid bacteria
The anchoring of proteins to the cell surface of lactic acid bacteria (LAB) using genetic techniques is an exciting and emerging research area that holds great promise for a wide variety of biotechnological applications. This paper reviews five different types of anchoring domains that have been explored for their efficiency in attaching hybrid proteins to the cell membrane or cell wall of LAB. The most exploited anchoring regions are those with the LPXTG box that bind the proteins in a covalent way to the cell wall. In recent years, two new modes of cell wall protein anchoring have been studied and these may provide new approaches in surface display. The important progress that is being made with cell surface display of chimaeric proteins in the areas of vaccine development and enzyme- or whole-cell immobilisation is highlighted.
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