tert-Butyl 2-hy­droxy-3-(4-methyl­benzene­sulfonamido)­butano­ate

In the crystal of the title compound, C15H23NO5S, mol­ecules are linked through N—H⋯O and O—H⋯O hydrogen-bond inter­actions, resulting in centrosymmetric dimers in which the N—H⋯O inter­actions generate R 2 2(12) rings and the O—H⋯O inter­actions generate R 2 2(14) rings. Weak inter­molecular C—H⋯O inter­actions are also observed

(2R,3S)-Methyl 2-hy­droxy-3-(4-methyl­benzene­sulfonamido)-3-phenyl­propano­ate

In the title mol­ecule, C17H19NO5S, the p-tolyl ring is oriented approximately parallel to the phenyl ring [dihedral angle = 17.2 (1)°], resulting in an intra­molecular π–π inter­ation [centroid–centroid distance = 3.184 (10) Å]. In the crystal, mol­ecules are linked through O—H⋯O and C—H⋯O hydrogen bonds, forming hydrogen-bonded sheets lying diagonally across the ac face

The Heterogeneous Aminohydroxylation Reaction Using Hydrotalcite-Like Catalysts Containing Osmium

The aminohydroxylation reaction of olefins is a key organic transformation reaction, typically carried out homogeneously with toxic and expensive osmium (Os) catalysts. Therefore, heterogenisation of this reaction can unlock its industrial potential by allowing reusability of the catalyst. Os⁻Zn⁻Al hydrotalcite-like compounds (HTlcs), as potential heterogeneous aminohydroxylation catalysts, were synthesised by the co-precipitation method and characterised by several techniques. Reaction parameters (i.e., solvent system, reaction temperature, and catalyst structure) were optimized with cyclohexene, styrene, and hexene as substrates. The different classes of olefins (aliphatic, aromatic, and functionalised) that were tested gave >99% conversion and high selectivity (>97%) to the corresponding β-amino alcohol. The catalyst HTlc structure had a significant effect on the reaction time and yield of the β-amino alcohols. Under the same testing conditions, a heat treated catalyst (non-HTlc) showed a shorter reaction time, but drop in the yield of β-amino alcohols and rise in diol formation was observed. Leaching tests showed that 2.9% and 3.4% of Os (inactive) leached from the catalyst to the reaction solution when MeCN/water (1:1 v/v) and t-BuOH/water (1:1 v/v), respectively, were used as the solvent system. Recycling studies showed that the catalyst can be reused at least thrice, with no significant difference in the yield of the β-amino-alcohol

cis-N-(2-Hydroxycyclohexyl)-p-toluenesulfonamide

There are two symmetry-independent molecules in the asymmetric unit of the title compound, C13H19NO3S. The cyclohexane rings in the two molecules adopt chair configurations. The hydroxy and amino groups on the cyclohexane ring assume axial and equatorial orientations, respectively, with respect to the plane of the ring. The crystal structure is stabilized by two intermolecular N—H...O and O—H...O hydrogen bonds from the two symmetry-independent molecules

Prevalence of gastrointestinal parasites in young camels in Bahrain

The prevalence of gastrointestinal parasites in young camels in Bahrain is reported for the first time. Six genera of parasites were found. The nematodes observed were Haemonchus contortus (36.47%), Nematodirus spathiger (30.59%) and Trichuris sp. (10.6%); the only cestode recorded was Moniezia expansa (2.4%). The incidence of Eimeria dromedarii was 20%. Single, double, triple and quadruple parasitic infestation occurred in 41.2, 33.5, 19.4 and 5.9% of the infected animals, respectively. Balantidium coli, a protozoan parasite, was occasionally seen in young camels suffering from diarrhea at the time of sampling

Catalysis as a driver for sustainable technologies in Africa – A perspective by the Catalysis Institute at the University of Cape Town

One of the biggest global challenges we are facing today is the provision of affordable, green, and sustainable energy to a growing population. Enshrined in multiple United Nation Sustainable Development Goals – Goal 7: Affordable and Clean Energy; Goal 11: Sustainable Cities and Communities; Goal 12: Responsible Consumption and Production and Goal 13: Climate Action – as well as at the core of the Paris Agreement, it is our task as scientists and engineers to develop innovative technologies that satisfy society's needs while pivoting away from the use of fossil resources. This is a mammoth task with an ambitious timeline. The global development of the industrial sector as we know it is solely based on the exploitation of energy-rich fossil fuels that remain cost-competitive today. However, a gradual change from a market driven to a policy-driven transition allows alternative technologies to make inroads and find applications. One of the most prominently discussed approaches is the Power-to-X (PtX) process envelope. It describes a series of catalytic conversions using only renewable energy, water and captured CO2 to produce green hydrogen, liquid hydrocarbon fuels and chemicals. Especially for sectors that are difficult or impossible to decarbonise, such processes that effectively defossilising the production of energy and goods, represent an important solution.The Catalysis Institute at the University of Cape Town (herein/after referred to as the Catalysis Institute) builds on decades of experience in the individual catalytic processes combined in the PtX concept. In collaboration with our global partners, we are therefore able to develop technologies for the full value chain, considering interdependencies and develop solutions for the African and indeed global society