2,207 research outputs found

    Incorporating spatial correlations into multispecies mean-field models

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    In biology, we frequently observe different species existing within the same environment. For example, there are many cell types in a tumour, or different animal species may occupy a given habitat. In modeling interactions between such species, we often make use of the mean-field approximation, whereby spatial correlations between the locations of individuals are neglected. Whilst this approximation holds in certain situations, this is not always the case, and care must be taken to ensure the mean-field approximation is only used in appropriate settings. In circumstances where the mean-field approximation is unsuitable, we need to include information on the spatial distributions of individuals, which is not a simple task. In this paper, we provide a method that overcomes many of the failures of the mean-field approximation for an on-lattice volume-excluding birth-death-movement process with multiple species. We explicitly take into account spatial information on the distribution of individuals by including partial differential equation descriptions of lattice site occupancy correlations. We demonstrate how to derive these equations for the multispecies case and show results specific to a two-species problem. We compare averaged discrete results to both the mean-field approximation and our improved method, which incorporates spatial correlations. We note that the mean-field approximation fails dramatically in some cases, predicting very different behavior from that seen upon averaging multiple realizations of the discrete system. In contrast, our improved method provides excellent agreement with the averaged discrete behavior in all cases, thus providing a more reliable modeling framework. Furthermore, our method is tractable as the resulting partial differential equations can be solved efficiently using standard numerical techniques

    Properties of implanted and CVD incorporated nitrogen-vacancy centers: preferential charge state and preferential orientation

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    The combination of the long electron state spin coherence time and the optical coupling of the ground electronic states to an excited state manifold makes the nitrogen-vacancy (NV) center in diamond an attractive candidate for quantum information processing. To date the best spin and optical properties have been found in centers deep within the diamond crystal. For useful devices it will be necessary to engineer NVs with similar properties close to the diamond surface. We report on properties including charge state control and preferential orientation for near surface NVs formed either in CVD growth or through implantation and annealing

    Production of oriented nitrogen-vacancy color centers in synthetic diamond

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    The negatively charged nitrogen-vacancy (NV-) center in diamond is an attractive candidate for applications that range from magnetometry to quantum information processing. Here we show that only a fraction of the nitrogen (typically < 0.5 %) incorporated during homoepitaxial diamond growth by Chemical Vapor Deposition (CVD) is in the form of undecorated NV- centers. Furthermore, studies on CVD diamond grown on (110) oriented substrates show a near 100% preferential orientation of NV- centers along only the [111] and [-1-11] directions, rather than the four possible orientations. The results indicate that NV centers grow in as units, as the diamond is deposited, rather than by migration and association of their components. The NV unit of the NVH- is similarly preferentially oriented, but it is not possible to determine whether this defect was formed by H capture at a preferentially aligned NV center or as a complete unit. Reducing the number of NV orientations from 4 orientations to 2 orientations should lead to increased optically-detected magnetic resonance contrast and thus improved magnetic sensitivity in ensemble-based magnetometry.Comment: 13 Pages (inlcuding suplementary information), 4 figure

    Using an intervention mapping approach to develop a discharge protocol for intensive care patients

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    Background: Admission into an intensive care unit (ICU) may result in long-term physical, cognitive, and emotional consequences for patients and their relatives. The care of the critically ill patient does not end upon ICU discharge; therefore, integrated and ongoing care during and after transition to the follow-up ward is pivotal. This study described the development of an intervention that responds to this need. Methods: Intervention Mapping (IM), a six-step theory- and evidence-based approach, was used to guide intervention development. The first step, a problem analysis, comprised a literature review, six semi-structured telephone interviews with former ICU-patients and their relatives, and seven qualitative roundtable meetings for all eligible nurses (i.e., 135 specialized and 105 general ward nurses). Performance and change objectives were formulated in step two. In step three, theory-

    Steady State Visual Stimulation of the Brain: Optical Study of Task Related Effects

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    Near-infrared (NIR) and electroencephalography (EEG) systems were applied simultaneously to check a possibility of an optical brain-computer interface (BCI) based on visual protocol. A two-wavelength, two-channel NIR system using lock-in amplifiers to filter received signal was designed for monitoring of light absorption. An improved single photon-counting system based on NIR laser diodes and multichannel scaling was configured for fast one-wavelength capturing of the scatter changes in the area of the human brain corresponding to the task. Designed protocols consisted of the pattern reversed repeatedly at various frequencies. The stimulus repetition improves processing according to some behavioural measure as e.g. greater accuracy in identifying the stimulus or faster response times to make a decision about it, and often occurs under the same experimental conditions. Under certain conditions rather increased activity in the brain could be observed which results in a longer habituation time. Results of tests are presented in current article

    A 12-Channel, real-time near-infrared spectroscopy instrument for brain-computer interface applications

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    A continuous wave near-infrared spectroscopy (NIRS) instrument for brain-computer interface (BCI) applications is presented. In the literature, experiments have been carried out on subjects with such motor degenerative diseases as amyotrophic lateral sclerosis, which have demonstrated the suitability of NIRS to access intentional functional activity, which could be used in a BCI as a communication aid. Specifically, a real-time, multiple channel NIRS tool is needed to realise access to even a few different mental states, for reasonable baud rates. The 12-channel instrument described here has a spatial resolution of 30mm, employing a flexible software demodulation scheme. Temporal resolution of ~100ms is maintained since typical topographic imaging is not needed, since we are only interested in exploiting the vascular response for BCI control. A simple experiment demonstrates the ability of the system to report on haemodynamics during single trial mental arithmetic tasks. Multiple trial averaging is not required

    The maximally entangled symmetric state in terms of the geometric measure

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    The geometric measure of entanglement is investigated for permutation symmetric pure states of multipartite qubit systems, in particular the question of maximum entanglement. This is done with the help of the Majorana representation, which maps an n qubit symmetric state to n points on the unit sphere. It is shown how symmetries of the point distribution can be exploited to simplify the calculation of entanglement and also help find the maximally entangled symmetric state. Using a combination of analytical and numerical results, the most entangled symmetric states for up to 12 qubits are explored and discussed. The optimization problem on the sphere presented here is then compared with two classical optimization problems on the S^2 sphere, namely Toth's problem and Thomson's problem, and it is observed that, in general, they are different problems.Comment: 18 pages, 15 figures, small corrections and additions to contents and reference

    Work-Unit Absenteeism: Effects of Satisfaction, Commitment, Labor Market Conditions, and Time

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    Prior research is limited in explaining absenteeism at the unit level and over time. We developed and tested a model of unit-level absenteeism using five waves of data collected over six years from 115 work units in a large state agency. Unit-level job satisfaction, organizational commitment, and local unemployment were modeled as time-varying predictors of absenteeism. Shared satisfaction and commitment interacted in predicting absenteeism but were not related to the rate of change in absenteeism over time. Unit-level satisfaction and commitment were more strongly related to absenteeism when units were located in areas with plentiful job alternatives
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