561 research outputs found
Construction of one-loop SYM effective action on the mixed branch in the harmonic superspace approach
We develop a systematic approach to construct the one-loop SYM
effective action depending on both vector multiplet and
hypermultiplet background fields. Beginning with the formulation of SYM theory in terms of harmonic superfields, we construct
the one-loop effective action using the covariant harmonic
supergraphs and calculate it in harmonic superfield form for
constant Abelian strength and corresponding constant hypermultiplet
fields. The hypermultiplet-dependent effective action is derived and given by
integral over the analytic subspace of harmonic superspace. We show that each
term in the Schwinger-De Witt expansion of the low-energy effective action is
written as integral over full superspace.Comment: 35 pages, JHEP styl
Higher order contributions to the effective action of N=2 super Yang-Mills
We apply heat kernel techniques in N=1 superspace to compute the one-loop
effective action to order for chiral superfields coupled to a non-Abelian
super Yang-Mills background. The results, when combined with those of
hep-th/0210146, yield the one-loop effective action to order for any N=2
super Yang-Mills theory coupled to matter hypermultiplets.Comment: 23 pages, references adde
The Effect of Cone Opsin Mutations on Retinal Structure and the Integrity of the Photoreceptor Mosaic
Purpose.
To evaluate retinal structure and photoreceptor mosaic integrity in subjects with OPN1LW and OPN1MW mutations.
Methods.
Eleven subjects were recruited, eight of whom have been previously described. Cone and rod density was measured using images of the photoreceptor mosaic obtained from an adaptive optics scanning light ophthalmoscope (AOSLO). Total retinal thickness, inner retinal thickness, and outer nuclear layer plus Henle fiber layer (ONL+HFL) thickness were measured using cross-sectional spectral-domain optical coherence tomography (SD-OCT) images. Molecular genetic analyses were performed to characterize the OPN1LW/OPN1MW gene array.
Results.
While disruptions in retinal lamination and cone mosaic structure were observed in all subjects, genotype-specific differences were also observed. For example, subjects with “L/M interchange” mutations resulting from intermixing of ancestral OPN1LW and OPN1MW genes had significant residual cone structure in the parafovea (∼25% of normal), despite widespread retinal disruption that included a large foveal lesion and thinning of the parafoveal inner retina. These subjects also reported a later-onset, progressive loss of visual function. In contrast, subjects with the C203R missense mutation presented with congenital blue cone monochromacy, with retinal lamination defects being restricted to the ONL+HFL and the degree of residual cone structure (8% of normal) being consistent with that expected for the S-cone submosaic.
Conclusions.
The photoreceptor phenotype associated with OPN1LW and OPN1MW mutations is highly variable. These findings have implications for the potential restoration of visual function in subjects with opsin mutations. Our study highlights the importance of high-resolution phenotyping to characterize cellular structure in inherited retinal disease; such information will be critical for selecting patients most likely to respond to therapeutic intervention and for establishing a baseline for evaluating treatment efficacy
Electrical transport through single-molecule junctions: from molecular orbitals to conduction channels
We present an atomistic theory of electronic transport through single organic
molecules that reproduces the important features of the current-voltage
characteristics observed in recent experiments. We trace these features to
their origin in the electronic structure of the molecules and their local
atomic environment. We demonstrate how conduction channels arise from the
molecular orbitals and elucidate which specific properties of the individual
orbitals determine their contribution to the current.Comment: Revtex4, 4 pages, 4 figures. Version with color figures in
http://www-tfp.physik.uni-karlsruhe.de/~cuevas/Publications.htm
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