Asymptotic Behavior of the Correlator for Polyakov Loops

The asymptotic behavior of the correlator for Polyakov loop operators separated by a large distance $R$ is determined for high temperature QCD. It is dominated by nonperturbative effects related to the exchange of magnetostatic gluons. To analyze the asymptotic behavior, the problem is formulated in terms of the effective field theory of QCD in 3 space dimensions. The Polyakov loop operator is expanded in terms of local gauge-invariant operators constructed out of the magnetostatic gauge field, with coefficients that can be calculated using resummed perturbation theory. The asymptotic behavior of the correlator is $\exp(-MR)/R$, where $M$ is the mass of the lowest-lying glueball in $(2+1)$-dimensional QCD. This result implies that existing lattice calculations of the Polyakov loop correlator at the highest temperatures available do not probe the true asymptotic region in $R$.Comment: 10 pages, NUHEP-TH-94-2

Functional interactions between polypyrimidine tract binding protein and PRI peptide ligand containing proteins.

Polypyrimidine tract binding protein (PTBP1) is a heterogeneous nuclear ribonucleoprotein (hnRNP) that plays roles in most stages of the life-cycle of pre-mRNA and mRNAs in the nucleus and cytoplasm. PTBP1 has four RNA binding domains of the RNA recognition motif (RRM) family, each of which can bind to pyrimidine motifs. In addition, RRM2 can interact via its dorsal surface with proteins containing short peptide ligands known as PTB RRM2 interacting (PRI) motifs, originally found in the protein Raver1. Here we review our recent progress in understanding the interactions of PTB with RNA and with various proteins containing PRI ligands.This work was supported by the Biotechnology and Biological Sciences Research Council [grant number BB/H004203/1 (to C.W.J.S.)]; the Wellcome Trust [grant number 092900 (to C.W.J.S.)]; the Boehringer Ingelheim Fond (to J.A.); the Medical Research Council [grant number MR/M026302/1 (to D.B.A. and D.E.V.P.)]; the Fundação de Amparo à Pesquisa do Estado de Minas Gerais [grant number MR/M026302/1 (to D.B.A. and D.E.V.P.)]; and the National Health and Medical Research Council CJ Martin Fellowship [grant number APP1072476 (to D.B.A.)]

On the equivalence between 2D Yukawa and Gross-Neveu models

We study numerically on the lattice the 2D Yukawa model with the U(1) chiral symmetry and $N_F$ = 16 at infinite scalar field self-coupling. The scaling behaviour of the fermion mass, as the Yukawa coupling approaches zero, is analysed using the mean field method. It is found to agree with that of the Gross-Neveu model with the same symmetry and $N_F$. The results suggest that the 2D Yukawa models belong to the universality class of the Gross-Neveu models not only at weak scalar field self-coupling but also for a broad range of the bare parameters which is not accessible to the $1/N_F$ expansion. New universality classes might arise at the crossover to the spin model universality class, however.Comment: 18 pages, Juelich HLRZ 111/9

Thermodynamics of lattice QCD with two light quark flavours on a 16^3 x 8 lattice II

We have extended our earlier simulations of the high temperature behaviour of lattice QCD with two light flavours of staggered quarks on a $16^3 \times 8$ lattice to lower quark mass (m_q=0.00625). The transition from hadronic matter to a quark-gluon plasma is observed at $6/g^2=5.49(2)$ corresponding to a temperature of $T_c \approx 140$MeV. We present measurements of observables which probe the nature of the quark-gluon plasma and serve to distinguish it from hadronic matter. Although the transition is quite abrupt, we have seen no indications that it is first order.Comment: 23 pages, RevteX, 6 encapsulated postscript figure

Quarkonium Suppression

I discuss quarkonium suppression in equilibriated strongly interacting matter. After a brief review of basic features of quarkonium production I discuss the application of recent lattice data on the heavy quark potential to the problem of quarkonium dissociation as well as the problem of direct lattice determination of quarkonium properties in finite temperature lattice QCD.Comment: Invited plenary talk presented on 4th International Conference on Physics and Astrophysics of Quark Gluon Plasma (ICPAQGP-2001), November 26-30, 2001, Jaipur; 12 pp, LaTeX, uses pramana.st

Heavy Quark Potentials in Quenched QCD at High Temperature

Heavy quark potentials are investigated at high temperatures. The temperature range covered by the analysis extends from $T$ values just below the deconfinement temperature up to about $4 T_c$ in the deconfined phase. We simulated the pure gauge sector of QCD on lattices with temporal extents of 4, 6 and 8 with spatial volumes of $32^3$. On the smallest lattice a tree level improved action was employed while in the other two cases the standard Wilson action was used. Below $T_c$ we find a temperature dependent logarithmic term contributing to the confinement potential and observe a string tension which decreases with rising temperature but retains a finite value at the deconfinement transition. Above $T_c$ the potential is Debye-screened, however simple perturbative predictions do not apply.Comment: 20 pages, 9 figure

Identification of potential therapeutic targets in prostate cancer through a cross-species approach.

Genetically engineered mouse models of cancer can be used to filter genome-wide expression datasets generated from human tumours and to identify gene expression alterations that are functionally important to cancer development and progression. In this study, we have generated RNAseq data from tumours arising in two established mouse models of prostate cancer, PB-Cre/PtenloxP/loxP and p53loxP/loxPRbloxP/loxP, and integrated this with published human prostate cancer expression data to pinpoint cancer-associated gene expression changes that are conserved between the two species. To identify potential therapeutic targets, we then filtered this information for genes that are either known or predicted to be druggable. Using this approach, we revealed a functional role for the kinase MELK as a driver and potential therapeutic target in prostate cancer. We found that MELK expression was required for cell survival, affected the expression of genes associated with prostate cancer progression and was associated with biochemical recurrence

Dynamics of a stretched nonlinear polymer chain

We study the relaxation dynamics of a coarse-grained polymer chain at different degrees of stretching by both analytical means and numerical simulations. The macromolecule is modelled as a string of beads, connected by anharmonic springs, subject to a tensile force applied at the end monomer of the chain while the other end is fixed at the origin of coordinates. The impact of bond non-linearity on the relaxation dynamics of the polymer at different degrees of stretching is treated analytically within the Gaussian self-consistent approach (GSC) and then compared to simulation results derived from two different methods: Monte-Carlo (MC) and Molecular Dynamics (MD). At low and medium degrees of chain elongation we find good agreement between GSC predictions and the Monte-Carlo simulations. However, for strongly stretched chains the MD method, which takes into account inertial effects, reveals two important aspects of the nonlinear interaction between monomers: (i) a coupling and energy transfer between the damped, oscillatory normal modes of the chain, and (ii) the appearance of non-vanishing contributions of a continuum of frequencies around the characteristic modes in the power spectrum of the normal mode correlation functions.Comment: 17 pages, 9 figure

Towards a Phenomenology of Grief : insights from Merleau-Ponty

This paper shows how phenomenological research can enhance our understanding of what it is to experience grief. I focus specifically on themes in the work of Maurice Merleau-Ponty, in order to develop an account that emphasizes two importantly different ways of experiencing indeterminacy. This casts light on features of grief that are disorienting and difficult to describe, while also making explicit an aspect of experience upon which the possibility of phenomenological inquiry itself depends

Addressing our planetary crisis: Consensus statement from the presenters and International Advisory Committee of the Regional Action on Climate Change (RACC) Symposium held in conjunction with the Kyoto-based Science and Technology in Society (STS) Forum, 1 October 2021.

12 month embargo; published: 01 November 2021This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]