Peculiarities of Sanitary and Quarantine Control under the Emergency Situation of Social Nature on the Adjacent Territory

Objective of the work is to perform the sanitary and quarantine control (SQC) in the under emergency situation of on the neighboring with the Russian Federation territory. Materials and methods. Utilized were information materials and report data of the Rospotrebnadzor Administration in the Rostov Region on the activities of automobile border-crossing points in high alert regime (2013–2016). Considered were some peculiarities of the sanitary and quarantine control (SQC) in the Rostov Region under emergency situations of social nature in the neighboring with the Russian Federation territories. Results and conclusions. Performance efficiency of the sanitary-quarantine facilities (SQF) in terms of inspection of vehicles and population testify to the consistently high traffic and flow of migration through multilateral automobile points of entry (APE) (2014–2016), followed by their redistribution between the APE in the context of the unfolding situation. SQC at state border checkpoints was carried out in the high alert regime to identify sick persons suspected of infectious diseases of various etiologies – the multi-etiological risk factors. Demonstrated is the expediency of “symptomatic” approach for identification of persons with suspected communicable diseases using the maximum of capacities of other government control agencies. The main peculiarities of the high alert regime under social conflict in the neighboring areas are the strengthening of interdepartmental cooperation with the Ministry of Emergency Situations (MES) and the Federal Medical-Biological Agency of Russia

Improvement of the Procedure for Sanitary and Quarantine Control of Ships in the Seaports

Objective of the work is to analyze the procedure of ship sanitary and quarantine control in the Rostov Region seaports in order to identify the risks for sanitary and epidemiological welfare of the population and to improve communication process between the authorized ports. Materials and methods. Ship sanitary and quarantine control data on 8314 ships that arrived at Rostov-on-Don, Azov and Taganrog sea border checkpoints were used, considering possible risks for the sanitary and epidemiological welfare of the population. Results and conclusions. The key risks for decision-making whether to perform ship sanitary and quarantine control at the sea border checkpoints are identified. At the stage of the implementation of IHR (2005) it is necessary to consider the ship sanitary and quarantine control at the sea border checkpoints as an unscheduled inspection; availability of preliminary information on the absence of valid sanitary certificates on ships arriving from abroad to be the ground for carrying out ship sanitary and quarantine control at the sea border checkpoints. In order to improve the communication process between authorized ports it is necessary to insert the results of the inspections into ship’s sanitary certificates with issuance of the revealed risks forms

Ebola Virus Disease and Epidemic Development in the West-African Countries in 2014 (Review)

The review presents the data on the development of epidemic caused by Ebola virus in the West-African countries - Liberia, Sierra Leone, Nigeria, Senegal, and Mali. Analyzed is also an epidemic in the Democratic Republic of the Congo, unrelated to the mentioned above outbreaks. Traced have been the chains of transmission and import of the disease (under control and out-of-control) into European and American states. Assessed are the premises for complications faced in the course of epidemic response, and the factors contributing to the wide spread of the infection

Analysis of the Results of Cholera Vibrios Monitoring in Environmental Objects in the Administrative Territories of the Russian Federation Using GIS “CHOLERA 1989–2014”

Objective of the work was to compare the results of monitoring of Vibrio cholerae strains isolated in the territories of federal districts, their constituent entities and from certain water bodies between 2006–2016. Based on the methodology, using updated geoinformation system “Cholera 1989–2014”, a comparative study of the dynamics of isolation and biological properties of 586 Vibrio cholerae O1, O139 strains and R-variants, collected from the surface water bodies in the administrative territories of Russia, was carried out. Eventually it is established that Vibrio cholerae strains of various serogroups are found in the territory of all federal districts, but not in all the entities included in them. It is shown that the greatest number of isolated strains was registered in the Southern Federal District. The overwhelming number of Vibrio cholerae strains, isolated in the country, were non-toxigenic. It was noted that against the background of epidemiological welfare, the detection of single epidemiologically significant strains continued (Rostov Region).ctxA–tcpA+ strains were found in the Southern, Far Eastern and North-Western Federal Districts. It is established that until 2013 in five constituent entities strains of Vibrio cholerae O1 and O139 in water bodies were not detected. Non-toxigenic strains of Vibrio cholerae O1 El Tor Ogawa serovar prevailed in the territories of the Southern and Ural, and Inaba serovar – in the remaining Federal Districts.The most frequently isolated were non-toxigenic Vibrio cholerae O1 strains with phagotype 15, while isolates with phagotypes 4, 5, 10, 14 and 17 were traced only in the Southern Federal District. The data obtained formed the basis of the approach that contributes to a comprehensive assessment of the epidemiological situation on cholera in the territory of Russia and highlighted the prospects for using GIS to improve the effectiveness of cholera vibrio monitoring in surface water bodies

Impact of Cultivating Environment on the Terms of Persistence and Certain Properties of Cholera Vibrios

Objective of the study is to investigate the impact of cultivating temperature and medium on the terms of persistence, ctx gene retention, and enzymatic activity of V. cholerae O1 with various toxigenicity.Materials and methods. Utilized were the strains of V. cholerae El Tor: P-5879, P-19613, and also the strain P-19787.Results and conclusions. In the process of studying cholera vibrios El Tor with different genetic characteristics it was determined that the longest terms of persistence (19 days) on mineral substrates at 5 ºC were observed for toxigenic strains, while for non-toxigenic ones it made less than 17 days. At the same time cholera vibrios can persist continuously and even reproduce on mineral substrates under the conditions of subnormal lowered temperatures (not less than 10 °C). Toxigenic strains of Vibrio cholerae, irrespectively of cultivating medium and temperature, retained ctx gene in their genome and maintained enzymatic activity throughout the experiment. Such long-term persistence of cholera vibrios at low temperatures on mineral substrates may be regarded as possibility of preservation of V. cholerae toxigenic strains in case of import by the infected persons or vibrio-carriers

Epidemiological Situation on Cholera throughout the World in 2013, Forecasting for 2014

V. cholerae O1 El Tor cultures, serovars Ogawa and Inaba, from surface waters of the reservoirs, which are different in epidemic manifestations of the disease

Characteristics of the Epidemiological Situation on Cholera the World Over

Within the last decade increase in cholera morbidity rate in the world has been revealed (with due consideration to linear trend). For 2013 maintenance of the tendency is forecasted. Epidemics, outbreaks and importations of the infection have occurred in 109 countries around Asia, Africa, America, Europe, Australia and Oceania. Nosoarea has been expanding owing to inclusion of new administrative territories and countries into the epidemic process, some cases being registered for the first time during the seventh pandemic. Apart from the endemic territories in India and Bangladesh, formation of endemic foci in twelve African countries has been exposed, as well as continued dissemination of epidemic cholera, consecutive in time and spatially stepwise. These facts testify of the follow-up of the seventh pandemic. Moreover, V. cholerae O1 El Tor strains with classical ctx-B allele have been spreading worldwide, which coupled with factors mentioned above predetermines unfavorable cholera forecast on the global level

EPIDEMIOLOGICAL SITUATION ON CHOLERA ACROSS THE GLOBE AND IN THE RUSSIAN FEDERATION IN 2007–2016. FORECAST FOR 2017

Analysis of epidemiological situation on cholera around the world has demonstrated downward trend in morbidity rates in 2016; annual average decline being 3.907 % (by reference to 2007). Comparative assessment of monthly incidence in 2015 and 2016 shows perennial registration of cholera cases in a number of African countries and in the Caribbean with up-rises in different seasons. Establishment of epidemic foci is on-going. Between 2007 and 2016, 1733 imported cases of cholera took place across the globe. Interstate import dominated in Asia. For forecast development, for the first time ever, risk assessment of epidemic process activation has been performed, taking into consideration emergency situations of varying origin, social and natural environments, using expert evaluation scores. Epidemic manifestations of cholera in the Russian Federation were characterized by import of the infection in 2008, 2010, 2012, and 2014; isolation of V. cholerae O1 biovar El Tor ctxA– tcpA–, ctxA+ and V. cholerae O139 ctxA– and tcpA– from surface water bodies, as well as individual V. cholerae O1 biovar El Tor сtхA+ tсра+. Worked out has been the algorithm for epidemiological investigation of causes and conditions of surface water body contamination with cholera vibrios. Cholera forecast worldwide and in Russia for the year 2017 remains unfavorable

EPIDEMIOLOGICAL SITUATION ON CHOLERA ACROSS THE GLOBE AND IN THE RUSSIAN FEDERATION IN 2007–2016. FORECAST FOR 2017

Analysis of epidemiological situation on cholera around the world has demonstrated downward trend in morbidity rates in 2016; annual average decline being 3.907 % (by reference to 2007). Comparative assessment of monthly incidence in 2015 and 2016 shows perennial registration of cholera cases in a number of African countries and in the Caribbean with up-rises in different seasons. Establishment of epidemic foci is on-going. Between 2007 and 2016, 1733 imported cases of cholera took place across the globe. Interstate import dominated in Asia. For forecast development, for the first time ever, risk assessment of epidemic process activation has been performed, taking into consideration emergency situations of varying origin, social and natural environments, using expert evaluation scores. Epidemic manifestations of cholera in the Russian Federation were characterized by import of the infection in 2008, 2010, 2012, and 2014; isolation of V. cholerae O1 biovar El Tor ctxA– tcpA–, ctxA+ and V. cholerae O139 ctxA– and tcpA– from surface water bodies, as well as individual V. cholerae O1 biovar El Tor сtхA+ tсра+. Worked out has been the algorithm for epidemiological investigation of causes and conditions of surface water body contamination with cholera vibrios. Cholera forecast worldwide and in Russia for the year 2017 remains unfavorable

Cholera: Epidemiological Situation around the World in 2005-2014, and Prognosis for 2015

Cholera epidemiological situation around the world (2005-2014) has been assessed. Distribution of infection in the territory of African, Asian, and American countries, as well as in the Caribbean Region has been shown. Interstate and inter-continental importations of cholera in Europe, Australia, and America, including USA and Canada have taken place during this period. Epidemic process is spatially disseminated (with involvement and affection of new countries and administrative territories) and temporally chronic (America, the Caribbean Region; Africa) due to occurring of natural or social emergency situations. Alongside epidemics and outbreaks of the disease, caused by genetically altered variants of V. cholerae O1 El Tor and strains with multiple drug resistance, outbreaks with isolation of clinical strains of V. cholerae O139 serogroup take place in the Southeast Asia (China) on an annual basis. The forecast for 2015, as regards cholera in the world, stays unfavorable, which in its turn allows for the possibility to import this infection in the territory of the Russian Federation