89 research outputs found
The extent of the psychological impairment of prosthodontic outpatients at a German University Hospital
Identification and characterisation of xylanolytic yeasts isolated from decaying wood and sugarcane bagasse in Brazil
Differential effects of hydrocortisone (HC) on mitogen induced proliferation and Ig synthesis of lymphocytes depend on the interaction of monocytes and activated T cells
Auditory cortex reflects goal-directed movement but is not necessary for behavioral adaptation in sound-cued reward tracking
Mounting evidence suggests that the role of sensory cortices in perceptual decision making goes beyond the mere representation of the discriminative stimuli, and additionally involves the representation of non-sensory variables such as reward expectation. However, the relevance of these representations for behavior is not clear. To address this issue, we trained rats to discriminate sounds in a single-interval forced choice task, and then confronted animals with unsignaled blockwise changes of reward probabilities. We found that unequal reward probabilities for the two choice options led to substantial shifts in response bias without concomitant reduction in stimulus discrimination. Although decisional biases were on average less extreme than required to maximize overall reinforcement, a model-based analysis revealed that rats managed to harvest >97 of rewards. Neurons in auditory cortex recorded during task performance weakly differentiated the discriminative stimuli but more strongly the subsequent goal-directed movement. While 10-20 of units exhibited significantly different firing rates between task epochs with different response biases, control experiments showed this to result from inflated false-positive rates resulting from unspecific temporal correlations of spiking activity, rather than changing reinforcement contingencies. Transient pharmacological inactivation of auditory cortex reduced sound discriminability without affecting other measures of performance, whereas inactivation of medial prefrontal cortex affected both discriminability and bias. Together, these results suggest that auditory cortex activity only weakly reflects decisional variables during flexible updating of stimulus-response-outcome contingencies and does not play a crucial role in sound-cued adaptive behavior, beyond the representation of the discriminative stimuli
Zum Einfluß von Heparinen und Adenosinphosphorsäuren auf Substrate und Aktivität der Mono- und Diaminoxydasen
Towards forensic-ready software systems
As software becomes more ubiquitous, and the risk of cyber-crimes
increases, ensuring that software systems are forensic-ready (i.e.,
capable of supporting potential digital investigations) is critical.
However, little or no attention has been given to how well-suited
existing software engineering methodologies and practices are for
the systematic development of such systems. In this paper, we consider
the meaning of forensic readiness of software, define forensic
readiness requirements, and highlight some of the open software
engineering challenges in the face of forensic readiness. We use
a real software system developed to investigate online sharing of
child abuse media to illustrate the presented concepts
Zur Orthotopie der histochemisch erfa�baren Aminopeptidasenaktivit�t der menschlichen Haut
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