2-aminoaethanesulfonic acid compounds possess protective property in reperfusion-induced heart jnjury

The study aim was to explore pharmacological effects of 2-aminoaethansulfonic acid compounds in reperfusion-induced heart injury. The study was performed on rats and dogs of both sexes, isolated rats’ hearts. Two compounds of 2-aminoethanesulfonic acid, magnesium-containing (LBK-527) and phenylacetamide-containing (LKhT-317) were investigate

The collection of oat genetic resources held by VIR as a source of information on the history of cultivation and taxonomy of the genus, and breeding trends (a review)

Oat is one of the leading cereals cultivated in the world and in Russia; it has an important fodder and nutritional value. To preserve the entire crop agrobiodiversity worldwide, there is a network of genebanks that hold more than 200,000 oat accessions. International and national genebanks are located in all the world’s countries, but one of the largest oat collections is located in Russia.The global collection of the genus Avena L. (Oats) at the N.I. Vavilov All-Russian Institute of Plant Genetic Resources (VIR) is one of the largest worldwide and consists of over 13,000 accessions. The collection preserves and maintains live accessions of all cultivated oat species: A. sativa L., A. byzantina K. Koch, A. strigosa Schreb. and A. abyssinica Hochst., landraces, breeding lines, spring and winter forms, covered and naked genotypes, and all geographic diversity of 22 wild Avena spp. from 50 countries. This review provides historical background of the collection of cultivated and wild oat species, and who were the main donors of these holdings. The taxonomic system of the genus is briefly presented, which is used as a tool for efficient work and guaranteed safe preservation of accessions. Most of the cultivars developed in Russia have in their pedigree accessions obtained from the global collection of VIR. The passport database contains detailed information about all accessions of the collection, which makes it possible to improve the work with the oat collection, including safe preservation of accessions and their effective evaluation and use as source material for breeding in the leading breeding centers of Russia.Thus, the global oat collection at VIR has factual and potential value for the sustainable development of environmentally friendly agriculture, efficient processing of agricultural products, and production of safe and high-quality food products, including functional foods

Evaluation of aluminum tolerance diversity in <i>Avena sativa</i> L. from the VIR collection

Background. Oat is an important food and feed cereal crop in Russia. The area under oats is 10 million ha worldwide, and 3 million ha in Russia. Acid soils with excessive content of exchangeable aluminum occupy almost every third hectare in the ex-USSR territory. Oats are relatively resistant to unfavorable soil factors. Among cereal crops, oat is second only to rye and triticale in terms of resistance to exchangeable Al forms. Despite the crop’s high environmental plasticity, an important condition for obtaining sustainable oat yields is the development of new cultivars with resistance to adverse environmental factors, including metal toxicity and high soil acidity.The objective of this work was to search for oat cultivars resistant to soil stressors (excess of Н+ and Al3+) for use in breeding for edaphic resistance.Materials and methods. The research material included 687 oat accessions from the VIR global plant genetic resources collection. The accessions underwent laboratory evaluation of their aluminum tolerance at the initial growth and development stages using the method of measuring radicle growth after the exposure to aluminum stress. Reproducibility of the used modification of the method was mathematically proved.Results and discussion. Significant variation in the resistance to the studied stressor was observed among the accessions. The regions acting as sources of valuable aluminum resistance genes were identified for the crop. The accessions selected for their high resistance to exchangeable aluminum can be used in breeding programs to develop high-yielding oat cultivars with edaphic resistance

Selectivity control of dicaffeoylquinic acids separation in reversed-phase hplc with β-cyclodextrine in a mobile phase

The paper investigates the change in the separation selectivity of the chlorogenic (mono- and dicaffeoylquinic) acids under conditions of reverse-phase HPLC with the addition of β-cyclodextrin into the mobile phas

Diversity of photoperiodic responses in oats

The article presents the results of an evaluation of the earliness and photoperiodic response (PPR) in the long-day oat accessions  of various geographic origin. The material for this study were 139 oat accessions  from the global collection of plant genetic resources  maintained by the Vavilov Institute (VIR), which included  landraces, breeding cultivars, and lines. In addition,  the donors  of low sensitivity to photoperiod developed at VIR were tested. A preliminary field study of the oat collection for early maturity and growing plants in the vegetation experiment was carried out according to the VIR Guidelines. The early accessions from VIR’s oat collection identified in the field showed a great diversity of their photoperiodic responses during the vegetation experiment in a photoperiod facility. By origin, most of the accessions described in the vegetation experiment as earliness  and weakly responsive to photoperiod were from Brazil (66 %); others from the USA, Portugal, Turkey, Colombia and Australia. Most of the Russian cultivars studied (77 %) were sensitive to a short  photoperiod. Among donors  with different  photoperiodic responses, Skorospely 1 and  Skorospely 2 were weakly responsive to photoperiod, while Srednespely 1 and  Srednespely 2 showed medium  responses. Many years of field studies  and vegetation experiments with the  oat genetic diversity from the VIR global collection  have resulted in identifying genotypes characterized by earliness and weak photoperiodic responses. These accessions  are of special value for breeders and currently being used to develop new early and productive oat cultivars

Diversity of avenanthramide content in wild and cultivated oats

Background. Oat grains accumulate substantial amounts of various phenolic compounds that possess biological activity and have a potential to considerably increase health benefits of oats as a food. Avenanthramides (AVA) is an important group of these compounds due to their antioxidant, anti-itching, anti-inflammatory, antiproliferative activities.Materials and methods. Using combined HPLC and LC-MS analyses, we provide the first comprehensive review of the total avenanthramide content and composition in cultivated and wild oats. The AVA content was measured in 32 wild and 120 cultivated oat accessions obtained from the global collection of the N.I. Vavilov Institute of Plant Genetic Resources (VIR), St. Petersburg, Russia.Results and conclusion. The wild hexaploid A. sterilis L. had the highest total AVA content, reaching 1825 mg kg–1. Among cultivated accessions, naked oat cv. ‘Numbat’ (Australia) had the highest AVA content, 586 mg kg–1. The AVA composition exhibited a wide diversity among the analyzed samples. Accessions were identified where AVAs A, B and C, which are generally considered as major AVA, had a low percentage, and instead other AVAs prevailed. The AVA content in eight oat cultivars revealed significant annual changes in both the total AVA content and the proportions of individual AVAs. Using HPLC analyses, 22 distinguishable peaks in AVA extracts of oat seeds were detected and quantified. Several of these peaks, which have not been previously documented, presumably represent different AVAs. Further analyses are needed to detail these findings and to determine the specific AVA structures in oat grains

May Measurement Month 2017 in Russia: hypertension treatment and control-Europe

Elevated blood pressure (BP) is a growing burden worldwide, leading to over 10 million deaths each year. May Measurement Month (MMM) is a global initiative by the International Society of Hypertension aimed at raising awareness of high BP and to act as a temporary solution to the lack of screening programs worldwide. The most recent publication compared data from three surveys performed in Russian population aged 25-64 showed that the prevalence of hypertension increased by approximately 20% from 2003 to 2013. This study presents screening data collected in 2017 though the MMM17 initiative in Russia. An opportunistic cross-sectional survey of volunteers aged ≥18 was carried out in May 2017 in 19 Russian cities. Blood pressure measurement, the definition of hypertension, and statistical analysis followed the standard MMM protocol. The recruitment of MMM17 participants in Russia occurred in shopping malls, colleges and universities, supermarkets, business centres, parks, and squares. Russian young cardiologists as an official section of Russian Society of Cardiology was actively involved. A total of 5660 individuals were screened. After multiple imputation, 2709 (47.9%) had hypertension. Of individuals not receiving antihypertensive medication, 753 (20.3%) were hypertensive. Of individuals receiving antihypertensive medication, 1094 (55.9%) had uncontrolled BP. Comparing with the worldwide results of MMM17 screening, Russian participants had a higher proportion of hypertension, comparable antihypertensive prescription rate, and worse hypertension control. Thus, the MMM17 project appears to be an important step in evaluating hypertension burden in Russia and emphasizes the further need to improve hypertension awareness, treatment, and control

Aluminum tolerance and micronutrient content in the grain of oat cultivars with different levels of breeding improvement from the VIR collection

Background. Soil toxicity of Al is associated with severe changes in plant root morphology that limit the uptake of water and mineral nutrients. Long-term exposure to Al results in deficiencies in some important nutrients, such as phosphorus, calcium, magnesium, potassium, and iron. Thus, the joint study of plant resistance to the effects of Al and the accumulation of micronutrients in the oat grain is relevant.Materials and methods. Thirty oat accessions of Russian and French origin from the VIR collection served as the research material. They were represented by cultivars with different levels of breeding improvement: landraces (early 1920s), cultivars developed by primitive breeding (1920–1930s), and modern improved cultivars.Results. Oat cultivars with different breeding improvement levels demonstrated significant differences in the content of micronutrients and aluminum tolerance. Among the studied accessions, landraces and modern improved cultivars showed a tendency towards medium or high Al tolerance, the group of primitive cultivars from Russia had the lowest Al tolerance, while primitive cultivars from France demonstrated the highest average resistance (0.5–1.9).Conclusion. The content of Fe and Zn was influenced by the geographic origin of genotypes. The concentrations of different micronutrients positively correlated with each other. Strong correlations were recorded between the contents of Zn and Fe (r = 0.81), and between Zn and Mg (r = 0.75). There was a positive correlation between the content of micronutrients and the resistance to crown rust (0.38 to 0.50). High content of the studied set of micronutrients was registered in such improved cultivars from France as the naked ‘Avoine Nue Renne’, ‘Chantilly’, ‘Negrita’ and ‘Noire de Michamps’, plus the Russian improved naked cultivar ‘Gavrosh’. Among them, ‘Chantilly’ was distinguished for its yield, and the naked ‘Gavrosh ‘for its high tolerance to aluminum

The Role of Internet Resources in the Formation of Ecological Culture

В данной статье дана оценка современной экологической ситуации. Показано влияние интернет-ресурсов на повышение экологической культуры. Рассмотрена роль экогайдов в формировании экологического сознания и экопривычек населения.This article assesses the current environmental situation, shows the influence of Internet resources on improving ecological culture and considers the role of eco-guides in the formation of ecological awareness and ecological habits of residents