54 research outputs found

    Looking to the future of zebrafish as a model to understand the genetic basis of eye disease

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    In this brief commentary, we provide some of our thoughts and opinions on the current and future use of zebrafish to model human eye disease, dissect pathological progression and advance in our understanding of the genetic bases of microphthalmia, andophthalmia and coloboma (MAC) in humans. We provide some background on eye formation in fish and conservation and divergence across vertebrates in this process, discuss different approaches for manipulating gene function and speculate on future research areas where we think research using fish may prove to be particularly effective

    A conception of the valuation of the vehicles' maintanance system in municipal public transport services

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    Rozporządzeniem (WE) nr 1370/2007 oraz ustawą o publicznym transporcie zbiorowym określone zostały nowe zasady organizacji i finansowania przewozów użyteczności publicznej. W artykule przedstawiono wpływ tych aktów prawnych na funkcjonowanie rynku lokalnych i regionalnych przewozów pasażerskich.Regulation (EC) No 1370/2007 of the European Parliament and of the Council of 23 October 2007 on public passenger transport services by rail and by road and repealing Council Regulations (EEC) Nos 1191/69 and 1107/70 and the Act of 16 December 2010 on public transport, are laid down new rules for the organization and financing of public transport. The paper presents the impact of these acts on the functioning of local and regional passenger transport
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