DIURESIS (FUNCTIONAL) ECHOGRAPHY AND ITS SIGNIFICANCE FOR THE DIAGNOSIS OF CONGENITAL URINARY TRACT ANOMALIES IN CHILDHOOD

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PECULIARITIES IN THE CLINICAL COURSE OF HODGKIN'S AND NON-HODGKIN'S LYMPHOMA IN CHILDREN

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THE INFLUENCE OF PYRACETAM ON THROMBOCYTOPOIESIS IN RATS

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CLINICAL PECULIARITIES OF ARTHRALGIA IN CHILDREN

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INVESTIGATION INTO THE RESERPINE EFFECT ON SOME HEMOSTASIS INDICATORS IN WHITE RATS

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AMINO ACID PROFILE OF CHILDREN WITH MALIGNANT HAEMOPATHIES AND LYMPHOMAS

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DIAGNOSTICS OF NEUROLEUKEMIA IN CHILDHOOD

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INFLUENCE OF BETA-ADRENOBLOCKADE WITH PROPRANOLOLUM UPON BLOOD-THROMB-FORMATION IN MICE

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INFLUENCE OF PIRACETAM ON ERYTHROPOIESIS IN RATS

The effects of piracetam (2 x 200 mg/kg b. w.) injected intraperitoneally for three days on erythropoiesis and some functional characteristics of erythrocytes were studied in Wistar rats. A significant increase of reticulocytes in relative (by 122,03 %, p < 0,01) and in absolute counts (by 109,29 %, p < 0,01), an increase of 59Fе incorporation in newly-formed erythrocytes (by 13,80 %) and a significant rise of erythroblasts as followed: total counts (by 59,39 %, p < 0,01), proerythroblasts (by 52,87 %, p < 0,05), and orthochromatic erythroblasts (by 54,25 %, p< 0,01) were observed in the piracetamtreated rats. It was accepted that piracetam stimulated erythroid proliferation and differentiation. Erythroid deformability enhanced by 14,69 % (p < 0,01) but spontaneous haemolysis of erythrocytes reduced by 16,95 % (p < 0,025). Thus it could be suggested that piracetam, along with its stimulatory effect on erythropoiesis, improves some of the most important functional characteristics of erythrocytes such as deformability and oxidative resistance