2 research outputs found

    ΠžΡ†Π΅Π½ΠΊΠ° эффСктивности оптичСской ΠΊΠΎΠ³Π΅Ρ€Π΅Π½Ρ‚Π½ΠΎΠΉ Ρ‚ΠΎΠΌΠΎΠ³Ρ€Π°Ρ„ΠΈΠΈ Π² диагностикС Ρ„ΠΎΠ½ΠΎΠ²Ρ‹Ρ… Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ шСйки ΠΌΠ°Ρ‚ΠΊΠΈ

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    The article presents the results of the use of optical coherence tomography (OCT) in the diagnosis of background diseases of the cervix. A compact portable optical tomograph OCT 1300-U was used. 102 women with background diseases of the cervix at the age of 19 to 43 years were examined. The following pathology of the cervix was revealed: ectopia in-50 patients (49 %), leukoplakia in - 36 (35.3 %), endometriosis in - 9 (8.8 %), flat condyloma of the cervix in - 7 (6.9 %). The OCT method is able to detect the layers and interstitial elements of the mucosa. The degree of structure loss in the tomograms corresponds to the increase in the severity of the process and the severity of colposcopic changes and is comparable with the histological data. The findings suggest that optical coherence tomography provides visualization the morphological structure of the cervical mucosa in normal and benign pathology at the level of layers and interstitial elements in form of structural optical images, which can be used for definition of optical characteristics of pathological processes in the cervix.Π’ ΡΡ‚Π°Ρ‚ΡŒΠ΅ ΠΏΡ€ΠΈΠ²Π΅Π΄Π΅Π½Ρ‹ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ примСнСния оптичСской ΠΊΠΎΠ³Π΅Ρ€Π΅Π½Ρ‚Π½ΠΎΠΉ Ρ‚ΠΎΠΌΠΎΠ³Ρ€Π° Ρ„ΠΈΠΈ (ОКВ) Π² диагностикС Ρ„ΠΎΠ½ΠΎΠ²Ρ‹Ρ… Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ шСйки ΠΌΠ°Ρ‚ΠΊΠΈ. использован ΠΊΠΎΠΌΠΏΠ°ΠΊΡ‚Π½Ρ‹ΠΉ пСрСносной оптичСский Ρ‚ΠΎΠΌΠΎΠ³Ρ€Π°Ρ„ ОКВ 1300-Π£ ОбслСдовано 102 ΠΆΠ΅Π½Ρ‰ΠΈΠ½ с Ρ„ΠΎΠ½ΠΎΠ²Ρ‹ΠΌΠΈ заболСваниями шСйки ΠΌΠ°Ρ‚ΠΊΠΈ Π² возрастС ΠΎΡ‚ 19 Π΄ΠΎ 43 Π»Π΅Ρ‚. ВыявлСна ΡΠ»Π΅Π΄ΡƒΡŽΡ‰Π°Ρ патология шСйки ΠΌΠ°Ρ‚ΠΊΠΈ: эктопия Ρƒ 50 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠΊ (49 %), лСйкоплакия Ρƒ 36 (35,3 %), эндомСтриоз Ρƒ 9 (8,8 %), плоская ΠΊΠΎΠ½Π΄ΠΈΠ»ΠΎΠΌΠ° шСйки ΠΌΠ°Ρ‚ΠΊΠΈ Ρƒ 7 (6,9 %). ΠœΠ΅Ρ‚ΠΎΠ΄ ОКВ способСн Π΄ΠΈΡ„Ρ„Π΅Ρ€Π΅Π½Ρ†ΠΈΡ€ΠΎΠ²Π°Ρ‚ΡŒ слои ΠΈ Π²Π½ΡƒΡ‚Ρ€ΠΈΡ‚ΠΊΠ°Π½Π΅Π²Ρ‹Π΅ элСмСнты слизистой. ΠŸΠΎΡ‚Π΅Ρ€Ρ структурности Π½Π° Ρ‚ΠΎΠΌΠΎΠ³Ρ€Π°ΠΌΠΌΠ°Ρ… происходит ΠΏΠ°Ρ€Π°Π»Π»Π΅Π»ΡŒΠ½ΠΎ ΡƒΠ²Π΅Π»ΠΈΡ‡Π΅Π½ΠΈΡŽ тяТСсти процСсса ΠΈ выраТСнности ΠΊΠΎΠ»ΡŒΠΏΠΎΡΠΊΠΎΠΏΠΈΡ‡Π΅ΡΠΊΠΈΡ… ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ ΠΈ сопоставима с Π΄Π°Π½Π½Ρ‹ΠΌΠΈ гистологичСского исслСдования. ΠŸΠΎΠ»ΡƒΡ‡Π΅Π½Π½Ρ‹Π΅ Π΄Π°Π½Π½Ρ‹Π΅ ΡΠ²ΠΈΠ΄Π΅Ρ‚Π΅Π»ΡŒΡΡ‚Π²ΡƒΡŽΡ‚, Ρ‡Ρ‚ΠΎ оптичСская когСрСнтная томография позволяСт Π²ΠΈΠ·ΡƒΠ°Π»ΠΈΠ·ΠΈΡ€ΠΎΠ²Π°Ρ‚ΡŒ ΠΌΠΎΡ€Ρ„ΠΎΠ»ΠΎΠ³ΠΈΡ‡Π΅ΡΠΊΡƒΡŽ структуру слизистой ΠΎΠ±ΠΎΠ»ΠΎΡ‡ΠΊΠΈ шСйки ΠΌΠ°Ρ‚ΠΊΠΈ Π² Π½ΠΎΡ€ΠΌΠ΅ ΠΈ ΠΏΡ€ΠΈ доброкачСствСнной ΠΏΠ°Ρ‚ΠΎΠ»ΠΎΠ³ΠΈΠΈ Π½Π° ΡƒΡ€ΠΎΠ²Π½Π΅ слоСв ΠΈ Π²Π½ΡƒΡ‚Ρ€ΠΈΡ‚ΠΊΠ°Π½Π΅Π²Ρ‹Ρ… элСмСнтов Π² Π²ΠΈΠ΄Π΅ структурных оптичСских ΠΎΠ±Ρ€Π°Π·ΠΎΠ² ΠΈ Π½Π° ΠΈΡ… основании Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚Π°Ρ‚ΡŒ оптичСскиС характСристики патологичСских процСссов шСйки ΠΌΠ°Ρ‚ΠΊΠΈ

    Outlooks of photodynamic therapy for the treatment of cervical diseases in routine clinical practice

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    Cervical cancer is one of the most common malignancies. Despite the existence of well-developed classical approaches to prevention, diagnosis, and treatment, cervical cancer demonstrates one of the highest incidence and mortality rates among female cancers. Cervical diseases are widespread, can develop at any age, and often preceded cancer development. Photodynamic therapy (PDT) is a new and unique treatment for cancer and a number of non-malignant diseases, which is based on systemic or topical administration of photosensitizers, followed by laser exposure. We analyzed foreign and Russian articles published between 2004 and 2018 evaluating the efficacy of PDT in patients with precancerous diseases and early cervical cancer. PDT is a highly effective treatment method, which causes no complications and can eliminate human papilloma virus. We assessed potential outlooks of wide clinical use of PDT. Β© 2020, Dynasty Publishing House. All rights reserved
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