1,597 research outputs found
Influence of pions on the hadron-quark phase transition
In this work we present the features of the hadron-quark phase transition
diagrams in which the pions are included in the system. To construct such
diagrams we use two different models in the description of the hadronic and
quark sectors. At the quark level, we consider two distinct parametrizations of
the Polyakov-Nambu-Jona-Lasinio (PNJL) models. In the hadronic side, we use a
well known relativistic mean-field (RMF) nonlinear Walecka model. We show that
the effect of the pions on the hadron-quark phase diagrams is to move the
critical end point (CEP) of the transitions lines. Such an effect also depends
on the value of the critical temperature (T_0) in the pure gauge sector used to
parametrize the PNJL models. Here we treat the phase transitions using two
values for T_0, namely, T_0 = 270 MeV and T_0 = 190 MeV. The last value is used
to reproduce lattice QCD data for the transition temperature at zero chemical
potential.Comment: 3 pages. Proceedings of XXXV Reuni\~ao de Trabalhos sobre F\'isica
Nuclear no Brasil 201
Fatores de Risco para o Desenvolvimento de SĂndrome PĂłs-Quimioembolização apĂłs Quimioembolização Hepática para Tratamento de Hepatocarcinoma
Introduction: Hepatic transarterial chemoembolization is a widely used technique for the treatment of hepatocellular carcinoma. The most common complication of this procedure is postembolization syndrome. The main objective of this study was to assess risk factors for the development of postembolization syndrome.
Material and Methods: Single-centre retrospective analysis of 563 hepatic transarterial chemoembolization procedures from January 1st, 2014 – December 31st, 2015. Hepatic transarterial chemoembolization was performed with ½ - 2 vials of 100 - 300 μm microspheres loaded with doxorubicin. Patients who experienced postembolization syndrome were identified based on prolongation of hospitalization due to pain, fever, nausea and/or vomiting. A control group with the patients who did not have postembolization syndrome was randomly created (three controls for one case). Descriptive analysis and multivariate logistic regression were performed.
Results: The overall prevalence of postembolization syndrome was 6.2%. Hepatic transarterial chemoembolization with doxorubicin dosage above 75 mg (more than one vial), the size of the largest nodule and female gender had statistically significant relation with development of postembolization syndrome (p = 0.030, p = 0.046 and p = 0.037, respectively).
Discussion: Doxorrubicin dosage above 75 mg is associated with a higher risk of postembolization syndrome. This result can be helpful for decision-making in clinical practice, whenever it is possible to avoid a higher dose without compromising the efficacy of the treatment. The size of the largest nodule and female gender also constitute risk factors for postembolization syndrome. The other variables studied were not related to the development of postembolization syndrome.
Conclusion: The dose of doxorrubicin, the size of the largest nodule treated and female gender are potential risk factors for the development of postembolization syndrome after hepatic transarterial chemoembolization for hepatocellular carcinoma.info:eu-repo/semantics/publishedVersio
Conditional large Fock state preparation and field state reconstruction in Cavity QED
We propose a scheme for producing large Fock states in Cavity QED via the
implementation of a highly selective atom-field interaction. It is based on
Raman excitation of a three-level atom by a classical field and a quantized
field mode. Selectivity appears when one tunes to resonance a specific
transition inside a chosen atom-field subspace, while other transitions remain
dispersive, as a consequence of the field dependent electronic energy shifts.
We show that this scheme can be also employed for reconstructing, in a new and
efficient way, the Wigner function of the cavity field state.Comment: 4 Revtex pages with 3 postscript figures. Submitted for publicatio
Gold electrode modified by self-assembled monolayers of thiols to determine DNA sequences hybridization
The process of immobilization of biological molecules is one of the most important steps in
the construction of a biosensor. In the case of DNA, the way it exposes its bases can result in electrochemical
signals to acceptable levels. The use of self-assembled monolayer that allows a connection to
the gold thiol group and DNA binding to an aldehydic ligand resulted in the possibility of determining
DNA hybridization. Immobilized single strand of DNA (ssDNA) from calf thymus pre-formed from
alkanethiol film was formed by incubating a solution of 2-aminoethanothiol (Cys) followed by glutaraldehyde
(Glu). Cyclic voltammetry (CV) was used to characterize the self-assembled monolayer on the
gold electrode and, also, to study the immobilization of ssDNA probe and hybridization with the complementary
sequence (target ssDNA). The ssDNA probe presents a well-defined oxidation peak at
+0.158 V. When the hybridization occurs, this peak disappears which confirms the efficacy of the annealing
and the DNA double helix performing without the presence of electroactive indicators. The use of
SAM resulted in a stable immobilization of the ssDNA probe, enabling the hybridization detection without
labels. This study represents a promising approach for molecular biosensor with sensible and reproducible
results
Field quantization in inhomogeneous anisotropic dielectrics with spatio-temporal dispersion
A quantum damped-polariton model is constructed for an inhomogeneous
anisotropic linear dielectric with arbitrary dispersion in space and time. The
model Hamiltonian is completely diagonalized by determining the creation and
annihilation operators for the fundamental polariton modes as specific linear
combinations of the basic dynamical variables. Explicit expressions are derived
for the time-dependent operators describing the electromagnetic field, the
dielectric polarization and the noise term in the latter. It is shown how to
identify bath variables that generate the dissipative dynamics of the medium.Comment: 24 page
Comparing protocols for preparation of DNA-free total yeast RNA suitable for RT-PCR
BACKGROUND: Preparation of RNA free from DNA is a critical step before performing RT-PCR assay. Total RNA isolated from several sources, including those obtained from Saccharomyces cerevisiae, using routine methodologies are frequently contaminated with DNA, which can give rise to amplification products that mimic the amplicons expected from the RNA target. RESULTS: We investigated the efficiency of two DNase I based protocols for eliminating DNA contaminations from RNA samples obtained from yeast cells. Both procedures are very efficient in eliminating DNA contamination from RNA samples and entail three main steps, which involve treating of RNA samples with DNase I, inhibition of the enzyme by EDTA and its subsequent inactivation at 65°C. The DNase I treated samples were further purified with phenol: chloroform followed by precipitation with ice-cold ethanol (protocol I) or, alternatively, they were directly used in RT-PCR reactions (protocol II). Transcripts from ACT1, PDA1, CNA1, CNA2, TPS1 and TPS2 analyzed after each treatment showed that all mRNAs tested can be amplified if total RNA was extracted and purified after DNase I treatment, however, only TPS1, TPS2 and ACT1 mRNAs were amplified without extraction/purification step. CONCLUSION: Although more laborious and requiring a higher initial amount of material, the inclusion of an extraction and purification step allows to prepare RNA samples that are free from DNA and from low molecular contaminants and can be applied to amplify any Saccharomyces cerevisiae mRNA by RT-PCR
Reliability of Classification by Ophthalmologists with Telescreening Fundus Images for Diabetic Retinopathy and Image Quality
info:eu-repo/semantics/publishedVersio
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