48 research outputs found
Paternal obesity is associated with IGF2 hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort
- Author
- A Kerjean
- A Murrell
- A Soubry
- AD Stein
- Adelheid Soubry
- Amy Murtha
- AP Feinberg
- Autumn Bernal
- BE Levin
- BR Carone
- BT Heijmans
- C Gemma
- C Gicquel
- C Hoyo
- C Hoyo
- Cathrine Hoyo
- CC Boissonnas
- DC Dolinoy
- DC Dolinoy
- DJ Barker
- Frances Wang
- G Kaati
- GA Dunn
- GP Ravelli
- H Boerschmann
- H Cui
- H Cui
- H Cui
- J Baker
- J Frystyk
- JA McKay
- Joanne Kurtzberg
- Joellen M Schildkraut
- JS Dyer
- KJ Stothard
- LM McCowan
- M Braunschweig
- M Cruz-Correa
- M Ollikainen
- ME Pembrey
- ME Pembrey
- MJ Steenman
- MJ Sullivan
- Q Wu
- R Barres
- R Figueroa-Colon
- R Loomba
- RA Waterland
- RA Waterland
- RA Waterland
- Randy L Jirtle
- RC Painter
- RC Painter
- RL Jirtle
- RP Steegers-Theunissen
- S Honda
- S Katari
- S Pathak
- SA Tanumihardjo
- SD McDonald
- SF Ng
- SK Murphy
- SK Murphy
- SK Murphy
- SS Du Plessis
- Susan K Murphy
- W Chao
- Z Huang
- Zhiqing Huang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2013
- Field of study
Data from epidemiological and animal model studies suggest that nutrition during pregnancy may affect the health status of subsequent generations. These transgenerational effects are now being explained by disruptions at the level of the epigenetic machinery. Besides in vitro environmental exposures, the possible impact on the reprogramming of methylation profiles at imprinted genes at a much earlier time point, such as during spermatogenesis or oogenesis, has not previously been considered. In this study, our aim was to determine associations between preconceptional obesity and DNA methylation profiles in the offspring, particularly at the differentially methylated regions (DMRs) of the imprinted Insulin-like Growth Factor 2 (IGF2) gene
CD1d-Expressing Breast Cancer Cells Modulate NKT Cell-Mediated Antitumor Immunity in a Murine Model of Breast Cancer Metastasis
- Author
- A Bendelac
- AK Stanic
- BR Brinkley
- C Hong
- Chyung-Ru Wang
- D Jager
- DI Godfrey
- E Weidmann
- F Carson
- FS Kittrell
- G Eberl
- GJ Renukaradhya
- GP Dunn
- H Watarai
- HT Khong
- HY Shi
- I Algarra
- IJ Fidler
- J Cui
- J Zhou
- JA Berzofsky
- JB Reome
- JW Molling
- K Haraguchi
- K Imai
- K Tanaka
- KM Dhodapkar
- L Brossay
- Laura M. Hix
- LJ van 't Veer
- LM Coussens
- LS Metelitsa
- LS Metelitsa
- M Brigl
- M Nowak
- M Taniguchi
- M Terabe
- Ming Zhang
- MS Vincent
- MV Dhodapkar
- MV Dhodapkar
- MW Teng
- MW Teng
- NA Nagarajan
- NY Crowe
- NY Crowe
- Paul L. Stein
- PW Canchis
- QY Chen
- QY Chen
- R Cailleau
- Randy R. Brutkiewicz
- S Gross
- S Miura
- S Ramaswamy
- SC Yue
- Scott A. Coonrod
- SK Mendiratta
- T Fiedler
- T Kawano
- T Miyagi
- T Tachibana
- TJ Roberts
- V Band
- V Cerundolo
- V Shankaran
- Y Kang
- Y Li
- Y Shinkai
- YH Chiu
- Yihui H. Shi
- Z Li
- Publication venue
- Public Library of Science
- Publication date
- 13/06/2011
- Field of study
Tumor tolerance and immune suppression remain formidable obstacles to the efficacy of immunotherapies that harness the immune system to eradicate breast cancer. A novel syngeneic mouse model of breast cancer metastasis was developed in our lab to investigate mechanisms of immune regulation of breast cancer. Comparative analysis of low-metastatic vs. highly metastatic tumor cells isolated from these mice revealed several important genetic alterations related to immune control of cancer, including a significant downregulation of cd1d1 in the highly metastatic tumor cells. The cd1d1 gene in mice encodes the MHC class I-like molecule CD1d, which presents glycolipid antigens to a specialized subset of T cells known as natural killer T (NKT) cells. We hypothesize that breast cancer cells, through downregulation of CD1d and subsequent evasion of NKT-mediated antitumor immunity, gain increased potential for metastatic tumor progression.In this study, we demonstrate in a mouse model of breast cancer metastasis that tumor downregulation of CD1d inhibits iNKT-mediated antitumor immunity and promotes metastatic breast cancer progression in a CD1d-dependent manner in vitro and in vivo. Using NKT-deficient transgenic mouse models, we demonstrate important differences between type I and type II NKT cells in their ability to regulate antitumor immunity of CD1d-expressing breast tumors.The results of this study emphasize the importance of determining the CD1d expression status of the tumor when tailoring NKT-based immunotherapies for the prevention and treatment of metastatic breast cancer
The James Webb Space Telescope Mission
- Author
- Abbott Randy
- Abell James S.
- Abernathy Mark
- Abney Faith E.
- Abraham John G.
- Abraham Roberto
- Abul-Huda Yasin M.
- Acton Scott
- Adams Cynthia K.
- Adams Evan
- Adler David S.
- Adriaensen Maarten
- Aguilar Jonathan Albert
- Ahmed Mansoor
- Ahmed Nasif S.
- Ahmed Tanjira
- Alarcon Rafael Ramos
- Albat Rüdeger
- Albert Loïc
- Alberts Stacey
- Aldridge David
- Allen Mary Marsha
- Allen Shaune S.
- Altenburg Martin
- Altunc Serhat
- Alvarez Jose Lorenzo
- Ambrose Leslie L.
- Anandakrishnan Satya M.
- Andersen Gregory C.
- Anderson Harry James
- Anderson Jay
- Anderson Kristen
- Anderson Sara M.
- Aprea Julio
- Archer Benita J.
- Arenberg Jonathan W.
- Argyriou Ioannis
- Arribas Santiago
- Artigau Étienne
- Arvai Amanda Rose
- Atcheson Paul
- Atkinson Charles B.
- Averbukh Jesse
- Aymergen Cagatay
- Bacinski John J.
- Baggett Wayne E.
- Bagnasco Giorgio
- Baker Lynn L.
- Balzano Vicki Ann
- Banks Kimberly A.
- Baran David A.
- Barker Elizabeth A.
- Barrett Larry K.
- Barringer Bruce O.
- Barto Allison
- Bast William
- Baudoz Pierre
- Baum Stefi
- Beatty Thomas G.
- Beaulieu Mathilde
- Bechtold Kathryn
- Beck Tracy
- Beddard Megan M.
- Beichman Charles
- Bellagama Larry
- Bely Pierre
- Berger Timothy W.
- Bergeron Louis E.
- Bertch Maria D.
- Beskow Charlotte
- Betz Laura E.
- Biagetti Carl P.
- Birkmann Stephan
- Bjorklund Kurt F.
- Blackwood James D.
- Blazek Ronald Paul
- Blossfeld Stephen
- Bluth Marcel
- Boccaletti Anthony
- Boegner Jr. Martin E.
- Bohlin Ralph C.
- Boia John Joseph
- Bonaventura N.
- Bond Nicholas A.
- Bosley Kari Ann
- Boucarut Rene A.
- Bouchet Patrice
- Bouwman Jeroen
- Bower Gary
- Bowers Ariel S.
- Bowers Charles W.
- Boyce Leslye A.
- Boyer Christine T.
- Boyer Martha L.
- Boyer Michael
- Boyer Robert
- Bradley Larry D.
- Brady Gregory R.
- Brandl Bernhard R.
- Brannen Judith L.
- Breda David
- Bremmer Harold G.
- Brennan David
- Bresnahan Pamela A.
- Bright Stacey N.
- Broiles Brian J.
- Bromenschenkel Asa
- Brooks Brian H.
- Brooks Keira J.
- Brown Bob
- Brown Bruce
- Brown Thomas M.
- Bruce Barry W.
- Bryson Jonathan G.
- Bujanda Edwin D.
- Bullock Blake M.
- Bunker A. J.
- Bureo Rafael
- Burt Irving J.
- Bush James Aaron
- Bushouse Howard A.
- Bussman Marie C.
- Böker Torsten
- Cabaud Olivier
- Cale Steven
- Calhoon Charles D.
- Calvani Humberto
- Canipe Alicia M.
- Caputo Francis M.
- Cara Mihai
- Carey Larkin
- Case Michael Eli
- Cesari Thaddeus
- Cetorelli Lee D.
- Chance Don R.
- Chandler Lynn
- Chaney Dave
- Chapman George N.
- Charlot S.
- Chayer Pierre
- Cheezum Jeffrey I.
- Chen Bin
- Chen Christine H.
- Cherinka Brian
- Chichester Sarah C.
- Chilton Zachary S.
- Chittiraibalan Dharini
- Clampin Mark
- Clark Charles R.
- Clark Kerry W.
- Clark Stephanie M.
- Claybrooks Edward E.
- Cleveland Keith A.
- Cohen Andrew L.
- Cohen Lester M.
- Coleman Benee L.
- Colina Luis
- Colón Knicole D.
- Comber Brian J.
- Comeau Thomas M.
- Comer Thomas
- Connolly Dennis C.
- Conroy Kyle E.
- Contos Adam R.
- Contreras James
- Cook Neil J.
- Cooper James L.
- Cooper Rachel Aviva
- Correia Michael F.
- Correnti Matteo
- Cossou Christophe
- Costanza Brian F.
- Costas Maria Begoña Vila
- Coulais Alain
- Cox Colin R.
- Coyle Ray T.
- Cracraft Misty M.
- Crew Keith A.
- Curtis Gary J.
- Cusveller Bianca
- Dailey Christopher T.
- Darveau-Bernier Antoine
- Daugeron Frédéric
- Davidson Greg S.
- Davies James E.
- Davis Katherine Anne
- Davis Michael S.
- Day Ratna
- de Chambure Daniel
- de Jong Pauline
- De Marchi Guido
- De Meester Wim
- de Oliveira Catarina Alves
- Dean Bruce H.
- Decker John E.
- del Pino Bruno Rodríguez
- Delisa Amy S.
- Dell Lawrence C.
- Dellagatta Gail
- Dembinska Franciszka
- Demosthenes Sandor
- Dencheva Nadezhda M.
- Deneu Philippe
- DePriest William W.
- Deschenes Jeremy
- Dethienne Nathalie
- Detre Örs Hunor
- Diaz Rosa Izela
- Dicken Daniel
- DiFelice Audrey S.
- Dillman Matthew
- Disharoon Maureen O.
- Dixon William V.
- Doggett Jesse B.
- Dominguez Keisha L.
- Donaldson Thomas S.
- Doria-Warner Cristina M.
- Doty Heather
- Douglas Jr. Robert E.
- Doyon René
- Dressler Alan
- Driggers Jennifer
- Driggers Phillip A.
- Dunn Jamie L.
- DuPrie Kimberly C.
- Dupuis Jean
- Durning John
- Dutta Sanghamitra B.
- Earl Nicholas M.
- Eccleston Paul
- Ecobichon Pascal
- Egami Eiichi
- Ehrenwinkler Ralf
- Eisenhamer Jonathan D.
- Eisenhower Michael
- Eisenstein Daniel J.
- Elie Michelle L.
- Elliott James
- Elliott Kyle Wesley
- Engesser Michael
- Espinoza Néstor
- Etienne Odessa
- Etxaluze Mireya
- Evans Leah
- Fabreguettes Luce
- Falcolini Massimo
- Falini Patrick R.
- Fatig Curtis
- Feeney Matthew
- Feinberg Lee D.
- Fels Raymond
- Ferdous Nazma
- Ferguson Henry C.
- Ferrarese Laura
- Ferreira Marie-Héléne
- Ferruit Pierre
- Ferry Malcolm
- Filippazzo Joseph Charles
- Firre Daniel
- Fix Mees
- Flagey Nicolas
- Flanagan Kathryn A.
- Fleming Scott W.
- Florian Michael
- Flynn James R.
- Foiadelli Luca
- Fontaine Mark R.
- Fontanella Erin Marie
- Forshay Peter Randolph
- Fortner Elizabeth A.
- Fox Ori D.
- Framarini Alexandro P.
- Francisco John I.
- Franck Randy
- Franx Marijn
- Franz David E.
- Friedman Scott D.
- Friend Katheryn E.
- Frost James R.
- Fu Henry
- Fullerton Alexander W.
- Gaillard Lionel
- Galkin Sergey
- Gallagher Ben
- Galyer Anthony D.
- Gardner Jonathan P.
- Gardner Lisa E.
- Garland Dennis
- Garrett Bruce Albert
- Gasman Danny
- Gastaud René
- Gaudreau Daniel
- Gauthier Peter Timothy
- Geers Vincent
- Geithner Paul H.
- Gennaro Mario
- Gerber John
- Gereau John C.
- Giampaoli Robert
- Giardino Giovanna
- Gibbons Paul C.
- Gilbert Karolina
- Gilman Larry
- Girard Julien H.
- Giuliano Mark E.
- Gkountis Konstantinos
- Glasse Alistair
- Glassmire Kirk Zachary
- Glauser Adrian Michael
- Glazer Stuart D.
- Goldberg Joshua
- Golimowski David A.
- Gonzaga Shireen P.
- Gordon Karl D.
- Gordon Shawn J.
- Goudfrooij Paul
- Gough Michael J.
- Graham Adrian J.
- Grau Christopher M.
- Green Joel David
- Greene Gretchen R.
- Greene Thomas P.
- Greenfield Perry E.
- Greenhouse Matthew A.
- Greve Thomas R.
- Greville Edgar M.
- Grimaldi Stefano
- Groe Frank E.
- Groebner Andrew
- Grumm David M.
- Grundy Timothy
- Guillard Pierre
- Guldalian John
- Gunn Christopher A.
- Gurule Anthony
- Gutman Irvin Meyer
- Guy Paul D.
- Guyot Benjamin
- Gáspár András
- Güdel Manuel
- Hack Warren J.
- Haderlein Peter
- Hagan James B.
- Hagedorn Andria
- Hainline Kevin
- Haley Craig
- Hamel Zaky El
- Hami Maryam
- Hamilton Forrest Clifford
- Hammann Jeffrey
- Hammel Heidi B.
- Hanley Christopher J.
- Hansen Carl August
- Hardy Bruce
- Harnisch Bernd
- Harr Michael Hunter
- Harris Pamela
- Hart Jessica Ann
- Hartig George F.
- Hasan Hashima
- Hashim Kathleen Marie
- Hashimoto Ryan
- Haskins Sujee J.
- Hawkins Robert Edward
- Hayden Brian
- Hayden William L.
- Healy Mike
- Hecht Karen
- Heeg Vince J.
- Hejal Reem
- Helm Kristopher A.
- Hengemihle Nicholas J.
- Henning Thomas
- Henry Alaina
- Henry Ronald L.
- Henshaw Katherine
- Hernandez Scarlin
- Herrington Donald C.
- Heske Astrid
- Hesman Brigette Emily
- Hickey David L.
- Hilbert Bryan N.
- Hines Dean C.
- Hinz Michael R.
- Hirsch Michael
- Hitcho Robert S.
- Hodapp Klaus
- Hodge Philip E.
- Hoffman Melissa
- Holfeltz Sherie T.
- Holler Bryan Jason
- Hoppa Jennifer Rose
- Horner Scott
- Howard Joseph M.
- Howard Richard J.
- Huber Jean M.
- Hunkeler Joseph S.
- Hunter Alexander
- Hunter David Gavin
- Hurd Spencer W.
- Hurst Brendan J.
- Hutchings John B.
- Hylan Jason E.
- Ignat Luminita Ilinca
- Illingworth Garth
- Irish Sandra M.
- Isaacs III John C.
- Jackson Jr. Wallace C.
- Jaffe Daniel T.
- Jahic Jasmin
- Jahromi Amir
- Jakobsen Peter
- James Bryan
- James John C.
- James LeAndrea Rae
- Jamieson William Brian
- Jandra Raymond D.
- Jayawardhana Ray
- Jedrzejewski Robert
- Jeffers Basil S.
- Jensen Peter
- Joanne Egges
- Johns Alan T.
- Johnson Carl A.
- Johnson Eric L.
- Johnson Patricia
- Johnson Phillip Stephen
- Johnson Thomas K.
- Johnson Timothy W.
- Johnstone Doug
- Jollet Delphine
- Jones Danny P.
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- Jones Olivia C.
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- Justis Grant
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- Kaleida Catherine C.
- Kalirai Jason S.
- Kalmanson Phillip Cabrales
- Kaltenegger Lisa
- Kammerer Jens
- Kan Samuel K.
- Kanarek Graham Childs
- Kao Shaw-Hong
- Karakla Diane M.
- Karl Hermann
- Kassin Susan A.
- Kauffman David D.
- Kavanagh Patrick
- Kelley Leigh L.
- Kelly Douglas M.
- Kendrew Sarah
- Kennedy Herbert V.
- Kenny Deborah A.
- Keski-Kuha Ritva A.
- Keyes Charles D.
- Khan Ali
- Kidwell Richard C.
- Kimble Randy A.
- King James S.
- King Richard C.
- Kinzel Wayne M.
- Kirk Jeffrey R.
- Kirkpatrick Marc E.
- Klaassen Pamela
- Klingemann Lana
- Klintworth Paul U.
- Knapp Bryan Adam
- Knight Scott
- Knollenberg Perry J.
- Knutsen Daniel Mark
- Koehler Robert
- Koekemoer Anton M.
- Kofler Earl T.
- Kontson Vicki L.
- Kovacs Aiden Rose
- Kozhurina-Platais Vera
- Krause Oliver
- Kriss Gerard A.
- Krist John
- Kristoffersen Monica R.
- Krogel Claudia
- Krueger Anthony P.
- Kulp Bernard A.
- Kumari Nimisha
- Kwan Sandy W.
- Kyprianou Mark
- Labador Aurora Gadiano
- Labiano Álvaro
- Lafrenière David
- Lagage Pierre-Olivier
- Laidler Victoria G.
- Laine Benoit
- Laird Simon
- Lajoie Charles-Philippe
- Lallo Matthew D.
- Lam May Yen
- LaMassa Stephanie Marie
- Lambros Scott D.
- Lampenfield Richard Joseph
- Lander Matthew Ed
- Langston James Hutton
- Larson Kirsten
- Larson Melora
- LaVerghetta Robert Joseph
- Law David R.
- Lawrence Jon F.
- Lee David W.
- Lee Janice
- Lee Yat-Ning Paul
- Leisenring Jarron
- Leveille Michael Dunlap
- Levenson Nancy A.
- Levi Joshua S.
- Levine Marie B.
- Lewis Dan
- Lewis Jake
- Lewis Nikole
- Libralato Mattia
- Lidon Norbert
- Liebrecht Paula Louisa
- Lightsey Paul
- Lilly Simon
- Lim Frederick C.
- Lim Pey Lian
- Ling Sai-Kwong
- Link Lisa J.
- Link Miranda Nicole
- Lipinski Jamie L.
- Litten Oi In Tam
- Liu XiaoLi
- Lo Amy S.
- Lobmeyer Lynette
- Logue Ryan M.
- Long Chris A.
- Long Douglas R.
- Long Ilana D.
- Long Knox S.
- Lotz Jennifer M.
- Love-Pruitt Jennifer M.
- Lubskiy Michael
- Luers Edward B.
- Luetgens Robert A.
- Luevano Annetta J.
- Lui Sarah Marie G. Flores
- Lund III James M.
- Lundquist Ray A.
- Lunine Jonathan
- Lynch Richard J.
- López-Caniego Marcos
- Lützgendorf Nora
- MacDonald Alex J.
- MacDonald Kenneth
- Macias Matthew J.
- Maciel Cleyciane Da Costa
- Macklis Keith I.
- Maghami Peiman
- Maharaja Rishabh Y.
- Maiolino Roberto
- Makrygiannis Konstantinos G.
- Malla Sunita Giri
- Malumuth Eliot M.
- Manjavacas Elena
- Marini Andrea
- Marrione Amanda
- Marston Anthony
- Martel André R
- Martin Didier
- Martin Peter G.
- Martinez Kristin L.
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- McGregor Roy D.
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- McKay Andrew G.
- McKenzie William K.
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- McMaster Matthew
- McNeil Warren
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- Meixner Margaret
- Meléndez Marcio
- Menzel Michael P.
- Menzel Michael T.
- Merz Matthew
- Mesterharm David D.
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- Morrison Jane
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- Nieto-Santisteban Maria
- Nikolov Nikolay K.
- Nishisaka Mary Ann
- Noriega-Crespo Alberto
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- Pacifici Camilla
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- Perriello Beth A.
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- Peslier Muriel
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- Regan Michael W.
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- Rehm Kenneth D.
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- Reis Alain Conde
- Reis Carl A.
- Renk Florian
- Reoch Tom B.
- Ressler Michael
- Rest Armin W.
- Reynolds Paul J.
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- Richon Karen V.
- Ridgaway Michael
- Riedel Adric Richard
- Rieke George H.
- Rieke Marcia
- Rifelli Richard E.
- Rigby Jane R.
- Riggs Catherine S.
- Ringel Nancy J.
- Ritchie Christine E.
- Rix Hans-Walter
- Robberto Massimo
- Robinson Michael S.
- Robinson Orion
- Rock Frank W.
- Rodriguez David R.
- Roellig Thomas
- Rohrbach Scott O.
- Roman Anthony J.
- Romelfanger Frederick J.
- Romo Jr. Felipe P.
- Rosales Jose J.
- Rose Perry
- Roteliuk Anthony F.
- Roth Marc N.
- Rothwell Braden Quinn
- Rouzaud Sylvain
- Rowe Jason
- Rowlands Neil
- Roy Arpita
- Royer Pierre
- Rui Chunlei
- Rumler Peter
- Rumpl William
- Russ Melissa L.
- Ryan Michael B.
- Ryan Richard M.
- Saad Karl
- Sabata Modhumita
- Sabatino Rick
- Sabbi Elena
- Sabelhaus Phillip A.
- Sabia Stephen
- Sahu Kailash C.
- Saif Babak N.
- Salvignol Jean-Christophe
- Samara-Ratna Piyal
- Samuelson Bridget S.
- Sanders Felicia A.
- Santos Tony Dos
- Sappington Bradley
- Sargent B. A.
- Sauer Arne
- Savadkin Bruce J.
- Sawicki Marcin
- Schappell Tina M.
- Scheffer Caroline
- Scheithauer Silvia
- Scherer Ron
- Schiff Conrad
- Schlawin Everett
- Schmeitzky Olivier
- Schmitz Tyler S.
- Schmude Donald J.
- Schneider Analyn
- Schreiber Jürgen
- Schroeven-Deceuninck Hilde
- Schultz John J.
- Schwab Ryan
- Schwartz Curtis H.
- Scoccimarro Dario
- Scott John F.
- Scott Michelle B.
- Seaton Bonita L.
- Seely Bruce S.
- Seery Bernard
- Seidleck Mark
- Sembach Kenneth
- Shanahan Clare Elizabeth
- Shaughnessy Bryan
- Shaw Richard A.
- Shay Christopher Michael
- Sheehan Even
- Sheth Kartik
- Shih Hsin-Yi
- Shivaei Irene
- Siegel Noah
- Sienkiewicz Matthew G.
- Simmons Debra D.
- Simon Bernard P.
- Sirianni Marco
- Sivaramakrishnan Anand
- Slade Jeffrey E.
- Sloan G. C.
- Slocum Christine E.
- Slowinski Steven E.
- Smith Corbett T.
- Smith Eric P.
- Smith Erin C.
- Smith Koby
- Smith Robert
- Smith Stephanie J.
- Smolik John L.
- Soderblom David R.
- Sohn Sangmo Tony
- Sokol Jeff
- Sonneborn George
- Sontag Christopher D.
- Sooy Peter R.
- Soummer Remi
- Southwood Dana M.
- Spain Kay
- Sparmo Joseph
- Speer David T.
- Spencer Richard
- Sprofera Joseph D.
- Stallcup Scott S.
- Stanley Marcia K.
- Stansberry John A.
- Stark Christopher C.
- Starr Carl W.
- Stassi Diane Y.
- Steck Jane A.
- Steeley Christine D.
- Stephens Matthew A.
- Stephenson Ralph J.
- Stewart Alphonso C.
- Stiavelli Massimo
- Stockman Jr. Hervey
- Strada Paolo
- Straughn Amber N.
- Streetman Scott
- Strickland David Kendal
- Strobele Jingping F.
- Stuhlinger Martin
- Stys Jeffrey Edward
- Such Miguel
- Sukhatme Kalyani
- Sullivan Joseph F.
- Sullivan Pamela C.
- Sumner Sandra M.
- Sun Fengwu
- Sunnquist Benjamin Dale
- Swade Daryl Allen
- Swam Michael S.
- Swenton Diane F.
- Swoish Robby A.
- Tamas Laszlo
- Tao Andrew
- Taylor David K.
- Taylor Joanna M.
- Teague Kelly K.
- Telfer Randal C.
- Temim Tea
- Texter Scott C.
- Thatte Deepashri G.
- Thompson Christopher Lee
- Thompson Linda M.
- Thomson Shaun R.
- Thronson Harley
- Tierney C. M.
- Tikkanen Tuomo
- Tinnin Lee
- Tippet William Thomas
- Todd Connor William
- Tran Hien D.
- Trauger John
- Trejo Edwin Gregorio
- Truong Justin Hoang Vinh
- Tsukamoto Christine L.
- Tufail Yasir
- Tumlinson Jason
- Tustain Samuel
- Tyra Harrison
- Ubeda Leonardo
- Underwood Kelli
- Uzzo Michael A.
- Vaclavik Steven
- Valenduc Frida
- Valenti Jeff A.
- Van Campen Julie
- van de Wetering Inge
- Van Der Marel Roeland P.
- van Dishoeck Ewine F.
- van Haarlem Remy
- Van Tea Mason
- Vandenbussche Bart
- Vanterpool Dona D.
- Vernoy Michael R.
- Volk Kevin
- Voorzaat Piet
- Voyton Mark F.
- Vydra Ekaterina
- Waddy Darryl J.
- Waelkens Christoffel
- Wahlgren Glenn Michael
- Walker Jr. Frederick E.
- Wander Michel
- Warfield Christine K.
- Warner Gerald
- Wasiak Francis C.
- Wasiak Matthew F.
- Wehner James
- Weiler Kevin R.
- Weilert Mark
- Weiss Stanley B.
- Wells Martyn
- Welty Alan D.
- Wheate Lauren
- Wheeler Thomas P.
- White Christy L.
- Whitehouse Paul
- Whiteleather Jennifer Margaret
- Whitman William Russell
- Williams Christina C.
- Willmer Christopher N. A.
- Willott Chris J.
- Willoughby Scott P.
- Wilson Andrew
- Wilson Debra
- Wilson Donna V.
- Windhorst Rogier
- Wislowski Emily Christine
- Wolfe David J.
- Wolfe Michael A.
- Wolff Schuyler
- Wondel Amancio
- Woo Cindy
- Woods Robert T.
- Worden Elaine
- Workman William
- Wright Gillian S.
- Wu Carl
- Wu Chi-Rai
- Wun Dakin D.
- Wymer Kristen B.
- Yadetie Thomas
- Yan Isabelle C.
- Yang Keith C.
- Yates Kayla L.
- Yeager Christopher R.
- Yerger Ethan John
- Young Erick T.
- Young Gary
- Yu Gene
- Yu Susan
- Zak Dean S.
- Zeidler Peter
- Zepp Robert
- Zhou Julia
- Zincke Christian A.
- Zonak Stephanie
- Zondag Elisabeth
- Álvarez-Márquez Javier
- Östlin Göran
- Publication venue
- Publication date
- 10/04/2023
- Field of study
Twenty-six years ago a small committee report, building on earlier studies,
expounded a compelling and poetic vision for the future of astronomy, calling
for an infrared-optimized space telescope with an aperture of at least 4m.
With the support of their governments in the US, Europe, and Canada, 20,000
people realized that vision as the 6.5m James Webb Space Telescope. A
generation of astronomers will celebrate their accomplishments for the life of
the mission, potentially as long as 20 years, and beyond. This report and the
scientific discoveries that follow are extended thank-you notes to the 20,000
team members. The telescope is working perfectly, with much better image
quality than expected. In this and accompanying papers, we give a brief
history, describe the observatory, outline its objectives and current observing
program, and discuss the inventions and people who made it possible. We cite
detailed reports on the design and the measured performance on orbit.Comment: Accepted by PASP for the special issue on The James Webb Space
Telescope Overview, 29 pages, 4 figure
A global experiment on motivating social distancing during the COVID-19 pandemic
- Author
- Abbas Nida
- Aberson Christopher L
- Aczel Balazs
- Adamkovič Matúš
- Adamus Sylwia
- Adetula Adeyemi
- Adetula Gabriel Agboola
- Adiguzel Arca
- Adoric Vera Cubela
- Afhami Reza
- Agadullina Elena
- Ahlgren Lina
- Ahmed Afroja
- Ahn El Rim
- Akkas Handan
- Akter Shahunur
- Albayrak-Aydemir Nihan
- Allred Tara Bulut
- Almeida Inês AT
- Alvarez Daniela Serrato
- Alves Sara G
- Anjum Gulnaz
- Ankushev Vladislav
- Anne Michele
- Antazo Benedict
- Antfolk Jan
- Anton-Boicuk Lisa
- Antoniadi Maria
- Antwerpen Natasha van
- ARABI Kanza AITEL
- Arinze Azuka Ikechukwu
- Arinze Nwadiogo Chisom
- Arriaga Patricia
- Aruta John Jamir Benzon
- Arvanitis Alexios
- Askelund Adrian Dahl
- Atari Mohammad
- Azab Habiba
- Azevedo Flavio
- Azouaghe Soufian
- Babinčák Peter
- Bai Hui
- Baklanova Ekaterina
- Balci Busra Bahar
- Ballantyne Tonia
- Banik Gabriel
- Barkoukis Vassilis
- Barzykowski Krystian
- Baskin Ernest
- Basnight-Brown Dana M
- Batres Carlota
- Bavolar Jozef
- Bayyat Manal M
- Beatrix Labadi
- Beaudry Jennifer L
- Becker Maja
- Behzadnia Behzad
- Beitner Julia
- Belaus Anabel
- Benka Jozef
- Berkessel Jana B
- Bernardo Márcia
- Beshears Julie E
- Betlehem Ruben
- Bialek Michal
- Bialobrzeska Olga
- Biberauer Theresa
- Bijlstra Gijsbert
- Bogatyreva Natalia
- Bokkour Ahmed
- Boller Daniel
- Bosch Jasmijn
- Bosma Minke Jasmijn
- Boucher Leanne
- Boudesseul Jordane
- Bozdoc Andreea Ioana
- Bradford Maria
- Bradshaw Emma L
- Bran Alexandre
- Bravo Olalla Niño
- Brohmer Hilmar
- Brownlow Charlotte
- Buchanan Erin M
- Bundt Carsten
- Butt Muhammad Mussaffa
- Bylinina Lisa
- Calin-Jageman Robert J
- Campos Olatz
- Capizzi Mariagrazia
- Carpentier Joelle
- Ceary Chris D
- Cellini Nicola
- Chakarova Desislava
- Chanal Julien
- Chartier Christopher R
- Charyate Abdelilah Ca
- Chen Sau-Chin
- Chen Zhang
- Chiu Faith
- Chopik William J
- Chou Wei-Lun
- Chuan-Peng Hu
- Cocco Beatrice
- Cohen Noga
- Coles Nicholas A
- Collins W Matthew
- Colloff Melissa F
- Corral-Frías Nadia S
- Correa Pablo Sebastián
- Correia Rita C
- Costa Sebastiano
- Cruz Vásquez Julio E
- Cyrus-Lai Wilson
- Czamanski-Cohen Johanna
- Czarnek Gabriela
- Cárcamo Rodrigo A
- Daches Shimrit
- Dalgar Ilker
- Damnjanović Kaja
- Davis William E
- De la Rosa-Gomez Anabel
- Delgado Lady Grey Javela
- DePaola Chloe
- Desai Kermeka
- Dimova Daliborka
- Dixson Barnaby James Wyld
- Djamai Ikhlas
- Djordjevic Jasna Milosevic
- Domurat Artur
- Doren Natalia Van
- Drexler Shira Meir
- Du Hongfei
- Du Xinkai
- Dubrov Dmitrii
- Dujols Olivier
- Dunleavy Daniel
- Dunn Megan R
- Dursun Pinar
- Ebersole Charles R
- Emmanuel Agesin Bamikole B
- Espinoza Barría Mauricio F
- Esteban-Serna Celia
- Etebari Zahra
- Eudave Luis
- Evans Kortnee
- FatahModares Saeideh
- Fedotov Maksim
- Feldman Gilad
- Ferguson Lisa J
- Ferreira Ana
- Ferreyra Cecilia
- Filip Katarzyna
- Findor Andrej
- Flowe Heather
- Forbes Paul AG
- Forest Jacques
- Foroni Francesco
- Forscher Patrick S
- Frias-Armenta Martha
- Friedemann Maja
- Frizzo Thomas
- Fu Cynthia HY
- Galindo-Caballero Oscar J
- Garcia Elkin Oswaldo Luis
- Gargurevich Rafael
- Geiger Sandra J
- Geniole Shawn N
- Gialitaki Zoi
- Gill Tripat
- Gjoneska Biljana
- Godbersen Hendrik
- Gourdon-Kanhukamwe Amélie
- Grano Caterina
- Greenburgh Anna
- Grigoryev Dmitry
- Grinberg Maurice
- Groyecka-Bernard Agata
- Grzech Karolina
- Gugliandolo Maria C
- Gunton Lesley-Ann
- Habib Sumaiya
- Habte Redeate
- Hajdu Nandor
- Hanel Paul HP
- Hartanto Andree
- Harutyunyan Mikayel
- Hassan Widad
- Hedgebeth Mattie V
- Hernandez Alejandrina
- Herrera Dora
- Hofer Gabriela
- Holford Dawn Liu
- Hostler Thomas J
- House Thea
- Houston Ralph
- Hoyer Karlijn
- Hricova Monika
- Hristova Evgeniya
- Hruška Matej
- Hubena Barbora
- Ihaya Keiko
- IJzerman Hans
- Isager Peder Mortvedt
- Ishii Tatsunori
- Ishkhanyan Byurakn
- Ivanov Aleksandr
- Iyer Aishwarya
- Izquierdo Sara Morales
- Jackson Emily A
- Jaeger Bastian
- Jai-ai Rachadaporn
- Janak Allison
- Jang Yuna
- Janjić Kristina
- Jansen Martine
- Janssen Steve MJ
- Jaremka Lisa M
- Jernsäther Teodor
- Jiang Xiaoming
- Jimenez-Leal William
- Johannes Niklas
- Jones Marc V
- Joy-Gaba Jennifer A
- Jurković Anita Penić
- Kabir Muhib
- Kadreva Veselina Hristova
- Kaliska Lada
- Kamburidis Julia
- Kaminski Gwenael
- Kappes Heather Barry
- Karaarslan Cemre
- Karababa Alper
- Karashiali Christiana
- Karekla Maria
- Kassianos Angelos P
- Kačmár Pavol
- Khaobunmasiri Sirikon
- Khaoudi Ahmed
- Khosla Meetu
- Khumkom Sakda
- Kielińska Julita
- Kirgizova Komila
- Kiselnikova Natalia
- Klevjer Kristoffer
- Kocalar Halil Emre
- Koehn Monica A
- Kohlová Markéta Braun
- Koptjevskaja-Tamm Maria
- Korbmacher Max
- Korobova Tatiana
- Kossowska Małgorzata
- Kovic Vanja
- Kowal Marta
- Kozma Luca
- Krafnick Anthony J
- Križanić Valerija
- Krupić Dajana
- Krupić Dino
- Kung Franki YH
- Kunisato Yoshihiko
- Kunst Jonas R
- Kurfali Merve A
- Kurfalı Murathan
- Kushnir Elizaveta
- Kuzminska Anna O
- Kácha Ondřej
- Lamm Claus
- Landry Anais Thibault
- Law Wilbert
- Lazarevic Ljiljana B
- Lee Jeong Min
- Legate Nicole
- Legault Lisa
- Lerche Veronika
- Levine Shelby L
- Levitan Carmel A
- Levy Neil
- Lewis David MG
- Lewis Savannah
- Li Manyu
- Li Ranran
- Liga Francesca
- Lima Tiago JS
- Lin Yijun
- Lins de Holanda Coelho Gabriel
- Lins Samuel
- Lu Jackson G
- Lucas Marc Y
- Lund Maria Louise
- Luxon Alexandria M
- Macapagal Paulo Manuel
- Machin Michael A
- Machin Tanya
- Magrin Maria Elena
- Majeed Nadyanna M
- Maldonado Mónica Alarcón
- Mallik Peter R
- Manavalan Mathi
- Maniaci Michael R
- Manley Harry
- Manunta Efisio
- Marcu Gabriela Mariana
- Marinova Evelina
- Marko Dafne
- Marszalek Magdalena
- Martela Frank
- Martin Neil I
- Martončik Marcel
- Massoni Sébastien
- Matos Lennia
- Maturan Princess Lovella G
- McCarthy Randy
- Mensink Michael C
- Messerschmidt Johanna
- Metin-Orta Irem
- Metz Molly A
- Micheli Leticia
- Miller Jeremy K
- Mioni Giovanna
- Miranda Jacob F
- Misiak Michal
- Modena Arianna
- Mokady Aviv
- Mola Débora
- Moller Arlen
- Monajem Arash
- Monteiro Renan P
- Moon Karis
- Morbée Sofie
- Moreau David
- Morris Katherine
- Mosannenzadeh Farnaz
- Moshontz Hannah
- Moss Jennifer D
- Muchembled Fany
- Muda Rafał
- Muminov Abdumalik
- Musser Erica
- Nadif Khaoula
- Ndukaihe Izuchukwu LG
- Nedelcheva-Datsova Mina
- Neubauer Andreas B
- Ngyuen Thuy-vy
- Nicolotti Matilde
- Niemiec Christopher P
- Nilsonne Gustav
- Nock Nora L
- Noone Chris
- Norton James O
- Ntoumanis Nikos
- Ogbonnaya Chisom Esther
- Oliveira Raquel
- Olofsson Jonas K
- Onie Sandersan
- Oosterlinck Marlies
- Ordoñez-Riaño Santiago
- Ortiz Manuel S
- Ostermann Thomas
- Ouherrou Nihal
- Overkott Clara
- Ozery Daphna Hausman
- Očovaj Sanja Batić
- Paltrow Tamar
- Pantazi Myrto
- Papachristopoulos Konstantinos
- Papadatou-Pastou Marietta
- Parashar Neha
- Paris Bastien
- Paruzel-Czachura Mariola
- Parzuchowski Michal
- Pavlacic Jeffrey M
- Perillo Jennifer T
- Pfuhl Gerit
- Picciocchi Chiara
- Pickering Jade S
- Pilato Alice
- Pineda Lina Maria Sanabria
- Pinto Isabel
- Pit Ilse L
- Popović Dora
- Pourafshari Razieh
- Primbs Maximilian A
- Pronizius Ekaterina
- Prusova Irina
- Pérez Laura Calderón
- Pöntinen Sara
- Quested Eleanor
- Rachev Nikolay R
- Radtke Theda
- Rahal Rima-Maria
- Rahman Tasnim
- Rana Kafeel
- Reeck Crystal
- Reggev Niv
- Reips Ulf-Dietrich
- Ren Dongning
- Rentzelas Panagiotis
- Reyna Cecilia
- Ribeiro Matheus Fernando Felix
- Ribeiro Rafael R
- Ricaurte Danilo Zambrano
- Richard Karley L
- Rivera María del Carmen MC Tejada
- Roczniewska Marta
- Rojas-Berscia Luis Miguel
- Romanova Marina
- Ropovik Ivan
- Rosa Anna Dalla
- Ross Robert M
- Rothbaum Alex O
- Roxas Jose Carlos T
- Ruiz-Fernández Susana
- Ryan Richard M
- Ryan William S
- Röer Jan Philipp
- Sabristov Marina
- Sacakli Asli
- Samojlenko Lara
- Santos Anabela Caetano
- Sarieva Irena
- Sarioguz Eylul
- Say Nicolas
- Schei Vidar
- Schmidt Kathleen
- Schmidt Nadya-Daniela
- Schrötter Jana
- Schulenberg Stefan E
- Searston Rachel
- Seehuus Martin
- Sharifian MohammadHasan
- Shi Jiaxin
- Silan Miguel A
- Silva Jaime R
- Simonovic Nicolle
- Singer Gage
- Singh Anisha
- Sinkolova Sladjana
- Sirota Miroslav
- Skowronek Anna
- Smit Eline Suzanne
- Soenens Bart
- Solas Sara Álvarez
- Solorzano Claudio Singh
- Song Xin
- Sorokowska Agnieszka
- Sorokowski Piotr
- Soto José A
- Sousa Daniela
- Standage Martyn
- Staniaszek Karolina
- Stephen Ian D
- Stieger Stefan
- Stojanovska Dragana
- Stojanovska Marija
- Storage Daniel
- Stoyanova Alina
- Studzinska Anna
- Suchow Jordan W
- Sula Isabela
- Sunami Naoyuki
- Suter Lilian
- Sutherland Clare AM
- Sverdrup Therese E
- Szabelska Anna
- Szala Anna
- Szaszi Barnabas
- Szwed Paulina
- Taber Jennifer
- Tajchman Zuzanna
- Tamnes Christian K
- Tatachari Srinivasan
- Terskova Maria
- Theodoropoulou Andriana
- Thogersen-Ntoumani Cecilie
- Thomas Andrew G
- Thommesen Katrine Krabbe
- Todsen Anna Louise
- Topor Marta
- Toro Mónica
- Torres Adriana Olaya
- Torunsky Nathan
- Tran Ulrich S
- Travaglino Giovanni A
- Tshonda Sarah Suzette
- Tullett Alexa M
- Tümer Murat
- Unanue Wenceslao
- Urban Jan
- Urooj Anum
- Urriago-Rayo Joan
- Urry Heather L
- Uttley Jim
- Vaidis David C
- Valentova Jaroslava Varella
- Vally Zahir
- van Hooff Madelon LM
- van Schie Kevin
- van Steenkiste IMM
- Vansteenkiste Maarten
- Varella Marco AC
- Vargas-Nieto Juan Camilo
- Vasilev Martin R
- Vaughn Leigh Ann
- Vdovic Milica
- Vega Diego
- Verbruggen Frederick
- Verharen Jeroen PH
- Vermote Branko J
- Vezirian Kevin
- Victoria Ortiz María
- Vieira Luc
- Vilar Roosevelt
- Vilares Iris
- Vilsmeier Johannes K
- Vintr Jáchym
- Volz Leonhard
- von Bastian Claudia C
- von Bormann Suparpit M
- Voracek Martin
- Vranka Marek
- Vračar Selena
- Wachowicz Jakub
- Wajanatinapart Piyaorn
- Walczak Radoslaw B
- Wang Chunhui
- Warmelink Lara
- Waterschoot Joachim
- Weinstein Netta
- Westerlund Minja
- Westgate Erin C
- Whitt Cassie M
- Wichman Aaron L
- Wielgus Magdalena
- Willis Megan
- Wilson John Paul
- Wolfe Kelly
- Wylie Keith
- Xiao Qinyu
- Yamada Yuki
- Yao Elvin
- Yeung Siu Kit
- Yu Karen
- Zakharov Ilya
- Zdybek Przemysław
- Ziano Ignazio
- Zickfeld Janis
- Zorjan Saša
- Zrimsek Miha
- Zsido Andras N
- Çoksan Sami
- Özdoğru Asil Ali
- Čadek Martin
- Šakan Dušana
- Štrukelj Eva
- Žuro Barbara
- Publication venue
- 'Proceedings of the National Academy of Sciences'
- Publication date
- 27/05/2022
- Field of study
Finding communication strategies that effectively motivate social distancing continues to be a global public health priority during the COVID-19 pandemic. This cross-country, preregistered experiment (n = 25,718 from 89 countries) tested hypotheses concerning generalizable positive and negative outcomes of social distancing messages that promoted personal agency and reflective choices (i.e., an autonomy-supportive message) or were restrictive and shaming (i.e., a controlling message) compared with no message at all. Results partially supported experimental hypotheses in that the controlling message increased controlled motivation (a poorly internalized form of motivation relying on shame, guilt, and fear of social consequences) relative to no message. On the other hand, the autonomy-supportive message lowered feelings of defiance compared with the controlling message, but the controlling message did not differ from receiving no message at all. Unexpectedly, messages did not influence autonomous motivation (a highly internalized form of motivation relying on one’s core values) or behavioral intentions. Results supported hypothesized associations between people’s existing autonomous and controlled motivations and self-reported behavioral intentions to engage in social distancing. Controlled motivation was associated with more defiance and less long-term behavioral intention to engage in social distancing, whereas autonomous motivation was associated with less defiance and more short- and long-term intentions to social distance. Overall, this work highlights the potential harm of using shaming and pressuring language in public health communication, with implications for the current and future global health challenges
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
- Allen Thaddeus
- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
- Ambrose Karen
- Ambrose Kerrie
- Amemiya Chris
- Amico-Keller Gina
- Amin Amita G.
- Anderson Mechele
- Anderson Scott
- Anderson Scott
- Andora Janice
- Andredesz Carol
- Andrew Robert
- Andrews Dan
- Andrews Daniel
- Andrews Neil
- Andrews Stephanie
- Andriese Tim
- Anthouard Véronique
- Antonarakis Stylianos E.
- Anyalebechi Vivian
- Aoki Norie
- Apostolou Sinoula
- Apweiler Eva
- Arachchi Harindra
- Arai Rie
- Arbery Hazel
- Arcaina Marlon
- Arcaina Terisita
- Archer Beth
- Arellano Andre
- Arellano-Jones Perry
- Armbruster Jeff
- Armstrong Jon
- Arredondo Dilrukshi P.
- Arredondo Heather Hope
- Artiguenave François
- Asakawa Shuichi
- Asakawa Teruyo
- Ash Gareth
- Ashcroft Kevin
- Ashurst Jennifer
- Ashwell Robert
- Ashworth Linda K.
- Aslanidis Cara
- Asomugha Chinwe O.
- Asuncion Lawreen
- Atkin Deborah
- Atkinson Andrea
- Atkinson Barry
- Attix Cristina
- Attwood John
- Aubin Keith
- Auger Katherine
- Austin Shannon Michelle
- Avila Aaron
- Avis Terry
- Ayele Mulu
- Babayan Primo
- Babbage Anne
- Babbage Sarah
- Bach Phil
- Bachatsang Pasang
- Bacon Joanne
- Badri Hummy
- Baertsch Robert
- Bagguley Claire
- Bailey Jonathan
- Bajorek Eva
- Baker Andrew
- Baker Dan
- Baker M.
- Baker Richard
- Bakis Michele
- Baldwin Jennifer
- Banda Michael
- Banerjee Ruby
- Bao Jingyue
- Bao Qiyu
- Bao Weidong
- Bao Weidong
- Baptiste Pertrice
- Barbaria Joseph A.
- Barbe Valérie
- Bardill Simon
- Barker Daniel
- Barker Darren
- Barker Gary
- Barlow Karen
- Baron Laurent
- Barrett Anika
- Bartlett Rebecca
- Basham Victoria
- Bashman David
- Basu Suba
- Bateman Alex
- Bates Karen
- Battles John
- Batzer Mark
- Baumgart Cornelia
- Baumohl Jason
- Baynes Caroline
- Bayul Tashi
- Beall Keith
- Beard Lisa
- Beard Susan
- Beare David
- Beasley Alastair
- Beasley Helen
- Beasley Oliver
- Beaucham Leslie
- Beaudet Arthur
- Beck Alfred
- Beck Stephen
- Becker Michael
- Bell Emma
- Bell George I.
- Bellard Terell M.
- Bellerby Damian
- Bellerby Tristram
- Belter Edward A., Jr.
- Bemrose Richard
- Benard Michael Anthony
- BenKahla Alia
- Benke J
- Benner William
- Bennett James
- Bensasson Douda
- Bentley Andrew
- Bentley Dan
- Bentley David
- Berardinis Véronique de
- Bercovitz John
- Berghoff Amy
- Bergmann Anne
- Berkowicz Nicolas
- Berks Mary
- Berks Michael
- Bethel Graeme
- Beugelsdijk Tony J.
- Bhakta Rita
- Bhuchar Venita
- Bi Shihua
- Bian Xuemeng
- Bieri Tamberlyn
- Bimage Kesha E.
- Bird Christine
- Birditt Brian
- Birney Ewan
- Birney Ewan
- Birren Bruce
- Bissell Helen
- Biswalo Kaneza
- Bituin Aleksandr
- Black Stacey
- Blackburne-Maze Suzanne
- Blair Jessica Anne
- Blakey Sarah
- Blanks Tia
- Blasiar Darin
- Blazej Robert
- Blitshsteyn Berta
- Blomstrom David B.
- Bloom Scott
- Bloom Toby
- Blumer Heather
- Blye Jason
- Blyth Peter R.
- Blöcker Helmut
- Boatright Elizabeth
- Boehm John
- Boen Juanan
- Boguslavskiy Leonid
- Bolton Christel
- Bolund Lars
- Bondoc Marnel
- Bonfield James
- Bonnett Ralph
- Bonnin David
- Border Richard
- Borowsky Mark
- Borzym Katja
- Boukhgalter Boris
- Bowen Eric
- Bradley Amanda
- Bradshaw-Cordum Holly
- Brady Nicola
- Brandriff Brigitte F.
- Brannon Wade
- Branscomb Elbert
- Bray Jason
- Bray-Allen Sarah
- Brettin Thomas
- Bridgeman Anne
- Bridgers Michael
- Brimhall Angela K.
- Brokstein Peter
- Brook Jonathan
- Brooking Shane
- Brottier Philippe
- Brown Andrew
- Brown Clive
- Brown Jacqui
- Brown Margaret
- Brown Mary
- Brown Mary J.
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- Brown Nancy C.
- Bruce David D.
- Bruce Robert
- Bruno William J.
- Bruskiewich Richard
- Bryant Jackie
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- Buatsi Delali
- Buck David
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- Donlin Jeremy E.
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- Kruchowski Scott S.
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- Zainoun Joanne
- Zembeck Lisa
- Zeng Yixin
- Zhai Dong
- Zhan Guoping
- Zhang Bo
- Zhang Caimin
- Zhang Fengmei
- Zhang Guangyu
- Zhang Guohua
- Zhang Guohua
- Zhang Haiqing
- Zhang Haiqing
- Zhang Haiqing
- Zhang Hongbo
- Zhang Hongbo
- Zhang Jingjing
- Zhang Jingjing
- Zhang Jingkun
- Zhang Jiuchun
- Zhang Jiuchun
- Zhang Lanzhi
- Zhang Li
- Zhang Li
- Zhang Meihua
- Zhang Meng
- Zhang Ming
- Zhang Qing
- Zhang Ruhua
- Zhang Shaojie
- Zhang Tiezhen
- Zhang Wei
- Zhang Wei
- Zhang Xianglin
- Zhang Xianglin
- Zhang Xiaoliang
- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Determining crystal structures through crowdsourcing and coursework
- Author
- Agnes Tymieniecki
- Ahmet Caglar
- Alan Coral
- Alexis Lawton
- Alice Elizabeth Jensen
- Allen Lubow
- Amanda A. Winburn
- Amanda Boitano
- Amanda Ruesch
- Amy Elizabeth Lisle
- Andrew P. Sikkema
- Andrew T. Maxwell
- Anjali Sundar
- Anna-Lisa Lawrence
- Annes Yukyung Kim
- Antara Afrin
- Barb Failer
- Bartosz Kaszubowski
- Bhargavi Maheshwer
- Bilal Turfe
- Bohdan Hrytsiv
- Brancaccio Vincenzo
- Breno Renan de Melo Cruz
- Brian Joseph McManus
- Brian Koepnick
- Bruno Kestemont
- Carl Vardeman
- Casey Comisky
- Catherine Neilson
- Catherine R. Landers
- Christian Huebner
- Christopher Ince
- Courtney Elizabeth Killeen
- Dalia Antebi-Lerrman
- Daniel Jon Buske
- Daniel Totonjian
- Danny Luan
- David Baker
- David Marshall Copeland
- David Murray
- David S. Rogawski
- Dawid Jagieła
- Derek Wolfe
- Dietmar Janz
- Douglas C. Wheeler
- Duc Pham
- Elaina Michewicz
- Elie Cali
- Elizabeth Hull
- Emily Pardington
- Emmanuel Croze
- Farah Rezae
- Felix R. M. Beinlich
- Finn P. Maloney
- Firas Khatib
- Floyd Orville Martin
- Galal Osama Galal
- Gil Beecher
- Grace Chen
- Grace Sun
- Guido Alexander de Jong
- Guy Ykman
- Halie E. Anderson
- Harald Feldmann
- Hugo Paul Perez Chan
- Istvan Kovanecz
- Ivan Vasilchenko
- James C. A. Bardwell
- James C. Connellan
- Jami Lynne Borman
- Jane Chang
- Jane Norrgard
- Jebbie Kanfer
- Jeff Flatten
- Jeffrey M. Canfield
- Jeffrey Thomas Hewlett
- Jennifer Sterbenz
- Jesse David Slone
- Jiho Lim
- Jimmy Oh
- Joanne Mitchell
- John Bishop
- John Douglas Kroeger
- Jonas Schinkler
- Joseph McLaughlin
- Joshua Morof
- June M. Brownlee
- Junho Lee
- Justin Bell
- Juyoung Samuel Inn
- Kaitlin Hahm
- Kaitlin Roth
- Karl Willem Fellbaum
- Karun Nair
- Katherine Markin
- Kathleen Harper
- Katie Schramm
- Kevin Toni Eid
- Kirk J. Abbey
- Kristina Gam
- Lennart E. Isaksson
- Linda Wei
- Lisa N. Cummins
- Lisha Murphy
- Logan S. Ahlstrom
- Lori Anne Miller
- Lucy Yuan
- Lulia Kana
- Lyn Bain
- Lynn Carpenter
- Lynn Daboul
- Maarten Desnouck
- Manasa G. Sharma
- Marcus Belcastro
- Mario Karam Shammas
- Martin Szew
- Martin Szew
- Matthew Britton
- Matthew R. Chapman
- Matthias Gaebel
- Max Chason
- Max Power
- Meredith A. Skiba
- Michael Cassidy
- Michael Pfützenreuter
- Michele Minett
- Michiel Wesselingh
- Minjune Yi
- Moaz Sinan
- Neha Jain
- Neil Haydn Tormey Cameron
- Nicholas Andrew Tooley
- Nicholas I. Bolibruch
- Nicole M. Koropatkin
- Nisha Korakavi
- Noah Benevides
- Norah Kathleen Kerr
- Nova Barlow
- null null
- null null
- Nykole Krystyne Crevits
- Patrick Comer
- Paul Dunn
- Paulo Sergio Silveira Belo Nascimen Roque
- Peter Riber
- Petri Pikkanen
- Philipp Koldewey
- Pragya Magur
- Quresh Savliwala
- Raafay Shehzad
- Randy Viosca
- Raoul Martin
- Reid Michael Davison
- Robert James Fraser
- Robert Leduc
- Roman Madala
- Roshun Rajiv Sankaran
- Sam Lee
- Saule Tamkus
- Scott Horowitz
- Scott Shnider
- Seth Cooper
- Sharon de Boisblanc
- Shirley Chen
- Sho Harvey
- Sin Ye Hwang
- Slava Butkovich
- Sohrab Vatsia
- Spencer Bliven
- Stefan Withrow
- Stephen Hettler
- Stephen Telehany
- Steven A. Schwegmann
- Steven Parkes
- Susan C. Kleinfelter
- Sven Michael Holst
- T. J. A. van der Laan
- Tahra K Luther
- Taylor Manett
- Thomas Bausewein
- Thomas James Johnson
- Timothy Ryan Brash
- Tsinatkeab T. Hailu
- Vera Simon
- Warwick Pulley
- William Hull
- Wyatt Kuhlman
- Yeonjung Park
- Zoran Popović
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
We show here that computer game players can build high-quality crystal structures. Introduction of a new feature into the computer game Foldit allows players to build and real-space refine structures into electron density maps. To assess the usefulness of this feature, we held a crystallographic model-building competition between trained crystallographers, undergraduate students, Foldit players and automatic model-building algorithms. After removal of disordered residues, a team of Foldit players achieved the most accurate structure. Analysing the target protein of the competition, YPL067C, uncovered a new family of histidine triad proteins apparently involved in the prevention of amyloid toxicity. From this study, we conclude that crystallographers can utilize crowdsourcing to interpret electron density information and to produce structure solutions of the highest quality
A global experiment on motivating social distancing during the COVID-19 pandemic
- Author
- Abbas N.
- Aberson C.
- Aczel B.
- Adamkovič M.
- Adamus Sylwia
- Adetula A.
- Adetula G. A.
- Adiguzel A.
- Afhami Reza
- Agadullina E.
- Agesin B. B.
- Ahlgren L.
- Ahmed A.
- Ahn E. R.
- Akkas H.
- Akter Shahunur
- Alarcón Maldonado M.
- Albayrak-Aydemir N.
- Almeida I. A. T.
- Alves Sara G.
- Anjum G.
- Ankushev Vladislav
- Anne M.
- Antazo B.
- Antfolk J.
- Anton-Boicuk L.
- Antoniadi M.
- Arinze A. I.
- Arinze N. C.
- Arriaga Patricia
- Aruta J. J. B.
- Arvanitis A.
- Askelund A. D.
- Atari M.
- Azab H.
- Azevedo F.
- Azouaghe Soufian
- Babinčák P.
- Bai H.
- Baklanova E.
- Balci B. B.
- Ballantyne Tonia
- Banik G.
- Barkoukis V.
- Barzykowski K.
- Baskin E.
- Basnight-Brown D. M.
- Batić Očovaj Sanja
- Batres C.
- Bavolar J.
- Bayyat M. M.
- Beatrix L.
- Beaudry J. L.
- Becker M.
- Behzadnia B.
- Beitner J.
- Belaus A.
- Benka J.
- Berkessel J. B.
- Bernardo Márcia
- Beshears J. E.
- Betlehem Ruben
- Bialek M.
- Bialobrzeska O.
- Biberauer Theresa
- Bijlstra G.
- Bogatyreva N.
- Bokkour A.
- Boller D.
- Bosch J.
- Bosma M. J.
- Boucher L.
- Boudesseul J.
- Bozdoc A. I.
- Bradford M.
- Bradshaw E. L.
- Bran A.
- Braun Kohlová M.
- Bravo Olalla Niño
- Brohmer H.
- Brownlow C.
- Buchanan E. M.
- Bulut Allred T.
- Bundt C.
- Bylinina L.
- Caetano Santos A.
- Calderón Pérez L.
- Calin-Jageman Robert J.
- Campos Olatz
- Capizzi M.
- Carpentier J.
- Ceary Chris D.
- Cellini N.
- Chakarova D.
- Chanal J.
- Chartier C. R.
- Charyate A. C. A.
- Chen Sau-Chin
- Chen Zhang
- Chiu F.
- Chopik W. J.
- Chou W.
- Chuan-Peng H.
- Cocco B.
- Cohen N.
- Coles N. A.
- Collins W. Matthew
- Colloff M. F.
- Corral-Frías N. S.
- Correa Pablo Sebastián
- Correia R. C.
- Costa Sebastiano
- Cruz Vásquez J.E.
- Cubela Adoric Vera
- Cyrus-Lai Wilson
- Czamanski-Cohen J.
- Czarnek G.
- Cárcamo Rodrigo A.
- Daches Shimrit
- Dalgar I.
- Dalla Rosa A.
- Damnjanović K.
- David W. E.
- De la Rosa-Gomez A.
- DePaola Chloe
- Desai K.
- Dimova D.
- Dixson B. J. W.
- Djamai I.
- Domurat A.
- Drexler Shira Meir
- Du H.
- Du Xinkai
- Dubrov D.
- Dujols O.
- Dunleavy D.
- Dunn M.
- Dursun P.
- Ebersole C. R.
- El Arabi K. A.
- Elvin Yao
- Espinoza Barría M. F.
- Esteban-Serna C.
- Etebari Z.
- Eudave L.
- Evans K.
- FatahModares Saeideh
- Fedotov Maksim
- Feldman G.
- Ferguson L. J.
- Ferreira A.
- Ferreyra C.
- Filip K.
- Findor A.
- Flowe H.
- Forbes Paul A. G.
- Forest J.
- Foroni F.
- Forscher P. S.
- Frias-Armenta M.
- Friedemann M.
- Frizzo Thomas
- Fu C. H. Y.
- Galindo-Caballero Oscar J.
- Garcia E. O. L.
- Gargurevich Rafael
- Geiger Sandra J.
- Geniole Shawn N.
- Gialitaki Zoi
- Gill Tripat
- Gjoneska B.
- Godbersen H.
- Gourdon-Kanhukamwe A.
- Grano C.
- Greenburgh A.
- Grigoryev Dmitry
- Grinberg M.
- Groyecka-Bernard A.
- Grzech K.
- Gugliandolo M. C.
- Gunton L.
- Habib Sumaiya
- Habte Redeate
- Hajdu N.
- Hanel Paul H. P.
- Hartanto A.
- Harutyunyan M.
- Hassan Widad
- Hausman Ozery D.
- Hedgebeth M. V.
- Hernandez A.
- Herrera D.
- Hofer G.
- Holford D. L.
- Hostler Thomas J.
- House Thea
- Houston Ralph
- Hoyer K.
- Hricova M.
- Hristova E.
- Hruška M.
- Hubena B.
- Ihaya K.
- IJzerman H.
- Isager Peder Mortvedt
- Ishii Tatsunori
- Ishkhanyan B.
- Ivanov A.
- Iyer A.
- Jackson E. A.
- Jaeger B.
- Jai-ai Rachadaporn
- Janak A.
- Jang Yuna
- Janjić K.
- Jansen M.
- Janssen Steve M. J.
- Jaremka L. M.
- Javela Delgado L. G.
- Jernsäther Teodor
- Jiang Xiaoming
- Jimenez-Leal William
- Johannes N.
- Jones M. V.
- Joy-Gaba J. A.
- Jurković A. P.
- Kabir M.
- Kadreva Veselina Hristova
- Kaliska L.
- Kamburidis J.
- Kaminski G.
- Kappes H. B.
- Karaarslan C.
- Karababa A.
- Karashiali C.
- Karekla M.
- Kassianos A. P.
- Kačmár Pavol
- Khaobunmasiri S.
- Khaoudi A.
- Khosla M.
- Khumkom Sakda
- Kielińska J.
- Kirgizova K.
- Kiselnikova N.
- Klevjer K.
- Kocalar H. E.
- Koehn M. A.
- Koptjevskaja-Tamm Maria
- Korbmacher M.
- Korobova T.
- Kossowska M.
- Kovic Vanja
- Kowal M.
- Kozma L.
- Krabbe Thommesen K.
- Krafnick A. J.
- Križanić Valerija
- Krupić D.
- Krupić D.
- Kung F. Y. H.
- Kunisato Yoshihiko
- Kunst J. R.
- Kurfali M.
- Kurfali M.
- Kushnir E.
- Kuzminska A. O.
- Kácha Ondřej
- Lamm C.
- Law Wilbert
- Lazarevic L. B.
- Lee J. M.
- Legate Nicole
- Legault Lisa
- Lerche Veronika
- Levine Shelby L.
- Levitan C. A.
- Levy N.
- Lewis D. M. G.
- Lewis Savannah
- Li M.
- Li R.
- Liga F.
- Lima Tiago J. S.
- Lin Yijun
- Lins de Holanda Coelho G.
- Lins Samuel
- Lu J. G.
- Lucas M. Y.
- Lund M. L.
- Luxon A. M.
- Maarten V.
- Macapagal Paulo Manuel
- Machin Michael A.
- Machin Tanya
- Magrin M. E.
- Majeed N. M.
- Mallik P. R.
- Manavalan M.
- Maniaci Michael R.
- Manley H.
- Manunta E.
- Marcu G. M.
- Marinova E.
- Marko D.
- Marszalek M.
- Martela F.
- Martin N. I.
- Martončik M.
- Massoni Sébastien
- Matos L.
- Maturan Princess Lovella G.
- McCarthy Randy
- Mensink M. C.
- Messerschmidt J.
- Metin-Orta I.
- Metz M. A.
- Micheli L.
- Miller J. K.
- Milosevic Djordjevic J.
- Mioni G.
- Miranda J. F.
- Misiak M.
- Modena A.
- Mokady A.
- Mola D.
- Moller Arlen
- Monajem A.
- Monteiro Renan P.
- Moon K.
- Morales Izquierdo Sara
- Morbée Sofie
- Moreau D.
- Morris K.
- Mosannenzadeh F.
- Moshontz H.
- Moss J. D.
- Muchembled F.
- Muda R.
- Muminov A.
- Mussaffa Butt M.
- Musser E.
- Nadif K.
- Ndukaihe I. L. G.
- Nedelcheva-Datsova Mina
- Neubauer A. B.
- Nguyen Thuy-vy
- Nicolotti M.
- Niemiec C. P.
- Nilsonne G.
- Nock N. L.
- Noone C.
- Norton J. O.
- Ntoumanis N.
- Ogbonnaya C. E.
- Olaya Torres A.
- Oliveira Raquel
- Olofsson J. K.
- Onie Sandersan
- Oosterlinck M.
- Ordoñez-Riaño Santiago
- Ortiz M. V.
- Ortiz M.S.
- Ostermann Thomas
- Ouherrou N.
- Overkott C.
- Paltrow Tamar
- Panagiotis R.
- Pantazi M.
- Papachristopoulos Konstantinos
- Papadatou-Pastou M.
- Parashar Neha
- Paris Bastien
- Paruzel-Czachura M.
- Parzuchowski M.
- Pavlacic J. M.
- Perillo Jennifer T.
- Pfuhl G.
- Picciocchi C.
- Pickering J. S.
- Pilato A.
- Pinto I.
- Pit I. L.
- Popović D.
- Pourafshari Razieh
- Primbs M. A.
- Pronizius E.
- Prusova I.
- Pöntinen Sara
- Quested E.
- Rachev N. R.
- Radtke Theda
- Rahal Rima-Maria
- Rahman Tasnim
- Rana K.
- Reeck C.
- Reggev Niv
- Reips Ulf-Dietrich
- Ren Dongning
- Reyna C.
- Ribeiro M. F. F.
- Ribeiro Rafael R.
- Richard Karley L.
- Roczniewska M.
- Rojas-Berscia L. M.
- Romanova M.
- Ropovik I.
- Ross Robert M.
- Rothbaum A. O.
- Roxas J. C. T.
- Ruiz-Fernández Susana
- Ryan Richard M.
- Ryan William S.
- Röer J. P.
- Sabristov M.
- Sacakli Asli
- Samojilenko L.
- Sanabria Pineda L. M.
- Sarieva I.
- Sarioguz Eylul
- Say N.
- Schei Vidar
- Schmidt K.
- Schmidt N-D.
- Schrötter J.
- Schulenberg Stefan E.
- Searston Rachel
- Seehuus M.
- Serrato Alvarez D.
- Sharifian M. H.
- Shi J.
- Silan M. A.
- Silva J. R.
- Simonovic N.
- Singer G.
- Singh Solorzano C.
- Singh A.
- Sinkolova Sladjana
- Sirota M.
- Skowronek A.
- Smit E. S.
- Soenens B.
- Song Xin
- Sorokowska Agnieszka
- Sorokowski Piotr
- Soto J. A.
- Sousa D.
- Standage M.
- Staniaszek K.
- Stephen I. D.
- Stieger Stefan
- Stojanovska Dragana
- Stojanovska M.
- Storage D.
- Stoyanova A.
- Studzinska Anna
- Suchow J. W.
- Sula I.
- Sunami N.
- Suter Lilian
- Sutherland C. A. M.
- Sverdrup Therese E.
- Szabelska A.
- Szala A.
- Szaszi Barnabas
- Szwed Paulina
- Taber J.
- Tajchman Zuzanna
- Tamnes C. K.
- Tatachari Srinivasan
- Tejada Rivera M. C.
- Terskova M.
- Theodoropoulou A.
- Thibault Landry A.
- Thogersen-Ntoumani C.
- Thomas A. G.
- Todsen A. L.
- Topor M.
- Toro M.
- Torunsky N.
- Tran Ulrich S.
- Travaglino G. A.
- Tshonda Sarah Suzette
- Tullett A. M.
- Tümer M.
- Unanue Wenceslao
- Urban J.
- Urooj A.
- Urriago-Rayo J.
- Urry H. L.
- Uttley J.
- Vaidis D. C.
- Valentova J. V.
- Vally Zahir
- van Antwerpen N.
- Van Doren N.
- van Hooff M. L. M.
- van Schie K.
- van Steenkiste I. M. M.
- Varella M. A. C.
- Vargas-Nieto J.C.
- Vasilev Martin R.
- Vaughn L. A.
- Vdovic M.
- Vega D.
- Verbruggen F.
- Verharen J. P. H.
- Vermote B. J.
- Vezirian K.
- Vieira L.
- Vilar Roosevelt
- Vilares I.
- Vilsmeier J. K.
- Vintr J.
- Volz L.
- Von Bastian Claudia C.
- von Bormann Suparpit M.
- Voracek M.
- Vranka Marek
- Vračar Selena
- Wachowicz J.
- Wajanatinapart Piyaorn
- Walczak Radoslaw B.
- Wang C.
- Warmelink L.
- Waterschoot J.
- Weinstein Netta
- Westerlund M.
- Westgate Erin C.
- Whitt C. M.
- Wichman A. L.
- Wielgus M.
- Willis M.
- Wilson John Paul
- Wolfe K.
- Wylie K.
- Xiao Qinyu
- Yamada Yuki
- Yeung Siu Kit
- Yu K.
- Zakharov I.
- Zambrano Ricaurte D.
- Zdybek Przemysław
- Ziano Ignazio
- Zickfeld J.
- Zorjan Saša
- Zrimsek Miha
- Zsido Andras N.
- Álvarez Solas Sara
- Çoksan Sami
- Özdoğru A. A.
- Čadek M.
- Šakan D.
- Štrukelj E.
- Žuro B.
- Publication venue
- 'Proceedings of the National Academy of Sciences'
- Publication date
- 27/05/2022
- Field of study
Finding communication strategies that effectively motivate social distancing continues to be a global public health priority during the COVID-19 pandemic. This cross-country, preregistered experiment (n = 25,718 from 89 countries) tested hypotheses concerning generalizable positive and negative outcomes of social distancing messages that promoted personal agency and reflective choices (i.e., an autonomy-supportive message) or were restrictive and shaming (i.e. a controlling message) compared to no message at all. Results partially supported experimental hypotheses in that the controlling message increased controlled motivation (a poorly-internalized form of motivation relying on shame, guilt, and fear of social consequences) relative to no message. On the other hand, the autonomy-supportive message lowered feelings of defiance compared to the controlling message, but the controlling message did not differ from receiving no message at all. Unexpectedly, messages did not influence autonomous motivation (a highly-internalized form of motivation relying on one’s core values) or behavioral intentions. Results supported hypothesized associations between people’s existing autonomous and controlled motivations and self-reported behavioral intentions to engage in social distancing: Controlled motivation was associated with more defiance and less long-term behavioral intentions to engage in social distancing, whereas autonomous motivation was associated with less defiance and more short- and long-term intentions to social distance. Overall, this work highlights the potential harm of using shaming and pressuring language in public health communication, with implications for the current and future global health challenges
Data-Driven Methodology for Prioritizing Traffic Signal Retiming Operations
- Author
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
Genome Sequencing and Analysis of the Biomass-Degrading Fungus \u3ci\u3eTrichoderma reesei\u3c/i\u3e (syn. \u3ci\u3eHypocrea jecorina\u3c/i\u3e)
- Author
- Arvas Mikko
- Baker Scott E.
- Barabote Ravi
- Berka Randy M.
- Brettin Thomas
- Bruce David
- Chapman Jarod
- Chertkov Olga
- Coutinho Pedro M.
- Cullen Dan
- Danchin Etienne G. J.
- de Leon Alfredo Lopez
- Detter Chris
- Dunn-Coleman Nigel
- Grigoriev Igor V.
- Han Cliff S.
- Harris Paul
- Henrissat Bernard
- Ho Isaac
- Jackson Melissa
- Kubicek Christian P.
- Kuske Cheryl R.
- Larrondo Luis F.
- Lucas Susan M.
- Magnuson Jon K.
- Martinez Diego
- Merino Sandy
- Misra Monica
- Nelson Beth
- Nelson Mary Anne
- Putnam Nicholas
- Richardson Paul
- Robbertse Barbara
- Rokhsar Daniel S.
- Rubin Edward M.
- Salamov Asaf A.
- Saloheimo Markku
- Schmoll Monika
- Schoch Conrad L.
- Terry Astrid
- Thayer Nina
- Ward Michael
- Westerholm-Parvinen Ann
- Xie Gary
- Yao Jian
- Publication venue
- DigitalCommons@University of Nebraska - Lincoln
- Publication date
- 01/05/2008
- Field of study
Trichoderma reesei is the main industrial source of cellulases and hemicellulases used to depolymerize biomass to simple sugars that are converted to chemical intermediates and biofuels, such as ethanol. We assembled 89 scaffolds (sets of ordered and oriented contigs) to generate 34 Mbp of nearly contiguous T. reesei genome sequence comprising 9,129 predicted gene models. Unexpectedly, considering the industrial utility and effectiveness of the carbohydrate-active enzymes of T. reesei, its genome encodes fewer cellulases and hemicellulases than any other sequenced fungus able to hydrolyze plant cell wall polysaccharides. Many T. reesei genes encoding carbohydrate-active enzymes are distributed nonrandomly in clusters that lie between regions of synteny with other Sordariomycetes. Numerous genes encoding biosynthetic pathways for secondary metabolites may promote survival of T. reesei in its competitive soil habitat, but genome analysis provided little mechanistic insight into its extraordinary capacity for protein secretion. Our analysis, coupled with the genome sequence data, provides a roadmap for constructing enhanced T. reesei strains for industrial applications such as biofuel production
Glucose-induced Autophagy of Peroxisomes in Pichia pastoris
- Author
- Ahlberg L.
- Baba M.
- Baba M.
- Bursch W.
- Chiang H.L.
- Dunn W.A.
- Dunn W.A.
- Dunn W.A.
- Egner R.
- Haas A.L.
- Hammond E.M.
- Harding T.M.
- Harding T.M.
- Hicke L.
- Hochstrasser M.
- Huang P.-H.
- Jonnalagadda S.
- Kato N.
- Koonin E.V.
- Kopitz J.
- Lammer D.
- Lang T.
- Lardeux B.R.
- Liakopoulos D.
- Mahajan R.
- Matunis M.J.
- Matunis M.J.
- Mizushima N.
- Mortimore G.E.
- Mortimore G.E.
- Per Eivind Strømhaug
- Randy W. Schekman
- Sandvig K.
- Schwarz S.E.
- Scott S.V.
- Scott S.V.
- Takeshige K.
- Thumm M.
- Titorenko V.I.
- Tsukada M.
- Tuttle D.L.
- Tuttle D.L.
- Veenhuis M.
- Weiping Yuan
- William A. Dunn
- Yuan W.
- Publication venue
- 'American Society for Cell Biology (ASCB)'
- Publication date
- Field of study