159 research outputs found
The Impact of Changing Project Organization Structure on Project Performance
Instigating changes to project organization structure during the project execution could disrupt many project processes and influence project performance. The purpose of this study is to investigate a particular problem occurred in completed construction projects in UAE market. The problem appeared due to unnecessary changes and slow or inadequate response to change by senior managers in contractor's project organization structure. These changes had negative impact on the project management roles and responsibilities, additional cost and time impact. Furthermore, there were negative consequences on the performance of the project's team and their effort to create new ideas as well as their innovation inside the construction project that they are involved. The qualitative methodology is used in this study through investigating five case studies for construction projects that completed in UAE market along with extensive literature review that focused on the different sides of the problem as well as an interview with ten members of contractor's project management and senior managers to examine the impact of the problem on project performance and team effectiveness. The main findings indicate that having clear and defined roles and responsibilities have positive impact on project performance and team effectiveness. Moreover, the contractor's senior managers have a vital role in establishing, managing the project organization structure and ensuring that any changes to the structure are dealt with effectively. This would enable the project to progress according to plan, reduce project activity reworks and address any weaking communication and cohesiveness between project team members
Optical Variability, Rotation Period and Inclination Angle of the M9.5 dwarf BRI 0021-0214
We report -band photometric observations of the radio-detected M9.5 dwarf
BRI 0021-0214, obtained with the Galway Ultra Fast Imager (GUFI) on the 1.8m
Vatican Advanced Technology Telescope VATT at Mt. Graham International
Observatory, Arizona. In total, 19 hours of observations over a 73 day baseline
were obtained. BRI 0021-0214 was shown to exhibit modulated emission with a
period of hours with a mean amplitude variability of 0.0044
mag. When combined with rotational velocity data obtained from previous work,
our newly discovered rotation period gives an inclination angle of
51.7 degrees for the rotation axis of BRI 0021-0214 relative to
our line of sight. Previous studies have reported that the most plausible cause
for optical variability from this dwarf is a consequence of suspended
co-rotating dust clouds in its atmosphere. However reports of enhanced
H and intermittent coherent radio emission suggest the possibility
of auroral activity in its magnetosphere. Further, more coordinated
multiwavlength observations of this dwarf could fully resolve the nature of
this elusive rapid-rotator object's observational properties
Holistic Review of Construction Process Carbon-Reduction Measures: A Systematic Literature Review Approach
The fragmented nature of construction operations makes it challenging to implement carbon-reduction strategies. However, attaining a holistic construction sector decarbonisation hinges upon ensuring all aspects of a construction project’s lifecycle are decarbonised, including the construction process stage. Therefore, to mitigate the implementation challenge of reducing the levels of carbon involved in construction processes, this study attempts to synthesise and categorise carbon-reduction strategies that could be employed to decrease the carbon footprint during a construction projects’ delivery. To achieve the aim of this study, a systematic literature review approach was adopted. Based on this technique, a total of 26 relevant articles within the built environment research area were eligible for the study, and their analysis revealed 56 carbon minimisation measures, which were summarised into nine distinct categories to ease their application and overcome the construction operations’ complexities. The nine categories include material transport, waste transport, materials and equipment, waste, materials, on-site office, on-site lighting, on-site transportation of material and equipment, and construction methods. The findings of this study provide contractors with a suite of measures that can be deployed to reduce the carbon impact of construction project delivery
The brown seaweeds of Scotland, their importance and applications
More than 50% of the UK coastline is situated in Scotland under legislative jurisdiction; therefore, there is a great opportunity for regionally focused economic development by the rational use of sustainable marine bio-sources. We review the importance of seaweeds in general, and more specifically, wrack brown seaweeds which are washed from the sea and accumulated in the wrack zone and their economic impact. Rules and regulations governing the harvesting of seaweed, potential sites for harvesting, along with the status of industrial application are discussed. We describe extraction and separation methods of natural products from these seaweeds along with their phytochemical profiles. Many potential applications for these derivatives exist in agriculture, energy, nutrition, biomaterials, waste treatment (composting), pharmaceuticals, cosmetics and other applications. The chemical diversity of the natural compounds present in these seaweeds is an opportunity to further investigate a range of chemical scaffolds, evaluate their biological activities, and develop them for better pharmaceutical or biotechnological applications. The key message is the significant opportunity for the development of high value products from a seaweed processing industry in Scotland, based on a sustainable resource, and locally regulated
The Role of Contractors in Reducing Carbon during Construction – A Preliminary Study
Construction contractors have been touted to be a major player in reducing carbon emissions during the construction process due to their role in bringing building designs to life. Also, various carbon reduction strategies have been highlighted in assisting contractors in reducing the carbon emitted while carrying out construction activities. However, it is believed that contractors are quite reluctant to adopt these strategies for several reasons, such as a possible increase in cost and being contradictory to their existing construction procedures. This paper, therefore, aims to highlight the report of a preliminary study done through the adoption of a systematised review approach in synthesising literature to understand what the evidence is as regards how contractors contribute towards the reduction of carbon during building construction activities. The findings reveal that there is a paucity of research in this research area as only 12 papers were found relating to the focus of this study. The analysis of these papers revealed eight possible ways (e.g. adoption of lean management principles, adoption of eco-hauling concept, and utilisation of modern digital tools) in which contractors contribute to carbon reduction during building construction projects. The findings of this study will benefit contractors looking for a suite of measures to implement in reducing their building construction project carbon footprint while also serving as a piece of foundational knowledge in the research area of carbon reduction during building construction projects. Lastly, a future study area worth exploring is proposed
A Systematic Review of the Business Contingencies Influencing Broader Adoption: Modern Methods of Construction (MMC)
The existing body of knowledge on the Modern Methods of Construction (MMC) reflects their benefits and relative advantages, particularly in addressing contemporary construction challenges. However, the uptake of such methods is minimal, particularly in the public construction sector. The low uptake has led MMC firms to liquidation due to the lack of an economy of scale. Studies, particularly recently, explain that the low adoption rates are linked to the inappropriateness of existing business models responsible for driving broader demand. This paper assumes that the lag in MMC adoption could be related to the ability of supply business models to communicate confidence to demand. Public clients are foreseen as important target customers, acquiring influential status across the industry, with an expected potential to drive innovation adoption across the sector. A systematic review method allows scholars to assess existing literature by critically locating and analysing relative publications to approach the study’s aim. Through utilising this method, the study classifies the arguments against the Business Model Canvas (BMC), and argues the results with respect to contingency theory, and in turn, synthesizing a new meaning that reveals the considerations needed to boost business model performance when penetrating the public sector. Hence, the critical analyses of 70 studies relative to MMC, led to proposing the contingencies that are believed to better structure business models. Results suggest that MMC firms can embrace specific reforms and gain more momentum when communicating confidence to public client organisations; however, a guideline that conceptualises the interactions between the elements and their influence on the decision-making does not exist, and this may be inhibiting coherency on how MMC businesses drive broader demand. To the authors’ knowledge, this is the first study to utilise the contingency theory as an attempt to disseminate previous efforts to explain the low adoption of MMC in the UK public sector
Examining the Influence of UK Public Clients’ Characteristics on Their Own Innovation-Decision towards the Modern Methods of Construction (MMC)
Construction has long been identified as an industry resistant to change and innovation, a reality that has prevailed to shape its overall reputation. The public sector includes an influential client type that dominates the major percentage of construction demand and is subject to public law. The Modern Methods of Construction (MMC) have been championed recently by the UK government and early adopters upon the emergence of data indicating their effectiveness in addressing key construction challenges. However, the uptake of MMC has been low among UK construction clients, particularly among public client organisations. Theories emerge across decades to inform researchers of variable clusters that can aid a broader understanding of decision-making and innovation adoption. One of the popular innovation theories suggests a relation between the characteristics of decision-makers and their own innovation decisions. This paper, therefore, aims to investigate the characteristics that are responsible for public clients’ low MMC uptake despite the associated relative advantages. Overall, 91 public client organisations have responded to this research’s survey, reflecting their organisation’s characteristics in line with the constructs adapted from the Diffusion of Innovation (DOI) theory. Results suggest that among the ten influences that are captured from a detailed review of the literature, confidence in MMC firms supersedes all other factors in critically influencing the organisation’s favourable decision towards using MMC. Evidence provided in this paper suggests that a communication issue is presenting itself in the public construction sector, which is evident by the lack of confidence that public clients have in MMC businesses. This is the first study to utilise quantitative means to examine construction clients’ characteristics and relate the same to the adoption of construction innovation. Future research is encouraged to acknowledge the most influencing characteristics and detail how such knowledge can be embraced by supply to develop business models that can orchestrate better confidence in the public sector
Radio Resource Management in NB-IoT Systems:Empowered by Interference Prediction and Flexible Duplexing
NB-IoT is a promising cellular technology for enabling low cost, low power, long-range connectivity to IoT devices. With the bandwidth requirement of 180 kHz, it provides the flexibility to deploy within the existing LTE band. However, this raises serious concerns about the performance of the technology due to severe interference from multi-tier 5G HetNets. Furthermore, as NB-IoT is based on HD-FDD, the symmetric allocation of spectrum band between the downlink and uplink results in underutilization of resources, particularly in the case of asymmetric traffic distribution. Therefore, an innovative RRM strategy needs to be devised to improve spectrum efficiency and device connectivity. This article presents the detailed design challenges that need to be addressed for the RRM of NB-IoT and proposes a novel framework to devise an efficient resource allocation scheme by exploiting cooperative interference prediction and flexible duplexing techniques
Contractors’ carbon reduction behaviour: UK construction professionals’ perspective
Purpose
The decisions of contractors could impact the reduction of construction carbon footprint. These decisions are linked to the belief of contractors which equally affects how they behave while delivering projects. This study aims to investigate the behavioural tendencies of contractors that could lead to carbon minimisation during the execution of construction projects.
Design/methodology/approach
An industry survey was performed amongst 41 UK construction professionals. Spearman’s correlation and factor analysis were used to analyse the data.
Findings
The result of the Spearman’s correlation gave rise to 14 contractors’ carbon reduction behaviour (CCRB) variables and their factor analysis yielded two distinct factors, namely, contractors’ consummate carbon reduction behaviour and contractors’ pragmatic carbon reduction behaviour. The findings suggest that in the UK, contractors are willing to take voluntary practical steps to decrease the carbon footprint of construction projects.
Practical implications
This finding might be unexpected to construction stakeholders, especially construction clients who may believe that infusing strict carbon reduction obligations in contracts is sufficient in nudging contractors to lessen the carbon impact of projects.
Originality/value
The study attempted to quantitatively derive CCRB, thereby extending the breadth of knowledge in the construction carbon reduction domain
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5-aza-2′-deoxycytidine induces telomere dysfunction in breast cancer cells
Supplementary material is available online at: https://www.sciencedirect.com/science/article/pii/S0753332224010576?via%3Dihub#sec0140 .Aims:
Azacitidine, a drug that epigenetically modifies DNA, is widely used to treat haematological malignancies. However, at low doses, it demethylates DNA, and as a result, can alter gene expression. In our previous publication, we showed that low doses of azacitidine induce telomere length elongation in breast cancer cells. In this study, we aim to identify the mechanisms which lead to telomere length increases.
Methods:
Breast cancer cell lines representing different molecular sub-types were exposed to 5-aza-2′-deoxycytidine (5-aza) in 2 and 3D cultures, followed by DNA, RNA, and protein extractions. Samples were then analysed for telomere length, DNA damage, telomerase, and ALT activity.
Results:
We show that treatment of the cell lines with 5-aza for 72 h induced DNA damage at the telomeres and increased ALT activity 3-fold. We also identified a gene, POLD3, which may be involved in the ALT activity seen after treatment.
Conclusion:
Our results indicate that while 5-aza is a useful drug for treating haematological cancers, surviving cancer cells that have been exposed to lower doses of the drug may activate mechanisms such as ALT. This could lead to cancer cell survival and possible resistance to 5-aza clinically.This work was partly funded by a BRIEF award (11683101) from Brunel University
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