Use of oral glucocorticoids and risk of skin cancer and non-Hodgkin's lymphoma: a population-based case–control study

In North Jutland County, Denmark, we investigated whether use of oral glucocorticoids was associated with an increased risk of developing basal cell carcinoma (BCC), squamous cell carcinoma (SCC), malignant melanoma (MM), and non-Hodgkin's lymphoma (NHL). From the Danish Cancer Registry we identified 5422 BCC, 935 SCC, 983 MM, and 481 NHL cases during 1989–2003. Using risk-set sampling we selected four age- and gender-matched population controls for each case from the Civil Registration System. Prescriptions for oral glucocorticoids before diagnosis were obtained from the Prescription Database of North Jutland County on the basis of National Health Service data. We used conditional logistic regression to estimate incidence rate ratios (IRRs), adjusting for chronic medical diseases (information about these were obtained from the National Patient Registry) and use of other immunosuppressants. We found slightly elevated risk estimates for BCC (IRR, 1.15 (95% CI: 1.07–1.25)), SCC (IRR, 1.14 (95% CI: 0.94–1.39)), MM (IRR, 1.15 (95% CI: 0.94–1.41), and NHL (IRR, 1.11 (95% CI: 0.85–1.46)) among users of oral glucocorticoids. Our study supports an overall association between glucocorticoid use and risk of BCC that cannot be explained by the presence of chronic diseases or concomitant use of other immunosuppressants

The Physiology Of Domestic Animals

21 cm; 1020 ha

Muzzle morphology and food consumption by pudu ( Pudu puda

The southern pudu (Pudu puda) is one of the smallest living deer of the world. It inhabits the temperate rainforest of Chile and Argentina, where it is considered vulnerable due to decreasing populations. To improve the existing information concerning its feeding ecology, we performed morphometric measurements on skulls and jaws (n = 22), and observed feeding behavior on individual deer (n = 14). The pudu presented an oral morphology adapted to select specific parts of plants, and a brachyodont molar type, which is consistent with the selective browsing style and consumption of primarily dicotyledonous plants. This information can be used to infer habitat relationships and needs of the pudu during the growth season.El pudú del sur (Pudu puda) en uno de los ciervos más pequeños del mundo y habita el bosque templado lluvioso de Chile y Argentina. Es considerado vulnerable debido a una continua reducción de sus poblaciones. Con el fin de añadir información concerniente a su ecología y uso de hábitat, se realizaron mediciones morfométricas en cráneos y mandíbulas (n=22), además de observaciones del comportamiento de alimentación en individuos de esta especie (n=14). El pudú presentó una morfología bucal adaptada para seleccionar partes específicas de la vegetación que consumen y molares braquiodontos, siendo coherente con el estilo de ramoneador selectivo y el consumo, principalmente, de dicotiledóneas.</p