La formation des professeurs d'éducation physique sportive par la recherche : vers l'élaboration des savoirs professionnels

This training aims at making the trainee capable of analysing his PE teaching methods from a didactic viewpoint through a research activity. The writing of the teacher training report affards an opportunity of training alternating with research. Each trainee has to carry out an experiment starting from the identification of a research hypothesis connected with a professional problem. Evaluation reveals that an initiation into research can bring solutions to concrete teaching problems through controlled praxeological knowledge. It requires a theorization of this type of training.L 'objet de la formation est de permettre au professeur-stagiaire d'analyser ses pratiques d'enseignement de l'EPS du point de vue didactique, à partir d'une activité de recherche. La production du rapport de Centre Pédagogique Régional (CPR) constitue le prétexte d'une mise en situation de formation alternée par la recherche. Chaque professeur-stagiaire s'engage à mettre en œuvre une expérimentation à partir de l'identification d'une hypothèse de recherche liée à un problème professionnel. L'évaluation met en évidence qu'une initiation à la recherche peut apporter des solutions aux problèmes concrets d'enseignement par la production de connaissances praxéologiques contrôlées. Elle rend nécessaire une théorisation de ce type de formation.Amade-Escot Chantal, Barrue J.-P., Dugrand M., Terrisse André. La formation des professeurs d'éducation physique sportive par la recherche : vers l'élaboration des savoirs professionnels. In: Recherche & Formation, N°7, 1990. Les professions de l'éducation : recherches et pratiques en formation. pp. 85-101

Intravenous NPA for the treatment of infarcting myocardium early: InTIME-II, a double-blind comparison on of single-bolus lanoteplase vs accelerated alteplase for the treatment of patients with acute myocardial infarction

Aims to compare the efficacy and safety of lanoteplase, a single-bolus thrombolytic drug derived from alteplase tissue plasminogen activator, with the established accelerated alteplase regimen in patients presenting within 6 h of onset of ST elevation acute myocardial infarction. Methods and Results 15 078 patients were recruited from 855 hospitals worldwide and randomized in a 2:1 ratio to receive either lanoteplase 120 KU. kg-1 as a single intravenous bolus, or up to 100 mg accelerated alteplase given over 90 min. The primary end-point was all-cause mortality at 30 days and the hypothesis was that the two treatments would be equivalent. By 30 days, 6.61% of alteplase-treated patients and 6.75% lanoteplase-treated patients had died (relative risk 1.02). Total stroke occurred in 1.53% alteplase- and 1.87% lanoteplase-treated patients (ns); haemorrhagic stroke rates were 0.64% alteplase and 1.12% lanoteplase (P=0.004). The net clinical deficit of 30-day death or non-fatal disabling stroke was 7.0% and 7.2%, respectively. By 6 months, 8.8% of alteplase-treated patients and 8.7% of lanoteplase-treated patients had died. Conclusion Single-bolus weight-adjusted lanoteplase is an effective thrombolytic agent, equivalent to alteplase in terms of its impact on survival and with a comparable risk-benefit profile. The single-bolus regimen should shorten symptoms to treatment times and be especially convenient for emergency department or out-of-hospital administration. (C) 2000 The European Society of Cardiology