Assess the Effectiveness of Magnesium Sulphate Dressing Versus Cold Compress in Patients with Intravenous Infiltrations

A study was conducted to compare the effectiveness of magnesium sulphate dressing versus cold compress in patients with intravenous infiltrations. The research method adopted for the study was quasi-experimental approach. Samples were divided in two groups, each consisting 30. Purposive sampling technique was used to select the sample for the study. The difference in reduction in intravenous infiltration of both groups is statistically significant; investigator feels that the magnesium sulphate dressing is better than cold compress for reducing intravenous infiltration

Margaret Atwood: Voicing transition in the Conscience of Women

Margaret Atwood, a prominent Canadian novelist, in her novels has proficiently and subtly voiced transition in the conscience of contemporary women. Through her vivid female characters and poignant themes, she has explored various shades and aspects of – not only mind but also of body— of a woman. The inside turmoil, thoughts, frustrations and anxieties, have been adeptly dealt in narratives of the novels, and have been depicted through various external disorders that occurs at mental and physical levels caused by inner dissatisfactions. Through the journey of her female characters she not only, assertively, presents the internal as well as outer condition of women, but also proposes solution to end the overshadowed state of existence of women by men and society. Atwood impressively delineates in her stories – the changed ‘conscience’ of women— that also support and propagate the concept of “New Woman”. The paper aims at locating the points where the breakthrough in the stereotyped feminine conscience occurs, paving way for the origin of new women in the selected novels of Atwood

Assess the Effects of Planned Teaching Programme on Knowledge regarding Glasgow Coma Scale among Staff Nurses Working in Selected Hospital at Bhopal

The present study was conducted to assess the effect of Planned teaching Programme on knowledge regarding Glass coma Scale among staff nurses working in selected hospital at Bhopal. An experimental design was chosen with pre-test and post-test of experimental and control group. The sample size was 60 Staff Nurses divided into two groups as 30 in experimental and 30 in control group. The tools used for conducting the study included demographic data, self structured questionnaire to assess knowledge of experimental and control group. The experimental group was given Planned teaching Programme as an intervention and the control group was used for comparison only without interventions. The data were analyzed with statistics and unpaired t-test was done. The study clearly shows that there was a significant gain in knowledge of Staff Nurses in experimental group with PTP which emphasizes that Teaching Staff Nurses on Glass Coma Scale improves Nursing Care of Unconscious patients. Therefore the Staff Nurses can be benefited with PTP to improve knowledge and practice on Unconscious patients

Clinico-Pathological Review on Pravahika vis-a-vis Amoebiasis

The disease Pravahika (Amoebiasis) is described after the description of Atisara (Diarrhea). Critical study of the etiopathogenesis and clinical features of Pravahika in relation to the disease amoebic dysentery as described in modern medicine reveal that the disease Pravahika includes the varied clinical syndromes of amoebic dysentery. Pravahika is a disorder of variable clinical picture. Amoebic dysentery is also of wider range with gradual onset. Pravahika may include some other dysentery also. It may not be possible to identify E. histolytica in all cases of pravahika. Similarly all cases of amoebic dysentery may not have tenesmus or Pravahana. It can be said that Pravahika is the only condition described in Ayurveda which can include amoebiasis i.e. amoebic dysentery

APOPTOSIS INDUCING EFFECT OF SILVER NANOPARTICLES SYNTHESIZED USING MAGNOLIA CHAMPACA LEAF EXTRACT ON MCF-7 CELL LINE

Objective: To synthesize silver nanoparticle (AgNP) using the ethanolic leaf extract of Magnolia champaca (MC-AgNP) and to evaluate its cytotoxicity and apoptotic activity in MCF-7 cell line, and to analyse active Caspase-3 expression in inducing apoptosis. Methods: AgNP was green synthesized using ethanolic leaf extract of MC. Shape and size were analysed by SEM and particle size analyser. Cytotoxicity was tested to find IC50 value. Apoptosis was explored by mitochondrial membrane potential (ΔΨm) assay and active Caspase-3 expression study using flow cytometry. Results: AgNP synthesized was observed to be in spherical shape through SEM micrograph with 164.6 nm in size. IC50 value of 15.90 µg/ml was obtained after 24 h of drug treatment. Changes in ΔΨm and positive active Caspase-3 protein expression were observed. Conclusion: The present results suggest that MC-AgNP has potential anticancer property and also induced cell death via apoptosis through caspase dependent pathway in MCF-7 cells

Screening of in vitro Antimicrobial Potential of Fermentation Extracts Prepared from Indigenous Lactobacillus Isolates

Recently, efforts are being made to efficiently employ the probiotic bacteria in non-dairy products either as supplemental additive or for fermentation which might have several advantages over the probiotic dairy products such avoiding milk protein allergies, lactose intolerance or hyper cholesterolemia. So the present study aimed at screening of certain indigenous lactobacillus species responsible with antimicrobial potential against common pathogenic microorganism when allowed to ferment in liquid culture medium. The indigenous Lactobacillus spp. were isolated using different dairy samples like milk, curd, butter milk, cheese etc., on selective MRS agar medium and pure cultures were partially identified referring Bergey’s Manual of Systematic Bacteriology based on morphological, cultural and biochemical reactions. The selected pure cultures were allowed to ferment in MRS broth for 7 days at 37oC in with intermittent shaking of culture flasks. There were total 14 isolates of Lactobacillus spp. were obtained. According to the results of biochemical tests as described in table 1 the probability of LAB would have been L.acidophilus, L.fermentum, L.plantarum, L.casei, L. ruteri or L.rhamnosus. Out of the 14 indigenously isolated Lactobacillus spp., the cell free fermentation extract of the isolates LB-2, LB-3, LB-5, LB-6, LB-7, LB-9, LB-11, LB-12, LB-13 and LB-14 was found imparted antimicrobial activity over the test microbial species including Escherichia coli (MTCC-1687), Pseudomonas aeroginosa (MTCC-*1934), Staphylococcus aureus (MTCC-737) and Candida albicans (MTCC-227), due to unknown substances secreted within fermentation extract. The ability to produce antagonistic substances during the process of fermentation could be explored extensively for identification, purification and use in food preservation at both domestic as well as industrial levels. Keywords: Therapeutics, Antimicrobial activity, Lactobacillus, Fermentation extract

An earth-friendly herbal pesticide from Pongamia pinnata L.

Today use of hazardous chemical pesticides is a major environmental problem in global agriculture. The large scale use of these pesticides is degrading soil quality, underground and surface water quality, food quality of products. Herbal pesticides are a potential option for their chemical counterparts. It was observed that the crop fields where Pongamia pinnata trees are planted, there is less or no infestation of various insect-pests round the year.The trees of Pongamia pinnata are found allover India and the use of Pongamia as pesticide is cost effective, environment friendly and is in the reach of common villagers and farmers of India

Clinico-etiological pattern of lower gastrointestinal bleeding in children (5-18 years age group) at a tertiary care center in central India

Background: Lower gastrointestinal bleeding (LGIB), defined as bleeding occurring distal to the ligament of Treitz, is a common presenting symptom in pediatric patients. Objective: To understand the clinico-etiological pattern of LGIB in children in the age group 5-18 years. Materials and Methods: This prospective study was carried out at a tertiary health-care center in central India between January 2011 and August 2012. We consecutively enrolled all patients in the age group 5-18 years who came to our center with gross LGIB or two consecutive positive occult blood tests with at least 1-week interval between tests. All patients underwent colonoscopy (small, flexible Olympus PCF-20 colonoscope) and the findings were recorded. The procedure was done only after proper informed consent from the parents. Results: Total 38 patients were included in the study with above-mentioned inclusion and exclusion criteria, during the study period. Male to female ratio in LGIB was 2.16:1. LGIB was most common in children aged 5-10 years (63.1%), followed by 10-14 years (26.3%). Hematochezia was the most common presenting symptom (78.9%) followed by melena (21.1%). The most common causes of LGIB were colitis and colorectal polyp (31.6% each) followed by anal fissures (21.1%). Anemia was present in 68.4% patients at the time of presentation. Recurrence of LGIB was noted in 18 (47.4%) patients. Conclusion: We conclude that LGIB is most common in 5-10 years of children (school age) with hematochezia as the most common presenting symptom. Causes of LGIB in children in developing countries are same as developed countries (polyps and colitis being most common, followed by anal fissure), but further studies are required to determine the significant correlation between findings

Fin based active control for ship roll motion stabilization

Ship roll motion control is important for vessels engaged in oceanographic research activities and this paper focuses on the design of a controller for fin based roll motion stabilization of a Coastal Research Vessel (CRV). Based on the geometry of a pair of actuator fins installed at the midship of the vessel, the hydrodynamic coefficients are calculated for the vessel including the fin lift capacity. The wave disturbances are simulated as a sine time series. The objective is to design a Linear Quadratic Regulator (LQR), a state feedback controller and obtain the performance of the system. The larger objective is to implement the system eventually in laboratory scale physical simulations in wave environment. This paper primarily presents the design of the control system and evaluation through Simulink in Matlab environment. The global cost function of the system is minimized by precision tuning of the two control parameters (or weighting matrices), Q and R. The system analysis is done using frequency domain and state space approach. The simulation results show that the natural frequency and roll response closely match with the response of the physical model (CRV) in laboratory environment, as observed during the experimental study. The proposed control system is compared with a conventional PID controller. The simulation results demonstrate the effectiveness of the designed roll motion stabilization system with significant roll reduction over the operational range of the vessel

A Study to Assess the Effectiveness of Abdominal Breathing Exercise in Reduction of Blood Pressure Among Hypertensive Patients in Selected Hospitals at Bhopal

Background: Abdominal breathing exercise is one among these. It reduces blood pressure by increasing baroreflex sensitivity and reducing sympathetic activity and chemo reflex activation. In India, it is reported that there are around 42% people are with pre hypertension, 15% are newly diagnose to have Hypertension and 31% are with known case of hypertension, and it kills nearly 8 million people every year worldwide. The noncompliance with treatment, stress and life style are found to be major reason for this doubling of disease within a decade, there “arises need for new therapies ‘and’ remedies. Objectives: The study aimed to assess the effectiveness of abdominal breathing exercise in reducing mean blood pressure among hypertensive patients. Methods: Pre-experimental one group pre-test – post-test design was adopted for the study. 60 hypertensive patients from male and female medical general ward had been selected by convenient sampling. Tool comprised of Demographic proforma contained 9 items and sphygmomanometer, stethoscope and blood pressure monitoring table contained 3 items to record the readings. The reliability of the tool was tested by inter-rater method and it was found to be r = 0.99. Abdominal breathing exercise was administered to the samples after pre-assessment of mean blood pressure for ten minutes and post assessment of mean blood pressure is done at the gap of 5 minutes which is repeated 3 times a day and monitored for minimum of 3 days. ‘t’ test was used for finding the effectiveness, and Chi square test was used for finding out the association between mean blood pressure and selected demographic variables. Results: It revealed that the mean differences in pre and post assessment was5.61 and ‘t’ value was 19.39 which is more than the ‘t’ table value. The overall findings of the study revealed that the Conclusion: the study concluded that abdominal breathing exercise is found to be very effective in reducing the mean blood pressure