Convolutional Neural Network–Based Automatic Classification of Colorectal and Prostate Tumor Biopsies Using Multispectral Imagery: System Development Study

Background: Colorectal and prostate cancers are the most common types of cancer in men worldwide. To diagnose colorectal and prostate cancer, a pathologist performs a histological analysis on needle biopsy samples. This manual process is time-consuming and error-prone, resulting in high intra- and interobserver variability, which affects diagnosis reliability. Objective: This study aims to develop an automatic computerized system for diagnosing colorectal and prostate tumors by using images of biopsy samples to reduce time and diagnosis error rates associated with human analysis. Methods: In this study, we proposed a convolutional neural network (CNN) model for classifying colorectal and prostate tumors from multispectral images of biopsy samples. The key idea was to remove the last block of the convolutional layers and halve the number of filters per layer. Results: Our results showed excellent performance, with an average test accuracy of 99.8% and 99.5% for the prostate and colorectal data sets, respectively. The system showed excellent performance when compared with pretrained CNNs and other classification methods, as it avoids the preprocessing phase while using a single CNN model for the whole classification task. Overall, the proposed CNN architecture was globally the best-performing system for classifying colorectal and prostate tumor images. Conclusions: The proposed CNN architecture was detailed and compared with previously trained network models used as feature extractors. These CNNs were also compared with other classification techniques. As opposed to pretrained CNNs and other classification approaches, the proposed CNN yielded excellent results. The computational complexity of the CNNs was also investigated, and it was shown that the proposed CNN is better at classifying images than pretrained networks because it does not require preprocessing. Thus, the overall analysis was that the proposed CNN architecture was globally the best-performing system for classifying colorectal and prostate tumor images

Breast Cancer Detection in Thermography Using Convolutional Neural Networks (CNNs) with Deep Attention Mechanisms

Breast cancer is one of the most common types of cancer among women. Accurate diagnosis at an early stage can reduce the mortality associated with this disease. Governments and health organizations stress the importance of early detection of breast cancer as it is related to an increase in the number of available treatment options and increased survival. Early detection gives patients the best chance of receiving effective treatment. Different types of images and imaging modalities are used in the detection and diagnosis of breast cancer. One of the imaging types is “infrared thermal” breast imaging, where a screening instrument is used to measure the temperature distribution of breast tissue. Although it has not been used often, compared to mammograms, it showed promising results when used for early detection. It also has many advantages as it is non-invasive, safe, painless, and inexpensive. The literature has indicated that the use of thermal images with deep neural networks improves the accuracy of early diagnosis of breast malformation. Therefore, in this paper, we aim to investigate to what extent convolutional neural networks (CNNs) with attention mechanisms (AMs) can provide satisfactory detection results in thermal breast cancer images. We present a model for breast cancer detection based on deep neural networks with AMs using thermal images from the Database for Research Mastology with Infrared Image (DMR-IR). The model will be evaluated in terms of accuracy, sensitivity and specificity, and will be compared against state-of-the-art breast cancer detection methods. The AMs with the CNN model achieved encouraging test accuracy rates of 99.46%, 99.37%, and 99.30% on the breast thermal dataset. The test accuracy of CNNs without AMs was 92.32%, whereas CNNs with AMs achieved an improvement in accuracy of 7%. Moreover, the proposed models outperformed previous models that were reviewed in the literature

Brain MRI Analysis for Alzheimer’s Disease Diagnosis Using CNN-Based Feature Extraction and Machine Learning

Alzheimer’s disease is the most common form of dementia and the fifth-leading cause of death among people over the age of 65. In addition, based on official records, cases of death from Alzheimer’s disease have increased significantly. Hence, early diagnosis of Alzheimer’s disease can increase patients’ survival rates. Machine learning methods on magnetic resonance imaging have been used in the diagnosis of Alzheimer’s disease to accelerate the diagnosis process and assist physicians. However, in conventional machine learning techniques, using handcrafted feature extraction methods on MRI images is complicated, requiring the involvement of an expert user. Therefore, implementing deep learning as an automatic feature extraction method could minimize the need for feature extraction and automate the process. In this study, we propose a pre-trained CNN deep learning model ResNet50 as an automatic feature extraction method for diagnosing Alzheimer’s disease using MRI images. Then, the performance of a CNN with conventional Softmax, SVM, and RF evaluated using different metric measures such as accuracy. The result showed that our model outperformed other state-of-the-art models by achieving the higher accuracy, with an accuracy range of 85.7% to 99% for models with MRI ADNI dataset

Brain MRI Analysis for Alzheimer’s Disease Diagnosis Using CNN-Based Feature Extraction and Machine Learning

Alzheimer’s disease is the most common form of dementia and the fifth-leading cause of death among people over the age of 65. In addition, based on official records, cases of death from Alzheimer’s disease have increased significantly. Hence, early diagnosis of Alzheimer’s disease can increase patients’ survival rates. Machine learning methods on magnetic resonance imaging have been used in the diagnosis of Alzheimer’s disease to accelerate the diagnosis process and assist physicians. However, in conventional machine learning techniques, using handcrafted feature extraction methods on MRI images is complicated, requiring the involvement of an expert user. Therefore, implementing deep learning as an automatic feature extraction method could minimize the need for feature extraction and automate the process. In this study, we propose a pre-trained CNN deep learning model ResNet50 as an automatic feature extraction method for diagnosing Alzheimer’s disease using MRI images. Then, the performance of a CNN with conventional Softmax, SVM, and RF evaluated using different metric measures such as accuracy. The result showed that our model outperformed other state-of-the-art models by achieving the higher accuracy, with an accuracy range of 85.7% to 99% for models with MRI ADNI dataset

A novel fast Otsu digital image segmentation method

Steganography is the art of hiding user information in various file types including image, audio and video. Security of steganography lies in imperceptibility of secret information in the cover image. Human Visual System (HVS) is not able to detect the changes in low color values of an image. To the best of our knowledge, none of the available steganographic techniques have exploited this weakness of HVS. In this paper, a new LSB technique is presented which hides information in the cover image taking into account the pixel value of color or grey level of every pixel. Our experiments show that the proposed technique has a high payload and low perceptibility of secret information hidden in the cover image as compared to the existing Least Significant Bit (LSB) based algorithms. We have used MATLAB for the implementation of proposed algorithm

Novel fingerprint segmentation with entropy-Li MCET using log-normal distribution

Fingerprint recognition is an important biometric application. This process consists of several phases including fingerprint segmentation. This paper proposes a new method for fingerprint segmentation using a modified Iterative Minimum Cross Entropy Thresholding (MCET) method. The main idea is to model fingerprint images as a mixture of two Log-normal distributions. The proposed method was applied on bi-modal fingerprint images and promising experimental results were obtained. Evaluation of the resulting segmented fingerprint images shows that the proposed method yields better estimation of the optimal threshold than does the same MCET method with Gamma and Gaussian distributions

Early Detection of Seasonal Outbreaks from Twitter Data Using Machine Learning Approaches

Seasonal outbreaks have several different periods that occur primarily during winter in temperate regions, while influenza may occur throughout the year in tropical regions, triggering outbreaks more irregularly. Similarly, dengue occurs in the star of the rainy season in early May and reaches its peak in late June. Dengue and flu brought an impact on various countries in the years 2017–2019 and streaming Twitter data reveals the status of dengue and flu outbreaks in the most affected regions. This research work presents that Social Media Analysis (SMA) can be used as a detector of the epidemic outbreak and to understand the sentiment of social media users regarding various diseases. Providing awareness about seasonal outbreaks through SMA is an effective approach for researchers and healthcare responders to detect the early outbreaks. The proposed model aims to find the sentiment about the disease in tweets, and the seasonal outbreaks-related tweets are classified into two classes as disease positive and disease negative. This work proposes a machine-learning-based approach to detect dengue and flu outbreaks in social media platform Twitter, using four machine learning algorithms: Random Forest (RF), K-Nearest Neighbor (KNN), Support Vector Machine (SVM), and Decision Tree (DT), with the help of Term Frequency and Inverse Document Frequency (TF-IDF). For experimental analysis, two datasets (dengue and flu) are analyzed individually. The experimental results show that the RF classifier has outperformed the comparison models in terms of improved accuracy, precision, recall, F1-measure, and Receiver Operating Characteristic (ROC) curve. The proposed work offers favorable performance with total precision, accuracy, recall, and F1-measure ranging from 84% to 88% for conventional machine learning techniques

Arabic Fake News Detection: Comparative Study of Neural Networks and Transformer-Based Approaches

Fake news detection (FND) involves predicting the likelihood that a particular news article (news report, editorial, expose, etc.) is intentionally deceptive. Arabic FND started to receive more attention in the last decade, and many detection approaches demonstrated some ability to detect fake news on multiple datasets. However, most existing approaches do not consider recent advances in natural language processing, i.e., the use of neural networks and transformers. This paper presents a comprehensive comparative study of neural network and transformer-based language models used for Arabic FND. We examine the use of neural networks and transformer-based language models for Arabic FND and show their performance compared to each other. We also conduct an extensive analysis of the possible reasons for the difference in performance results obtained by different approaches. The results demonstrate that transformer-based models outperform the neural network-based solutions, which led to an increase in the F1 score from 0.83 (best neural network-based model, GRU) to 0.95 (best transformer-based model, QARiB), and it boosted the accuracy by 16% compared to the best in neural network-based solutions. Finally, we highlight the main gaps in Arabic FND research and suggest future research directions