Localization of Deep Abscesses with Radioactive Isotopes: An Experimental Study

Life-endangering effects of deep abscesses make early and precise identification and localization important to permit adequate surgical drainage. An experiment was undertaken to study the feasibility of detecting abscesses by using leucocytes tagged with radioactive isotopes. For the labeling, 51chromium appeared preferable to 131iodine or 99technetium. Leucocytes so labelled will concentrate sufficiently in abscesses to permit identification of abscesses by scintillation scanning. For clinical application, techniques require further simplification and refinement to eliminate interference by collection of radioactive isotopes in the liver and spleen

Isotope Cisternography — RISA®

Several cases are presented which illustrate the indications and results of a relatively new procedure of intrathecal injection of radioiodinated human seruin albumin I 131 to demonstrate cerebrospinal fluid dynamics. This procedure has been used in conjunction with pneumoencephalography in the diagnosis of communicating hydrocephalus. A proper dose as well as adequate volume are necessary to obtain diagnostic scans