6,926 research outputs found
Distributed Adaptive Greedy Quasi-Newton Methods with Explicit Non-asymptotic Convergence Bounds
Though quasi-Newton methods have been extensively studied in the literature,
they either suffer from local convergence or use a series of line searches for
global convergence which is not acceptable in the distributed setting. In this
work, we first propose a line search free greedy quasi-Newton (GQN) method with
adaptive steps and establish explicit non-asymptotic bounds for both the global
convergence rate and local superlinear rate. Our novel idea lies in the design
of multiple greedy quasi-Newton updates, which involves computing
Hessian-vector products, to control the Hessian approximation error, and a
simple mechanism to adjust stepsizes to ensure the objective function
improvement per iterate. Then, we extend it to the master-worker framework and
propose a distributed adaptive GQN method whose communication cost is
comparable with that of first-order methods, yet it retains the superb
convergence property of its centralized counterpart. Finally, we demonstrate
the advantages of our methods via numerical experiments
Feasibility and effect of para-right bundle branch pacing in patients with atrial fibrillation and complete atrioventricular block
Background: Chronic right ventricular apex (RVA) pacing can induce negative clinical effects. The aim of the present study was to compare RVA pacing with para-right bundle branch (para-RBB) pacing in terms of electrocardiogram (ECG) and echocardiographic (ECHO) features.
Methods: Forty-one consecutive persistent atrial fibrillation patients with an indication for permanent pacing treatment due to complete atrioventricular block were randomly assigned to receive a screw-in lead either in the RVA (n = 22) or at the para-RBB (n = 19). Para-RBB pacing leads were located according to the RBB potential recorded by electrophysiology catheter. ECG was recorded before and after implantation. All patients underwent the pacemaker programming at 1 day, 6 months, 12 months and 24 months after implantation. ECHO examination was performed during follow-up at 6, 12 and 24 months after implantation to assess the heart function and synchronism.
Results: There was no significant difference in pacing lead parameters between para-RBB pacing group and RVA pacing group. Compared with RVA pacing group, the para-RBB pacing group obtained a narrower QRS complex, more synchronic ventricular systole, and less negative effect on heart function (p < 0.05).
Conclusions: Para-RBB pacing has potential clinical benefits and may be a physiological pacing site.
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