72 research outputs found
Institutional Distance and Location Choice of Multinational Enterprises
Even though scholars have realized the importance of the impact of the institutional environment on the strategy of MNEs, most of them have overlooked the first and essential step of the FDI decision—location choice. In this paper, we link institutional theory and location choice literature and propose that the difference in the host country and home country‘s institutional environments - institutional distance - has a negative effect on the FDI‘s location choice. We also formulate hypotheses about firm specific attributes that may moderate this impact of institutional distance on location choice. Using data on Japanese companies‘ FDI information and the World Bank Governance indicator, we empirically test these ideas and the results show that the greater institutional distance significantly diminishes the MNE's intention to invest
New improvement to Falconer distance set problem in higher dimensions
We show that if a compact set has Hausdorff dimension
larger than , where , then
there is a point such that the pinned distance set has
positive Lebesgue measure. This improves upon bounds of Du-Zhang and
Du-Iosevich-Ou-Wang-Zhang in all dimensions . We also prove lower
bounds for Hausdorff dimension of pinned distance sets when , which improves upon bounds of Harris
and Wang-Zheng in dimensions .Comment: 36 page
Weighted refined decoupling estimates and application to Falconer distance set problem
We prove some weighted refined decoupling estimates. As an application, we
give an alternative proof of the following result on Falconer's distance set
problem by the authors in a companion work: if a compact set has Hausdorff dimension larger than
, where , then there is a
point such that the pinned distance set has positive
Lebesgue measure. Aside from this application, the weighted refined decoupling
estimates may be of independent interest.Comment: 28 pages. arXiv admin note: text overlap with arXiv:2309.0410
Patients\u27 Acceptance of Smartphone Health Technology for Chronic Disease Management: A Theoretical Model and Empirical Test
Les quatre textes ont en commun de présenter certaines évolutions récentes de l’histoire politique en Allemagne. Ils prennent tous position face à trois tournants historiographiques. La notion d’histoire culturelle du politique peut servir d’emblème au premier de ces tournants : le politique est envisagé non plus comme une succession d’événements ni comme le fruit de déterminations structurelles dont il serait la superstructure ou l’écume, mais comme l’expression de valeurs et de procédures o..
Physical function, ADL, and depressive symptoms in Chinese elderly: Evidence from the CHARLS
BackgroundDepressive symptoms are a serious public health problem that affects the mental health of older adults. However, current knowledge of the association between ADL disability and physical dysfunction and depressive symptoms in Chinese adults is insufficient. We intend to analyze the association between physical function, ADL, and depressive symptoms in older Chinese adults.MethodsThe data obtained from the China Health and Retirement Longitudinal Survey (2015 and 2018) (CHARLS). This includes 3,431 in 2015 and 3,258 in 2018 over the age of 60. Comparing 2015 and 2018 data, multivariate logistic regression models were used to explore the relationship between physical function, ADL, and depressive symptoms in urban and rural older adults, adjusting for sociodemographic factors associated with depression in older adults.ResultsThe prevalence of depressive symptoms among older adults in China was 33.8 percent in 2015 and 50.6 percent in 2018. In baseline data from 2015 and 2018, residence, gender, marital status, drinking, physical function, ADL, and self-rated health were all found to be significantly associated with depressive symptoms in older adults. The differences in physical function, ADL and depressive symptoms among older adults in 2015 and 2018 were further analyzed based on urban and rural stratification. Both physical dysfunction and ADL disability were significantly associated with depressive symptoms in rural older adults in 2015 and 2018. And in urban areas, ADL was found to be significantly associated with depressive symptoms in urban older adults. Multivariate logistic regression analysis demonstrated that ADL disability was significantly associated with depressive symptoms among older adults in both urban and rural areas. Physical dysfunction was only significant in rural areas with depressive symptoms. The alpha level was instead set to 0.05 for all statistical tests.ConclusionRural, female, 60–70 years of age, primary school or below, married, non-smoking, non-drinking, physical dysfunction, ADL disability and self-rated poor health make-up a higher proportion of depressed older adults. ADL disability and physical dysfunction were more likely to be associated with depressive symptoms in rural Chinese older adults. Therefore, the physical and mental health of rural elderly should be of concern. The rural older adults should receive additional support from the government and society
Association between gene expression and altered resting-state functional networks in type 2 diabetes
BackgroundType 2 diabetes (T2DM) is a polygenic metabolic disorder that accelerates brain aging and harms cognitive function. The underlying mechanism of T2DM-related brain functional changes has not been clarified.MethodsResting-fMRI data were obtained from 99 T2DM and 109 healthy controls (HCs). Resting-state functional connectivity networks (RSNs) were separated using the Independent Component Analysis (ICA) method, and functional connectivity (FC) differences between T2DM patients and HCs within the RSNs were detected. A partial least squares (PLS) regression was used to test the relation between gene expression from Allen Human Brain Atlas (AHBA) and intergroup FC differences within RSNs. Then the FC differences-related gene sets were enriched to determine the biological processes and pathways related to T2DM brain FC changes.ResultThe T2DM patients showed significantly increased FC in the left middle occipital gyrus (MOG) of the precuneus network (PCUN) and the right MOG / right precuneus of the dorsal attention network (DAN). FC differences within the PCUN were linked with the expression of genes enriched in the potassium channel and TrkB-Rac1 signaling pathways and biological processes related to synaptic function.ConclusionThis study linked FC and molecular alterations related to T2DM and suggested that the T2DM-related brain FC changes may have a genetic basis. This study hoped to provide a unique perspective to understand the biological substrates of T2DM-related brain changes
Evaluation of a village-based digital health kiosks program: A protocol for a cluster randomized clinical trial
Background
To address disparities in healthcare quality and access between rural and urban areas in China, reforms emphasize strengthening primary care and digital health utilization. Yet, evidence on digital health approaches in rural areas is lacking.
Objective
This study will evaluate the effectiveness of Guangdong Second Provincial General Hospital's Digital Health Kiosk program, which uses the Dingbei telemedicine platform to connect rural clinicians to physicians in upper-level health facilities and provide access to artificial intelligence-enabled diagnostic support. We hypothesize that our interventions will increase healthcare utilization and patient satisfaction, decrease out-of-pocket costs, and improve health outcomes.
Methods
This cluster randomized control trial will enroll clinics according to a partial factorial design. Clinics will be randomized to either a control arm with clinician medical training, a second arm additionally receiving Dingbei telemedicine training, or a third arm with monetary incentives for patient visits conducted through Dingbei plus all prior interventions. Clinics in the second and third arm will then be orthogonally randomized to a social marketing arm that targets villager awareness of the kiosk program. We will use surveys and Dingbei administrative data to evaluate clinic utilization, revenue, and clinician competency, as well as patient satisfaction and expenses.
Results
We have received ethical approval from Guangdong Second Provincial General Hospital (IRB approval number: GD2H-KY IRB-AF-SC.07-01.1), Peking University (IRB00001052-21007), and the University of North Carolina at Chapel Hill (323385). Study enrollment began April 2022.
Conclusions
This study has the potential to inform future telemedicine approaches and assess telemedicine as a method to address disparities in healthcare access.
Trial registration number: ChiCTR210005387
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