The Universal One-Loop Effective Action

We present the universal one-loop effective action for all operators of dimension up to six obtained by integrating out massive, non-degenerate multiplets. Our general expression may be applied to loops of heavy fermions or bosons, and has been checked against partial results available in the literature. The broad applicability of this approach simplifies one-loop matching from an ultraviolet model to a lower-energy effective field theory (EFT), a procedure which is now reduced to the evaluation of a combination of matrices in our universal expression, without any loop integrals to evaluate. We illustrate the relationship of our results to the Standard Model (SM) EFT, using as an example the supersymmetric stop and sbottom squark Lagrangian and extracting from our universal expression the Wilson coefficients of dimension-six operators composed of SM fields.Comment: 30 pages, v2 contains additional comments and corrects typos, version accepted for publication in JHE

Campylobacter jejuni transcriptome changes during loss of culturability in water

Background: Water serves as a potential reservoir for Campylobacter, the leading cause of bacterial gastroenteritis in humans. However, little is understood about the mechanisms underlying variations in survival characteristics between different strains of C. jejuni in natural environments, including water. Results: We identified three Campylobacter jejuni strains that exhibited variability in their ability to retain culturability after suspension in tap water at two different temperatures (4°C and 25°C). Of the three strains C. jejuni M1 exhibited the most rapid loss of culturability whilst retaining viability. Using RNAseq transcriptomics, we characterised C. jejuni M1 gene expression in response to suspension in water by analyzing bacterial suspensions recovered immediately after introduction into water (Time 0), and from two sampling time/temperature combinations where considerable loss of culturability was evident, namely (i) after 24 h at 25°C, and (ii) after 72 h at 4°C. Transcript data were compared with a culture-grown control. Some gene expression characteristics were shared amongst the three populations recovered from water, with more genes being up-regulated than down. Many of the up-regulated genes were identified in the Time 0 sample, whereas the majority of down-regulated genes occurred in the 25°C (24 h) sample. Conclusions: Variations in expression were found amongst genes associated with oxygen tolerance, starvation and osmotic stress. However, we also found upregulation of flagellar assembly genes, accompanied by down-regulation of genes involved in chemotaxis. Our data also suggested a switch from secretion via the sec system to via the tat system, and that the quorum sensing gene luxS may be implicated in the survival of strain M1 in water. Variations in gene expression also occurred in accessory genome regions. Our data suggest that despite the loss of culturability, C. jejuni M1 remains viable and adapts via specific changes in gene expression

Probing the Standard Model with Higgs signal rates from the Tevatron, the LHC and a future ILC

We explore the room for possible deviations from the Standard Model (SM) Higgs boson coupling structure in a systematic study of Higgs coupling scale factor benchmark scenarios using the latest signal rate measurements from the Tevatron and LHC experiments. We employ chi-squared fits performed with HiggsSignals, which takes into account detailed information on signal efficiencies and major correlations of theoretical and experimental uncertainties. All considered scenarios allow for additional non-standard Higgs boson decay modes, and various assumptions for constraining the total decay width are discussed. No significant deviations from the SM Higgs boson coupling structure are found in any of the investigated benchmark scenarios. We derive upper limits on an additional (undetectable) Higgs decay mode under the assumption that the Higgs couplings to weak gauge bosons do not exceed the SM prediction. We furthermore discuss the capabilities of future facilities for probing deviations from the SM Higgs couplings, comparing the high luminosity upgrade of the LHC with a future International Linear Collider (ILC), where for the latter various energy and luminosity scenarios are considered. At the ILC model-independent measurements of the coupling structure can be performed, and we provide estimates of the precision that can be achieved.Comment: 64 pages, 25 figures, 17 tables; v2: minor corrections in the text, references added. Matches published version on JHE