The Case for UHP Conditions in the Cuaba Terrane, Río San Juan Metamorphic Complex, Dominican Republic

From the Cuaba terrane in northern Dominican Republic. Ultrahigh pressure (UHP) conditions are indicated for the Cuaba terrane on the basis of phase relationships in garnet-bearing ultramafic rock. Dikes and orthocumulate textures indicate a magmatic origin. Mineral assemblages define a line of descent controlled by fractional crystallization. The original estimate of the magmatic conditions (P>3.4GPa, T>1550°C) was inferred previously from available high-P melting experiments in the CMAS system and high-P experimental determination of the sapphirine-out reaction in the MAS system. Revised estimates of magmatic conditions (P>3.2GPa, T>1500°C) take into account the influence of other components, especially Fe. We propose an origin in the mantle-wedge above a subduction zone. The rock was delivered to the subduction zone by forced convection in the mantle wedge (corner-flow), coupled with erosion of the hanging wall. Thermobarometry indicates >850°C and >3.4GPa when the ultramafic rock was incorporated into eclogite (deep-subducted oceanic crust). Evidence for UHP conditions in the retrograded eclogite is not obvious. Two types of symplectic intergrowths, plagioclase + clinopyroxene (Sym-I) and plagioclase + epidote (Sym-II), are interpreted as the products of the decomposition of two types of omphacite, Omp-I and Omp-II. Theoretically, Omp-II formed as the result of a retrograde reaction of the form, Omp-II + coesite = Omp-I + kyanite + /- garnet, according to which the maximum pressure for Omp-II is between ~2.8GPa (~850°C) and ~4.2GPa (~950°C), consistent with subsolidus conditions for the garnet-bearing ultramafic rocks. For eclogite, the highest-pressure mineral assemblage would have been Omp-I + kyanite + garnet + coesite

SUSY-Breaking Parameters from RG Invariants at the LHC

We study Renormalization Group invariant (RGI) quantities in the Minimal Supersymmetric Standard Model and show that they are a powerful and simple instrument for testing high scale models of supersymmetry (SUSY)-breaking. For illustration, we analyze the frameworks of minimal and general gauge mediated (MGM and GGM) SUSY-breaking, with additional arbitrary soft Higgs mass parameters at the messenger scale. We show that if a gaugino and two first generation sfermion soft masses are determined at the LHC, the RGIs lead to MGM sum rules that yield accurate predictions for the other gaugino and first generation soft masses. RGIs can also be used to reconstruct the fundamental MGM parameters (including the messenger scale), calculate the hypercharge D-term, and find relationships among the third generation and Higgs soft masses. We then study the extent to which measurements of the full first generation spectrum at the LHC may distinguish different SUSY-breaking scenarios. In the case of MGM, although most deviations violate the sum rules by more than estimated experimental errors, we find a 1-parameter family of GGM models that satisfy the constraints and produce the same first generation spectrum. The GGM-MGM degeneracy is lifted by differences in the third generation masses and the messenger scales.Comment: (v1) 30 pages; (v2) mislabeling in figs 2 and 3 corrected, version accepted for publication in Phys. Rev.

Determining the Structure of Supersymmetry-Breaking with Renormalization Group Invariants

If collider experiments demonstrate that the Minimal Supersymmetric Standard Model (MSSM) is a good description of nature at the weak scale, the experimental priority will be the precise determination of superpartner masses. These masses are governed by the weak scale values of the soft supersymmetry (SUSY)-breaking parameters, which are in turn highly dependent on the SUSY-breaking scheme present at high scales. It is therefore of great interest to find patterns in the soft parameters that can distinguish different high scale SUSY-breaking structures, identify the scale at which the breaking is communicated to the visible sector, and determine the soft breaking parameters at that scale. In this work, we demonstrate that 1-loop Renormalization Group~(RG) invariant quantities present in the MSSM may be used to answer each of these questions. We apply our method first to generic flavor-blind models of SUSY-breaking, and then examine in detail the subset of these models described by General Gauge Mediation and the constrained MSSM with non-universal Higgs masses. As RG invariance generally does not hold beyond leading-log order, we investigate the magnitude and direction of the 2-loop corrections. We find that with superpartners at the TeV scale, these 2-loop effects are either negligible, or they are of the order of optimistic experimental uncertainties and have definite signs, which allows them to be easily accounted for in the overall uncertainty.Comment: v2 -- references added, version to be published in PRD; 40 page

Using Rheo-Small-Angle Neutron Scattering to Understand How Functionalised Dipeptides Form Gels

We explore the use of rheo-small-angle neutron scattering as a method to collect structural information from neutron scattering simultaneously with rheology to understand how low-molecular-weight hydrogels form and behave under shear. We examine three different gelling hydrogel systems to assess what structures are formed and how these influence the rheology. Furthermore, we probe what is happening to the network during syneresis and why the gels do not recover after an applied strain. All this information is vital when considering gels for applications such as 3D-printing and injection

Decuplet Baryon Structure from Lattice QCD

The electromagnetic properties of the SU(3)-flavor baryon decuplet are examined within a lattice simulation of quenched QCD. Electric charge radii, magnetic moments, and magnetic radii are extracted from the E0 and M1 form factors. Preliminary results for the E2 and M3 moments are presented giving the first model independent insight to the shape of the quark distribution in the baryon ground state. As in our octet baryon analysis, the lattice results give evidence of spin-dependent forces and mass effects in the electromagnetic properties. The quark charge distribution radii indicate these effects act in opposing directions. Some baryon dependence of the effective quark magnetic moments is seen. However, this dependence in decuplet baryons is more subtle than that for octet baryons. Of particular interest are the lattice predictions for the magnetic moments of $\Omega^-$ and $\Delta^{++}$ for which new recent experimental measurements are available. The lattice prediction of the $\Delta^{++}/p$ ratio appears larger than the experimental ratio, while the lattice prediction for the $\Omega^-/p$ magnetic moment ratio is in good agreement with the experimental ratio.Comment: RevTeX manuscript, 34 pages plus 21 figures (available upon request

A feasibility study of signed consent for the collection of patient identifiable information for a national paediatric clinical audit database

Objectives: To investigate the feasibility of obtaining signed consent for submission of patient identifiable data to a national clinical audit database and to identify factors influencing the consent process and its success. Design: Feasibility study. Setting: Seven paediatric intensive care units in England. Participants: Parents/guardians of patients, or patients aged 12-16 years old, approached consecutively over three months for signed consent for submission of patient identifiable data to the national clinical audit database the Paediatric Intensive Care Audit Network (PICANet). Main outcome measures: The numbers and proportions of admissions for which signed consent was given, refused, or not obtained (form not returned or form partially completed but not signed), by age, sex, level of deprivation, ethnicity (South Asian or not), paediatric index of mortality score, length of hospital stay (days in paediatric intensive care). Results: One unit did not start and one did not fully implement the protocol, so analysis excluded these two units. Consent was obtained for 182 of 422 admissions (43%) (range by unit 9% to 84%). Most (101/182; 55%) consents were taken by staff nurses. One refusal (0.2%) was received. Consent rates were significantly better for children who were more severely ill on admission and for hospital stays of six days or more, and significantly poorer for children aged 10-14 years. Long hospital stays and children aged 10-14 years remained significant in a stepwise regression model of the factors that were significant in the univariate model. Conclusion: Systematically obtaining individual signed consent for sharing patient identifiable information with an externally located clinical audit database is difficult. Obtaining such consent is unlikely to be successful unless additional resources are specifically allocated to training, staff time, and administrative support

L1551NE - Discovery of a Binary Companion

L1551NE is a very young (class 0 or I) low-mass protostar located close to the well-studied L1551 IRS5. We present here evidence, from 1.3mm continuum interferometric observations at ~1'' resolution, for a binary companion to L1551NE. The companion, whose 1.3mm flux density is ~1/3 that of the primary component, is located 1.43'' (~230 A.U. at 160pc) to the southeast. The millimeterwave emission from the primary component may have been just barely resolved, with deconvolved size ~0.82"x0.70" (~131x112 A.U.). The companion emission was unresolved (<100 A.U.). The pair is embedded within a flattened circum-binary envelope of size ~5.4'' x 2.3'' (~860 x 370 A.U.). The masses of the three components (i.e. from the cicumstellar material of the primary star and its companion, and the envelope) are approximately 0.044, 0.014 and 0.023 Mo respectively.Comment: 8 pages, 1 figur

Listeriolysin S, a Novel Peptide Haemolysin Associated with a Subset of Lineage I Listeria monocytogenes

peer-reviewedStreptolysin S (SLS) is a bacteriocin-like haemolytic and cytotoxic virulence factor that plays a key role in the virulence of Group A Streptococcus (GAS), the causative agent of pharyngitis, impetigo, necrotizing fasciitis and streptococcal toxic shock syndrome. Although it has long been thought that SLS and related peptides are produced by GAS and related streptococci only, there is evidence to suggest that a number of the most notorious Gram-positive pathogenic bacteria, including Listeria monocytogenes, Clostridium botulinum and Staphylococcus aureus, produce related peptides. The distribution of the L. monocytogenes cluster is particularly noteworthy in that it is found exclusively among a subset of lineage I strains; i.e., those responsible for the majority of outbreaks of listeriosis. Expression of these genes results in the production of a haemolytic and cytotoxic factor, designated Listeriolysin S, which contributes to virulence of the pathogen as assessed by murine- and human polymorphonuclear neutrophil–based studies. Thus, in the process of establishing the existence of an extended family of SLS-like modified virulence peptides (MVPs), the genetic basis for the enhanced virulence of a proportion of lineage I L. monocytogenes may have been revealed.Work is funded by the Irish Government under the National Development Plan, through a Science Foundation Ireland Investigator award to CH, PR and PC (06/IN.1/B98)