Extension de la réaction de Todd aux 1-hydrido-1-organyloxybicyclo-phosphoranes porteurs d'une fonction amine secondaire

The extension of the Todd reaction to 1-hydrido-1-organyloxybicyclophosphoranes 2–5 bearing a secondary amine group leads to a cyclic bis(bicyclophosphoranes) 2d–5d as well as to a symmetric bicyclophosphoranes 6, 7, 8 in which the H—P atom has been substituted by the organyloxy group. These last compounds are a good synthons for the preparation of new bicyclophosphoranes containing macrocycles

On the extension of the atherton-todd reaction to the pentacoordinated phosphorus compounds. synthesis of new bicyclophosphoranes containing macrocycles

The three macrocycles 5, 6, 7 with 10, 16 and 22 links, bearing two bicyclophosphoranes moieties are synthesized by the Atherton-Todd reaction carried out with the bis(hydridobicyclophosphoranes) 2, 3, 4. This result confirms the generality of this reaction leading to new families of bis(bicyclophosphoranes) containing macrocycles