The Effect of the 1998 Master Settlement on Prenatal Smoking

The Master Settlement Agreement (MSA) between the major tobacco companies and 46 states created an abrupt 45 cent (21%) increase in cigarette prices in November, 1998. Earlier estimates of the elasticity of prenatal smoking implied that the price rise would reduce prenatal cigarette smoking by 7% to 21%. Using birth records on 10 million U.S. births between January 1996 and February 2000, we examined the change in smoking during pregnancy and conditional smoking intensity in response to the MSA. Overall, adjusting for secular trends in smoking, prenatal smoking declined much less than predicted in response to the MSA.

Infrastructure in a Structural Model of Economic Growth

Researchers, commentators, and politicians have devoted steadily more attention to infrastructure in response to claims that inadequate accumulation of public capital has contributed to substandard U.S. economic growth. Despite this, the link between infrastructure and productivity growth remains controversial. In this regard, it is somewhat surprising that infrastructure research has developed in isolation from the large literature on economic growth. We develop a neoclassical growth model that explicitly incorporates infrastructure and is designed to provide a tractable framework within which to analyze the empirical importance of public capital accumulation to productivity growth. We find little support for claims of a dramatic productivity boost from increased infrastructure outlays. In a specification designed to provide an upper bound for the influence of infrastructure, we estimate that raising the rate of infrastructure investment would have had a negligible impact on annual productivity growth between 1971 and 1986.

The rise of European Commercial Association during the Middle Ages

The unity of Western Europe has not yet approached the political, economic and religious entity realized under the Roman Empire. Nor is it likely to duplicate such a centralized and authoritative basis of organization. It is the purpose of this paper to explore European economic association on the basis of co-operation rather than dominance. For this purpose historical cornerstones of economic co-operation and commercial endeavor will be discussed. ... Among them the individuals and groups who pursued trade not only revived the collapsed commerce known to the Roman world, but provided the framework for modern commercial and financial activity and cooperation. Their motives were, no doubt, selfish, since basic human self-interest is a commanding force. The results, however, were liberating, both socially and politically, as well as economically. Thus the Medieval commercial heritage is enjoyed not only in the lands of North and West Europe, but in the Western Hemisphere as well today. It seems singularly important in explaining political as well as economic developments of the twentieth century

Student Mathematics Performance in Year One Implementation of Teach to One: Math

This report examines mathematics test data from the first year of implementation (2012-13) of the Teach to One: Math (TtO) approach in seven urban middle schools in Chicago, New York City, and Washington D.C. Researchers addressed the question: How did Tto students' growth on the Measures of Academic Progress (MAP) mathematics assessment compare with national norms?To answer this question, the researchers analyzed student performance on the MAP test, an established instrument developed by the Northwest Evaluation Association (NWEA). The researchers then compared these results to the national norms published by NWEA (2011). Please note that these analyses cannot attribute Tto student results to the TtO model: the data available did not permit the use of an experimental design, which would be necessary to establish a link between the implementation of the program and the student test results. While the TtO results are promising, its performance beyond one year should be analyzed using an experimental design, in order to remove unmeasured differences between TtO students and schools with an appropriate comparison sample

Climate Change Impacts and Projections for the Greater Boston Area: Findings of the Greater Boston Research Advisory Group Report

During the writing of the inaugural Boston Research Advisory Group (BRAG) report both NASA and NOAA announced that 2015 was the warmest year on record, beating the previous record set in 2014, by 0.29 °F. Just five years later (during the writing of this report), NASA announced that 2020 had tied 2016 for the warmest year, breaking the previous record by a stunning 1.84 °F, and that the last seven years have been the warmest seven-year period on record. These observations support the assertion made in the sixth and most recent assessment by the Intergovernmental Panel on Climate Change , which states, “It is unequivocal that human influence has warmed the atmosphere, ocean and land. Widespread and rapid changes in the atmosphere, ocean, cryosphere and biosphere have occurred.” Hence, the question is not whether the climate is changing, but what we’re going to do about it. At a minimum, we must focus efforts to get to net zero greenhouse gas (GHG) by 2050. It’s not too late to achieve that goal, but time is running out for us to prevent the worst-case scenarios suggested here. This report is broken into four chapters and summarizes the most recent (as of late 2021) scientific understanding of climate risk factors pertinent to Greater Boston

A systematic review of pharmacovigilance systems in developing countries using the WHO pharmacovigilance indicators

BACKGROUND: In the context of the growth of pharmacovigilance (PV) among developing countries, this systematic review aims to synthesise current research evaluating developing countries’ PV systems’ performance. METHODS: EMBASE, MEDLINE, CINAHL Plus and Web of Science were searched for peer-reviewed studies published in English between 2012 and 2021. Reference lists of included studies were screened. Included studies were quality assessed using Hawker et al.'s nine-item checklist; data were extracted using the WHO PV indicators checklist. Scores were assigned to each group of indicators and used to compare countries’ PV performance. RESULTS: Twenty-one unique studies from 51 countries were included. Of a total possible quality score of 36, most studies were rated medium (n = 7 studies) or high (n = 14 studies). Studies obtained an average score of 17.2 out of a possible 63 of the WHO PV indicators. PV system performance in all 51 countries was low (14.86/63; range: 0–26). Higher average scores were obtained in the ‘Core’ (9.27/27) compared to ‘Complementary’ (5.59/36) indicators. Overall performance for ‘Process’ and ‘Outcome’ indicators was lower than that of ‘Structural’. CONCLUSION: This first systematic review of studies evaluating PV performance in developing countries provides an in-depth understanding of factors affecting PV system performance. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s43441-022-00415-y

Climate Change in the Piscataqua/Great Bay Region: Past, Present, and Future

Earth ’s climate changes. It always has and always will. However, an extensive body of scientific evidence indicates that human activities are now a significant force driving change in the Earth’s climate system. This report describes how the climate of the Piscataqua/Great Bay region of coastal New Hampshire in the United States has changed over the past century and how the future climate of the region will be affected by human activities that are warming the planet. Overall, the region has been getting warmer and wetter over the last century, and the rate of change has increased over the last four decades. To generate future climate projections for the region, simulated temperature and precipitation from four general circulation models were fitted to local, long-term weather observations. Unknowns regarding future fossil fuel consumption were accounted for by using two future emissions scenarios. As greenhouse gases continue to accumulate in the atmosphere, temperatures will rise, extreme heat days are projected to occur more often and will be hotter, extreme cold temperatures are projected to occur less often, and cold days will be warmer.. Annual average precipitation is projected to increase 12 to 17% by end-of-century and the region can expect to see more extreme precipitation events in the future. Tidal gauge data indicates relative sea level at Portsmouth has risen 0.7 inches per decade over the past eight decades. Projected sea level rise of 1.7 to 6.3 feet will result in higher storm surges and more frequent flooding in coastal New Hampshire