Dosithei magistri liber III, continens divi Adriani imp. sententias et epistolas

Melior Hamenvelto Goldastus maximam partem auxit, emendavit, illustravitSignatures : A-D⁸, E

Hermeneumata Vaticana / digital edition published by digilibLT digital library of late-Latin texts

Correzione linguistica Paola Miotto Codifica XML Nadia Rosso HomePage del progetto: https://digiliblt.uniupo.it/ Documentazione: https://digiliblt.uniupo.it/progetto.ph

Hermeneumata Amploniana / digital edition published by digilibLT digital library of late-Latin texts

Correzione linguistica Benedetta Montorsi e Beatrice Strona Codifica XML Nadia Rosso HomePage del progetto: https://digiliblt.uniupo.it/ Documentazione: https://digiliblt.uniupo.it/progetto.ph

Fragmentum Parisinum / digital edition published by digilibLT digital library of late-Latin texts

Correzione linguistica Beatrice Strona Codifica XML Nadia Rosso HomePage del progetto: https://digiliblt.uniupo.it/ Documentazione: https://digiliblt.uniupo.it/progetto.ph

Hermeneumata Bruxellensia / digital edition published by digilibLT digital library of late-Latin texts

Correzione linguistica Dario Gabutti Codifica XML Nadia Rosso HomePage del progetto: https://digiliblt.uniupo.it/ Documentazione: https://digiliblt.uniupo.it/progetto.ph

Ars Grammatica / digital edition published by digilibLT digital library of late-Latin texts

transcodifica di base da rtf a xml-tei Piero Colombo - Step srl Testo Marinone, GL-CD adeguato su ed. Bonnet Adeguamento testo su nuova edizione Gianmario Cattaneo Controllo marcatura XML-TEI Alice Borgna HomePage del progetto: https://digiliblt.uniupo.it/ Documentazione: https://digiliblt.uniupo.it/progetto.ph

Hermeneumata Leidensia / digital edition published by digilibLT digital library of late-Latin texts

Correzione linguistica Nadia Rosso Codifica XML Nadia Rosso HomePage del progetto: https://digiliblt.uniupo.it/ Documentazione: https://digiliblt.uniupo.it/progetto.ph

Hermeneumata Monacensia / digital edition published by digilibLT digital library of late-Latin texts

Correzione linguistica Alberto Burocco, Celestina Calabrese (ed. Goetz); Benedetta Montorsi (ed. Dickey) Codifica XML Nadia Rosso HomePage del progetto: https://digiliblt.uniupo.it/ Documentazione: https://digiliblt.uniupo.it/progetto.ph

A randomized trial of methotrexate versus azathioprine for severe atopic eczema

Patients with severe atopic eczema frequently require systemic treatment to control their disease. Methotrexate and azathioprine are proposed as off-label treatment options, but direct comparisons are lacking. We sought to compare the efficacy and safety of methotrexate versus azathioprine in adults with severe atopic eczema. Patients with severe atopic eczema were randomly assigned in a 1:1 ratio to receive either methotrexate (dosage, 10-22.5 mg/wk) or azathioprine (dosage, 1.5-2.5 mg/kg/d) for 12 weeks, followed by a 12-week follow-up period. Primary outcome was the mean change in the severity scoring of atopic dermatitis index after 12 weeks. Efficacy assessors blinded for allocation of treatment were used to perform clinical outcome assessment. Analyses were done on an intention-to-treat basis. Of the 45 patients screened, 42 were included. At week 12, patients in the methotrexate group had a mean relative reduction in the severity scoring of atopic dermatitis index of 42% (SD, 18%) compared with 39% (SD, 25%) in the azathioprine group (P = .52). Proportions of patients achieving at least mild disease and reductions on impact of quality of life, symptoms, and levels of thymus and activation-regulated chemokine were similar in both groups at weeks 12 and 24. No statistically significant differences were found in the number and severity of adverse events. Abnormalities in blood count were more common in the azathioprine group. No serious adverse events occurred. Both treatments achieved clinically relevant improvement and were safe in the short term. Methotrexate and azathioprine are appropriate options for the treatment of severe atopic eczem