Environmental SLAPPs in the UK: threat or opportunity?

Strategic lawsuits against public participation (SLAPPs) brought against the environmental movement in the UK since the 1990s are examined. SLAPPs, a form of Green backlash, have been mobilised across a wide range of policy areas that have seen vigorous campaigning and protest by the movement, including roads, GMOs and, more recently, climate change. SLAPPs are typically regarded as a threat, designed to close down democratic free speech and protest. However, in the UK, there are some notable cases where the environmental movement has been able to use agency to convert what may appear as a legal threat into a positive legal or media opportunity

Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion–Positive Supratentorial Ependymomas

Molecular groups of supratentorial ependymomas comprise tumors with ZFTA-RELA or YAP1-involving fusions and fusion-negative subependymoma. However, occasionally supratentorial ependymomas cannot be readily assigned to any of these groups due to lack of detection of a typical fusion and/or ambiguous DNA methylation-based classification. An unbiased approach with a cohort of unprecedented size revealed distinct methylation clusters composed of tumors with ependymal but also various other histological features containing alternative translocations that shared ZFTA as a partner gene. Somatic overexpression of ZFTA-associated fusion genes in the developing cerebral cortex is capable of inducing tumor formation in vivo, and cross-species comparative analyses identified GLI2 as a key downstream regulator of tumorigenesis in all tumors. Targeting GLI2 with arsenic trioxide caused extended survival of tumor-bearing animals, indicating a potential therapeutic vulnerability in ZFTA fusion-positive tumors

Eco-politics beyond the paradigm of sustainability: A conceptual framework and research agenda

This contribution sketches a conceptual framework for the analysis of the post-ecologist era and outlines a research agenda for investigating its politics of unsustainability. The article suggests that this new era and its particular mode of eco-politics necessitate a new environmental sociology. Following a review of some achievements and limitations of the paradigm of sustainability, the concept of post-ecologism is related to existing discourses of the ‘end of nature’, the ‘green backlash’ and the ‘death of environmentalism’. The shifting terrain of eco-politics in the late-modern condition is mapped and an eco-sociological research programme outlined centring on the post-ecologist question: How do advanced modern capitalist consumer democracies try and manage to sustain what is known to be unsustainable

Network Movement in the Czech Republic: Peturbating Prague

The prominence of global fault lines organised around the environment and social justice revealed through global social movement activity has significant implications for established approaches to political and social science. In particular, the rise of network analyses and the increasing attention to complexity theory within the social sciences represent profound challenges to established paradigms. This paper engages with this intellectual terrain utilising the 2000 Prague IMF/WB action to illustrate the unintended and largely unobserved political consequences and implications of global movement for established approaches within the political and policy sciences. It is argued that the default assumption that social movement activity automatically revolves around nationally defined political opportunity structures overlooks the significance of movement capacity building activities within this ‘shadow realm’—the most visible element of which can be seen in the activities of the European Social Forum. The paper draws on data gathered under an ESRC small grant and a Leverhulme Fellowship on Leadership within movements