Additional file 1: of Epigenome-wide association study of metabolic syndrome in African-American adults

Table S1. HyperGEN family structure. Table S2. Baseline characteristics of REGARDS study participants. Figure S1. Epigenome-wide association for metabolic syndrome among African-Americans in HyperGEN study (N = 606). Figure S2. Differences in mean DNA methylation (%) of (A) cg06500161 in ABCG1 and of (B) cg06638433 in IGF2BP1 gene by metabolic syndrome and components. (PDF 1194 kb

Characteristics of Study Participants.

<p>Age indicates mean age. Model indicates analysis method: C, Cox proportional hazards regression; L, logistic regression. For prevalence of antihypertensive medication use ACE indicates Angiotensin-converting enzyme inhibitor (or angiotensin receptor blocker); BB, beta-blocker; CCB, calcium channel blocker; Diuretics, thiazide diuretics.For studies analyzed with logistic regression, summaries are provided separately for cases and controls.</p><p>Characteristics of Study Participants.</p

Plots show the individual interaction p-values based on Stage I (indicated as solid dots) or Stage I + Stage II meta-analysis (indicated as outlined dots with “+” symbol) against their genomic position for the combined cardiovascular disease (CVD) outcome for the four antihypertensive medication exposures: (a) Angiotensin-converting enzyme (ACE) inhibitors, (b) Beta-blockers, (c) Calcium Channel Blockers, and (d) Thiazide Diuretics.

<p>Within each chromosome, shown on the x-axis, the results are plotted left to right from the p-terminal end. The nearest genes are indicated for variants with an interaction p-value less than 1×10⁻⁵ in the meta-analysis.</p

Intervention dans le Podcast les Arts du FLE pour faire le point sur la perspective actionnelle en classe de langues

Ce podcast est disponible en ligne, à l'adresse suivante :https://agi.to/podcast/arts-du-fle-08-actionne-ton-approche/Ce numéro 8 des Arts du FLE (émission spécialisée en FLE) propose un dossier spécial approches pédagogiques et perspective actionnelle. J'en suis l'invitée et j'y réponds de manière détaillée pendant près d'une heure aux questions de l'animateur et créateur de ce Podcast, Sébastien Durietz (en poste actuellement à l'ONU, à New-York)

Additional file 6: Figures S1–S4. of DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

(PDF 1036 kb

Additional file 9: Table S8. of DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Significant methylation-expression results and corresponding expression-CRP results for the replicated CpGs. (XLSX 11 kb

Additional file 10: Table S9. of DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Significant associations between DNA methylation and corresponding nearby genetic variants and between the genetic variant and CRP in the largest published GWAS of CRP (n = 66,185). (XLSX 12 kb