78 research outputs found

    Improved Thermal Transmittance Measurement with HFM Technique on Building Envelopes in the Mediterranean Area

    Get PDF
    Abstract Although the designed theoretical value of U can be derived from the thermal parameters of layers composing an opaque element, according to ISO 6946:2007, measurements are necessary to confirm the expected behaviour. Currently, the measurements of thermal transmittance based on Heat Flow Meter method (HFM) and according to standard ISO 9869-1:2014 are widely accepted. Anyway, some issues related to difficulties in measurements are present: the roughness of wall surfaces, the proper contact between the heat flow plate and the temperature probes with wall surfaces, undesired changes in weather conditions. This work presents the results obtained in thermal transmittance measurements with a modified HFM method, widely described in this paper. Differences between U-values obtained with the modified HFM method and theoretical ones were in the range 0.6 - 6.5 %. Moreover, the modified HFM method provided a result closer to the theoretical one, when compared to that obtained with standard HFM method (discrepancy with theoretical value were 0.6% and 16.4%, respectively)

    A dataset of future daily weather data for crop modelling over Europe derived from climate change scenarios

    Get PDF
    Coupled atmosphere-ocean general circulation models (AOGCMs, or just GCMs for short) simulate different realizations of possible future climates at global scale under contrasting scenarios of greenhouse gases emissions. While these datasets provide several meteorological variables as output, but two of the most important ones are air temperature at the Earth's surface and daily precipitation. GCMs outputs are spatially downscaled using different methodologies, but it is accepted that such data require further processing to be used in impact models, and particularly for crop simulation models. Daily values of solar radiation, wind, air humidity, and, at times, rainfall may have values which are not realistic, and/or the daily record of data may contain values of meteorological variables which are totally uncorrelated. Crop models are deterministic, but they are typicallyrun in a stochastic fashion by using a sample of possible weather time series that can be generated using stochastic weather generators. With their random variability, these multiple years of weather data can represent the time horizon of interest. GCMs estimate climate dynamics, hence providing unique time series for a given emission scenario; the multiplicity of years to evaluate a given time horizon is consequently not available from such outputs. Furthermore, if the time horizons of interest are very close (e.g. 2020 and 2030), averaging only the non-overlapping years of the GCM weather variables time series may not adequately represent the time horizon; this may lead to apparent inversions of trends, creating artefacts also in the impact model simulations. This paper presents a database of consolidated and coherent future daily weather data covering Europe with a 25 km grid, which is adequate for crop modelling in the near-future. Climate data are derived from the ENSEMBLES downscaling of the HadCM3, ECHAM5, and ETHZ realizations of the IPCC A1B emission scenario, using for HadCM3 two different regional models for downscaling. Solar radiation, wind and relative air humidity weather variables where either estimated or collected from historical series, and derived variables reference evapotranspiration and vapour pressure deficit were estimated from other variables, ensuring consistency within daily records. Synthetic time series data were also generated using the weather generator ClimGen. All data are made available upon request to the European Commission Joint Research Centre's MARS unit.JRC.H.7-Climate Risk Managemen

    Liver eosinophilic infiltrate is a significant finding in patients with chronic hepatitis C.

    Get PDF
    Eosinophilic infiltrate of liver tissue is described in primary cholestatic diseases, hepatic allograft rejection and drug-induced liver injury, but its significance and its implications in chronic hepatitis C are unknown. The aim of this study was to investigate the clinical significance of eosinophilic liver infiltrate in patients with chronic hepatitis C. We retrospectively evaluated 147 patients with chronic hepatitis C. The presence of eosinophilic infiltrate was investigated in liver biopsies, and a numeric count of eosinophilic leucocytes in every portal tract was assessed. An eosinophilic infiltrate of liver tissue (≥3 cells evaluated in the portal/periportal spaces) was observed in 46 patients (31%), and patients who consumed drugs had an odds ratio (OR) of 4.02 (95% CI: 1.62-9.96) to have an eosinophilic infiltrate in liver biopsy. By logistic regression analysis, the presence of steatosis was independently associated with eosinophilic infiltrate (OR 5.86; 95% CI: 2.46-13.96) and homeostasis model assessment-score (OR 1.18; 95% CI: 1.00-1.39). Logistic regression analysis also showed that fibrosis staging ≥ 2 by Scheuer score was associated with grading >1 by Scheuer score (OR 6.82; 95% CI 2.46-18.80) and eosinophilic infiltrate (OR 4.00; 95% CI 1.23-12.91). In conclusion, we observed that the eosinophilic infiltrate of liver tissue was significantly more frequent in patients who assumed drugs, and found a significant association between eosinophilic infiltrate, liver steatosis and liver fibrosis. These preliminary data could lead to a constant assumption of drugs as a co-factor of eosinophils-mediated liver injury in chronic hepatitis

    Different pH requirements are associated with divergent inhibitory effects of chloroquine on human and avian influenza A viruses

    Get PDF
    Chloroquine is a 4-aminoquinoline previously used in malaria therapy and now becoming an emerging investigational antiviral drug due to its broad spectrum of antiviral activities. To explore whether the low pH-dependency of influenza A viruses might affect the antiviral effects of chloroquine at clinically achievable concentrations, we tested the antiviral effects of this drug on selected human and avian viruses belonging to different subtypes and displaying different pH requirements. Results showed a correlation between the responses to chloroquine and NH4Cl, a lysosomotropic agent known to increase the pH of intracellular vesicles. Time-of-addition experiments showed that the inhibitory effect of chloroquine was maximal when the drug had been added at the time of infection and was lost after 2 h post-infection. This timing approximately corresponds to that of virus/cell fusion. Moreover, there was a clear correlation between the EC50 of chloroquine in vitro and the electrostatic potential of the HA subunit (HA2) mediating the virus/cell fusion process. Overall, the present study highlights the critical importance of a host cell factor such as intravesicular pH in determining the anti-influenza activity of chloroquine and other lysosomotropic agents

    Influence of Carding and Pressing on Hygrothermal Properties and Fire Reaction of Hemp Fiber Nonwoven Mats

    Get PDF
    This article depicts the effect of carding and pressing on hygrothermal properties of hemp fibers nonwoven mats, trying to understand if their implementation can improve their behavior when employed as insulation materials in buildings. Hemp fibers belonging to Cannabis Sativa species and coming from local area (Apulia - Italy) were examined, then samples of carded and pressed hemp fibers nonwoven mats were prepared. According to European standards, the thermal conductivity, the vapor permeability and the fire reaction of hemp fibers samples were measured. Results were compared to each other and with those of a commercial nonwoven mat made with hemp (90 wt. %) and synthetic fibers (10 wt. %), used as reference. We observed that carded and pressed hemp fibers were characterized by a lower thermal conductivity when compared to unprocessed hemp fibers, likely because the removing of wood elements. On the other hand, not processed hemp fibers show higher breathability when compared to carded and pressed ones, as well as with respect to the commercial nonwoven mat. Moreover, it was proved that the absence of synthetic commingled fibers in hemp fibers allows a better behavior in fire reaction. At last, the improvement in terms of insulation properties of a hollow brick when filled with hemp fibers was verified, by comparing the thermal conductivities of an empty and a filled hollow brick; as expected, the filled hollow brick shows a lower thermal conductivity, underlining the effectiveness of hemp fibers as insulation material

    Transmission of Hemagglutinin D222G Mutant Strain of Pandemic (H1N1) 2009 Virus

    Get PDF
    A pandemic (H1N1) 2009 virus strain carrying the D222G mutation was identified in a severely ill man and was transmitted to a household contact. Only mild illness developed in the contact, despite his obesity and diabetes. The isolated virus reacted fully with an antiserum against the pandemic vaccine strain

    Assessing agriculture vulnerabilities for the design of effective measures for adaptation to climate change (AVEMAC project)

    Get PDF
    This final report of the AVEMAC study presents an assessment of the potential vulnerability of European agriculture to changing climatic conditions in the coming decades. The analysis is based on weather data generated from two contrasting realizations of the A1B emission scenario of the Intergovernmental Panel on Climate Change (IPCC) for the time horizons 2020 and 2030. These two realizations (obtained from two different general circulation models, downscaled using regional climate models and biascorrected) represent the warmest and coldest realizations of the A1B scenario over Europe as estimated by the ENSEMBLES project. The future weather data fed two types of analyses. The first analysis consisted in computing static agro-meteorological indicators as proxies of potential vulnerabilities of agricultural systems, expressed as changes in the classification of agricultural areas in Europe under climate constraints. The second analysis relied on biophysical modelling to characterize crop specific plant responses derived from crop growth simulations at different production levels (potential production, water-limited production, and production limited by diseases). Assessing the importance of vulnerability to climate change requires not only the localisation of relative yield changes, but also the analysis of the impact of the change on the acreage affected. Consequently, the simulation results of the impact assessment on crops were further processed to estimate the potential changes in production at sub-national (NUTS2) level. This was achieved by relating the simulation results to farm typologies in order to identify which types of systems are likely to be affected by reductions in production. The analyses of this study must be considered as a first step only, since they have neither included adaptation strategies that the farmer can take in response to changes in climate, nor a bio-economic evaluation of estimated vulnerabilities. Therefore, the main aspects and the requirements for a possible future integrated analysis at EU27 level to address climate change and agriculture with the target of providing policy support are also presented in this report. Eventually the results of this study shall help the formulation of appropriate policy options and the development of adequate policy instruments to support the adaptation to climate change of the EU agricultural sector.JRC.H.4-Monitoring Agricultural Resource

    Estudo comparativo da força muscular da mão entre cadetes homens e mulheres da Força Aérea Brasileira: a comparative study between men and women

    Get PDF
    O objetivo do estudo foi quantificar a força muscular da mão, nos movimentos de preensão palmar e três tipos de pinça, comparando os cadetes homens e mulheres. Foram avaliados 31 cadetes da Academia da Força Aérea Basileira, sendo 17 homens e 14 mulheres, com os dinamômetros Jamar e Preston Pinch Gauge. A média de preensão das mulheres foi de 31,4 kgf no lado dominante e 29,3 kgf no lado não-dominante; nos homens, foi 43,6 e 41,2 kgf, respectivamente (pThe aim of this study was to quantify the hand muscle strength during grip and pinch movements, and to compare results between men and women. Thirty-one cadet pilots (17 men and 14 women) from the Brazilian Air Force Academy were assessed by means of Jamar dynamometer (grip) and Preston Pinch Gauge (pinch). Female cadets mean grip was 31.4 kgf at dominant hand and 29.3 kgf at non-dominant hand; in male subjects, corresponding values were 43.6 kgf and 41.2 kgf. Mean female lateral pinch at the dominant hand was 7.4 kgf and men's, 10.2 kgf (
    corecore