The role of diploma brand in the prospect of demographic slump in Poland (2010-2020)

Przedmiotem artykułu są zmiany w polskim szkolnictwie wyższym wynikające z umasowienia szkolnictwa wyższego, przeobrażeń strukturalnych gospodarki w kierunku modelu postindustrialnego oraz liberalnych reform sektora publicznego. Celem analiz jest pokazanie, że w warunkach rosnącej konkurencji coraz większe znaczenie będzie miała marka dyplomu uczelni. W Polsce marka dyplomu uczelni nie odgrywała dotąd znaczącej roli, ponieważ zaległości edukacyjne, a przede wszystkim koniunktura demograficzna, zapewniały wystarczająco wysoki poziom popytu na usługi edukacyjne w szkolnictwie wyższym. Ten okres już minął i w nadchodzących latach rywalizacja o studentów będzie coraz większa, a marka dyplomu już zaczyna odgrywać decydującą rolę w tym, które uczelnie pozostaną na rynku edukacyjnym, a które będą musiały przejść głęboką restrukturyzację lub po prostu zniknąć z rynku.This article focuses on changes in Poland’s higher education resulting from: the massification of higher education, structural transformations within the economy towards the post-industrial model, and liberał reforms of the public sector. The aim of this analysis is to show that the brand of a university diploma will become increasingly important in the context of growing competition. To date, the brand of a diploma has not played a significant role in Poland’s higher education as educational insufficiencies and, most notably, positive demographic trends, ensured a sufficient demand for higher education services. As this period is now gone, the coming years will see growing competition for students, and the brand of a diploma will determine (as we are beginning to see) which universities will survive on the educational market and which ones will have to undergo deep restructuring or, simply, disappear from the market

A Spectroscopic and Photometric Investigation of the Mercury-Manganese Star KIC 6128830

The advent of space-based photometry provides the opportunity for the first precise characterizations of variability in Mercury-Manganese (HgMn/CP3) stars, which might advance our understanding of their internal structure. We have carried out a spectroscopic and photometric investigation of the candidate CP3 star KIC 6128830. A detailed abundance analysis based on newly-acquired high-resolution spectra was performed, which confirms that the star's abundance pattern is fully consistent with its proposed classification. Photometric variability was investigated using four years of archival Kepler data. In agreement with results from the literature, we have identified a single significant and independent frequency $f_1$=0.2065424 d$^{-1}$ with a peak-to-peak amplitude of $\sim$3.4 mmag and harmonic frequencies up to $5f_1$. Drawing on the predictions of state-of-the-art pulsation models and information on evolutionary status, we discuss the origin of the observed light changes. Our calculations predict the occurrence of g-mode pulsations at the observed variability frequency. On the other hand, the strictly mono-periodic nature of the variability strongly suggests a rotational origin. While we prefer the rotational explanation, the present data leave some uncertainty.Comment: 13 pages, 13 figures, accepted for publication in MNRA

The incidence of cervical intraepithelial neoplasia in a population of pregnant women with an abnormal cytology

Objectives: To assess the incidence of cervical intraepithelial neoplasia — SIL and cervical cancer in a population of pregnant women with an abnormal cytology. Material and methods: In pregnant women with abnormal cytology results according to The Bethesda System, a verifying diagnostics was carried out, including colposcopy and cervical biopsy. Results: The most common histological and oncologic diagnosis in the whole study group of pregnant women were HGSIL changes, covering cervical intraepithelial neoplasia of medium and high grade — CIN 2 and CIN 3. Conclusions: HGSIL changes are the most common oncological pathology in a population of pregnant women with an abnormal cytology. Precise risk identification of HGSIL changes with the use of molecular tests can significantly reduce the number of surgical procedures in a population of pregnant patients with a cytological diagnosis of ASCUS and LSIL

Rola marki dyplomu w perspektywie niżu demograficznego w Polsce 2010-2020 (CPP RPS 65/2014)

Przedmiotem artykułu są zmiany w polskim szkolnictwie wyższym wynikające z umasowienia szkolnictwa wyższego, przeobrażeń struktury gospodarki w kierunku modelu postindustrialnego oraz liberalnych reform polskiego szkolnictwa wyższego. Celem analiz jest pokazanie, ze w warunkach rosnącej konkurencji coraz większe znaczenie będzie miała marka dyplomu uczelni. W Polsce marka dyplomu uczelni nie odgrywała dotąd znaczącej roli, ponieważ zaległości edukacyjne, a przede wszystkim koniunktura demograficzna zapewniały wystarczająco wysoki poziom popytu na usługi edukacyjne w szkolnictwie wyższym. Ten okres już minął i w nadchodzących latach rywalizacja o studentów będzie coraz większa, a marka dyplomu już zaczyna odgrywać decydującą rolę w tym, które uczelnie pozostaną na rynku edukacyjnym, a które będą musiały przejść głęboką restrukturyzację lub po prostu zniknąć z rynku

Successful treatment of postoperative, radiation-associated wound dehiscence around tracheostomy with negative pressure wound therapy.

We present case report of 62-year-old man who underwent total laryngectomy, bilateral neck dissection and radiotherapy due to laryngeal cancer. After 11 months he was reoperated because of a local recurrence. The second procedure was complicated with postoperative wound dehiscence in tracheostomy site which was successfully treated with negative pressure wound therapy. We indicate the difficulties and point technical solutions for negative pressure dressing around the airway

Luteolin triggers global changes in the microglial transcriptome leading to a unique anti-inflammatory and neuroprotective phenotype

<p>Abstract</p> <p>Background</p> <p>Luteolin, a plant derived flavonoid, exerts a variety of pharmacological activities and anti-oxidant properties associated with its capacity to scavenge oxygen and nitrogen species. Luteolin also shows potent anti-inflammatory activities by inhibiting nuclear factor kappa B (NFkB) signaling in immune cells. To better understand the immuno-modulatory effects of this important flavonoid, we performed a genome-wide expression analysis in pro-inflammatory challenged microglia treated with luteolin and conducted a phenotypic and functional characterization.</p> <p>Methods</p> <p>Resting and LPS-activated BV-2 microglia were treated with luteolin in various concentrations and mRNA levels of pro-inflammatory markers were determined. DNA microarray experiments and bioinformatic data mining were performed to capture global transcriptomic changes following luteolin stimulation of microglia. Extensive qRT-PCR analyses were carried out for an independent confirmation of newly identified luteolin-regulated transcripts. The activation state of luteolin-treated microglia was assessed by morphological characterization. Microglia-mediated neurotoxicity was assessed by quantifying secreted nitric oxide levels and apoptosis of 661W photoreceptors cultured in microglia-conditioned medium.</p> <p>Results</p> <p>Luteolin dose-dependently suppressed pro-inflammatory marker expression in LPS-activated microglia and triggered global changes in the microglial transcriptome with more than 50 differentially expressed transcripts. Pro-inflammatory and pro-apoptotic gene expression was effectively blocked by luteolin. In contrast, mRNA levels of genes related to anti-oxidant metabolism, phagocytic uptake, ramification, and chemotaxis were significantly induced. Luteolin treatment had a major effect on microglial morphology leading to ramification of formerly amoeboid cells associated with the formation of long filopodia. When co-incubated with luteolin, LPS-activated microglia showed strongly reduced NO secretion and significantly decreased neurotoxicity on 661W photoreceptor cultures.</p> <p>Conclusions</p> <p>Our findings confirm the inhibitory effects of luteolin on pro-inflammatory cytokine expression in microglia. Moreover, our transcriptomic data suggest that this flavonoid is a potent modulator of microglial activation and affects several signaling pathways leading to a unique phenotype with anti-inflammatory, anti-oxidative, and neuroprotective characteristics. With the identification of several novel luteolin-regulated genes, our findings provide a molecular basis to understand the versatile effects of luteolin on microglial homeostasis. The data also suggest that luteolin could be a promising candidate to develop immuno-modulatory and neuroprotective therapies for the treatment of neurodegenerative disorders.</p

Novel Technique for Treating Multiple Wounds with Negative Pressure Wound Therapy

Treatment of separate wounds on the same patient with one NPWT device may be challenging. We present novel, cost-effective technique for multiple wounds management

The use of NPWT in combination with silver dressing in diabetic foot syndrome – case report

oai:ojs.npwtj.com:article/5Patients with diabetes mellitus are at increased risk of angiopathy, neuropathy and infection compared with healthy individuals and that may lead to foot disorders. Treatment is difficult challenging and if it is not successful it often run to lower limbs amputations.We present case report of 63 years old man after amputation of big toe and part of metatarsus due to diabetic foot syndrome, successfully treated with negative pressure wound therapy in combination with silver dressing. The literature regarding this issue was also reviewed

A simple and low- cost technique for Closed Incision Negative-Pressure Therapy

Surgical site infection (SSI) makes patient care more expensive by prolonging antibiotic usage and hospital stay. Negative pressure wound therapy (NPWT) has been recently reported as a preventive strategy to avoid SSI. We present a simple and low-cost vacuum dressing that may improve surgical wound healing and prevent high-risk wounds from complications

Novel, self-made and cost-ective technique for closed-incision negative pressure wound therapy

Background: It has been suggested that applying the negative pressure wound therapy (NPWT) to a closedsurgical incision may hasten the healing of the incision and decrease the incidence of wound healing complications. The goal of this study is to present the new idea of a simple, self-made, low-cost wound vacuum dressing for closed-incision NPWT that may become an alternative to currently manufactured medicalindustry products.Method: We designed a simple dressing for closed-incision NPWT from gauze pads, polyurethane adhesive film, stoma paste, and a drain tube. Negative pressure was created using a standard 50 ml syringe connected to the drain. First, the dressing was applied to the wound model and on the healthy volunteer. Finally, the dressing was applied to 10 patients after low anterior rectal resection. The vacuum dressing was left in place for 3 days, then changed and placed once more for the next 3 days.Results: We did not observe any adverse effects associatedwith the dressing. All postoperative wounds healed properly. 18 out of 20 dressings were still air-tight 72h post-placement.Conclusions: This simple, self-made dressing for NPWT is safe and effective and may decrease the wound infection rate. However future studies are needed to confirm that hypothesis