Iron Hack - A symposium/hackathon focused on porphyrias, Friedreich's ataxia, and other rare iron-related diseases.

Background: Basic and clinical scientific research at the University of South Florida (USF) have intersected to support a multi-faceted approach around a common focus on rare iron-related diseases. We proposed a modified version of the National Center for Biotechnology Information's (NCBI) Hackathon-model to take full advantage of local expertise in building "Iron Hack", a rare disease-focused hackathon. As the collaborative, problem-solving nature of hackathons tends to attract participants of highly-diverse backgrounds, organizers facilitated a symposium on rare iron-related diseases, specifically porphyrias and Friedreich's ataxia, pitched at general audiences. Methods: The hackathon was structured to begin each day with presentations by expert clinicians, genetic counselors, researchers focused on molecular and cellular biology, public health/global health, genetics/genomics, computational biology, bioinformatics, biomolecular science, bioengineering, and computer science, as well as guest speakers from the American Porphyria Foundation (APF) and Friedreich's Ataxia Research Alliance (FARA) to inform participants as to the human impact of these diseases. Results: As a result of this hackathon, we developed resources that are relevant not only to these specific disease-models, but also to other rare diseases and general bioinformatics problems. Within two and a half days, "Iron Hack" participants successfully built collaborative projects to visualize data, build databases, improve rare disease diagnosis, and study rare-disease inheritance. Conclusions: The purpose of this manuscript is to demonstrate the utility of a hackathon model to generate prototypes of generalizable tools for a given disease and train clinicians and data scientists to interact more effectively

Embedded System Design of a Real-time Parking Guidance System

The primary objective of this work is to design a parking guidance system to reliably detect entering/exiting vehicles to a parking garage in a cost-efficient manner. Existing solutions (inductive loops, RFID based systems, and video image processors) at shopping malls, universities, airports etc., are expensive due to high installation and maintenance costs. There is a need for a parking guidance system that is reliable, accurate, and cost-effective. The proposed parking guidance system is designed to optimize the use of parking spaces and to reduce wait times. Based on a literature review we identify that the ultrasonic sensor is suitable to detect an entering/exiting vehicle. Initial experiments were performed to test the sensor using an Arduino based embedded system. Detection logic was then developed to identify a car after analyzing the initial test results. This logic was extended to trigger a camera to take an image of the vehicle for validation purposes. This system consists of Arduino, ultrasonic sensor, and a temperature sensor. It was installed and tested in Richard Beard Garage at the University of South Florida for five days. The test results of each trial are provided and average error for all the trials is calculated. The error cases occur due to golf carts, straddling cars on both entry/exit lanes, and people walking under the sensor. The average error of the system is 5.36% over five days (120 hrs). The estimated cost for one detector per lane is approximately $30