AKARI Far-Infrared Source Counts in the Lockman Hole

We report initial results of far-infrared observations of the Lockman hole with Far-Infrared Surveyor (FIS) onboard the AKARI infrared satellite. On the basis of slow scan observations of a 0.6 deg x 1.2 deg contiguous area, we obtained source number counts at 65, 90 and 140 um down to 77, 26 and 194 mJy (3 sigma), respectively. The counts at 65 and 140 um show good agreement with the Spitzer results. However, our 90 um counts are clearly lower than the predicted counts by recent evolutionary models that fit the Spitzer counts in all the MIPS bands. Our 90 um counts above 26 mJy account for about 7% of the cosmic background. These results provide strong constraints on the evolutionary scenario and suggest that the current models may require modifications.Comment: 25 pages, 8 figures, Publications of the Astronomical Society of Japan, in pres

Biological interaction of alginetin

Alginetin is the major product formed from pentoses and hexurionic acids. Alginetin is producted by cooking process of food including pection, a naturally-occurring polysacharride found in many plants. However, the biological interaction and toxicity of alginetin are not known at all. The aim of the present study was to investigate the cellular actions of alginetin on rat thymic lymphocytes. The effects of alginetin on the cell were examined using flow cytometry with fluorescent probes. Alginetin increased cellular content of non-protein thiols ([NPT]i) and elevated intracellular Zn2+ levels ([Zn2+]i). Chelation of intracellular Zn2+ reduced the effect of alginetin on [NPT]i, and chelation of external Zn2+ almost completely diminished alginetin-induced elevation of [Zn2+]i, indicating that alginetin treatment increased Zn2+ influx. Increased [NPT]i and [Zn2+]i levels in response to alginetin were positively correlated. Alginetin protected cells against oxidative stress induced by hydrogen peroxide and Ca2+ overload by calcium ionophore. It is considered that the increases in [NPT]i and [Zn2+]i are responsible for the cytoprotective activity of alginetin because NPT attenuates oxidative stress and Zn2+ competes with Ca2+. Alginetin may be produced during manufacturing of jam, which may provide additional health benefits of jam