380 research outputs found
Evaluation of activated protein C resistance in women undergoing in-vitro fertilization treatment
Evaluation of activated protein C resistance in women undergoing in-vitro fertilization treatment
Correlation between activated protein C resistance and the relative risk of venous thromboembolism in women using hormonal therapy
Correlation between activated protein C resistance and the relative risk of venous thromboembolism in women using hormonal therapy
Latest clinical recommendations on valproate use for migraine prophylaxis in women of childbearing age. Overview from European Medicines Agency and European Headache Federation
Migraine is a common and burdensome neurological condition which affects mainly female patients during their childbearing years. Valproate has been widely used for the prophylaxis of migraine attacks and is also included in the main European Guidelines. Previous (2014) European recommendations on limiting the use of valproate in women of childbearing age did not achieve their objective in terms of limiting the use of valproate in women of childbearing age and raising awareness regarding the hazardous effect of valproate to children exposed in utero. The teratogenic and foetotoxic effects of valproate are well documented, and more recent studies show that there is an even greater neurodevelopmental risk to children exposed to valproate in the womb. The latest 2018 European review from the European Medicines Agency, with the active participation of the European Headache Federation, concluded that not enough has been done to mitigate the risks associated with in utero exposure to valproate. The review called for more extensive restrictions to the conditions for prescribing, better public awareness, and a more effective education campaign in migrainous women
Data interpretation of the ETP-based APC resistance assay and the concept of nAPCsr10, an improved nAPCsr
Validation of an original ETP-based APC resistance assay for the evaluation of prothrombotic states
Data interpretation of the ETP-based APC resistance assay and the concept of nAPCsr10, an improved nAPCsr
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