167 research outputs found
Characterization of diamond-turned optics for SCALES
High-contrast imaging has been used to discover and characterize dozens of
exoplanets to date. The primary limiting performance factor for these
instruments is contrast, the ratio of exoplanet to host star brightness that an
instrument can successfully resolve. Contrast is largely determined by
wavefront error, consisting of uncorrected atmospheric turbulence and optical
aberrations downstream of AO correction. Single-point diamond turning allows
for high-precision optics to be manufactured for use in astronomical
instrumentation, presenting a cheaper and more versatile alternative to
conventional glass polishing. This work presents measurements of wavefront
error for diamond-turned aluminum optics in the Slicer Combined with an Array
of Lenslets for Exoplanet Spectroscopy (SCALES) instrument, a 2-5 micron
coronagraphic integral field spectrograph under construction for Keck
Observatory. Wavefront error measurements for these optics are used to simulate
SCALES' point spread function using physical optics propagation software poppy,
showing that SCALES' contrast performance is not limited by wavefront error
from internal instrument optics.Comment: Techniques and Instrumentation for Detection of Exoplanets X
Human genetics in troubled times and places
Abstract The development of human genetics world-wide during the twentieth century, especially across Europe, has occurred against a background of repeated catastrophes, including two world wars and the ideological problems and repression posed by Nazism and Communism. The published scientific literature gives few hints of these problems and there is a danger that they will be forgotten. The First World War was largely indiscriminate in its carnage, but World War 2 and the preceding years of fascism were associated with widespread migration, especially of Jewish workers expelled from Germany, and of their children, a number of whom would become major contributors to the post-war generation of human and medical geneticists in Britain and America. In Germany itself, eminent geneticists were also involved in the abuses carried out in the name of ‘eugenics’ and ‘race biology’. However, geneticists in America, Britain and the rest of Europe were largely responsible for the ideological foundations of these abuses. In the Soviet Union, geneticists and genetics itself became the object of persecution from the 1930s till as late as the mid 1960s, with an almost complete destruction of the field during this time; this extended also to Eastern Europe and China as part of the influence of Russian communism. Most recently, at the end of the twentieth century, China saw a renewal of government sponsored eugenics programmes, now mostly discarded. During the post-world war 2 decades, human genetics research benefited greatly from recognition of the genetic dangers posed by exposure to radiation, following the atomic bomb explosions in Japan, atmospheric testing and successive accidental nuclear disasters in Russia. Documenting and remembering these traumatic events, now largely forgotten among younger workers, is essential if we are to fully understand the history of human genetics and avoid the repetition of similar disasters in the future. The power of modern human genetic and genomic techniques now gives a greater potential for abuse as well as for beneficial use than has ever been seen in the past
Elucidation of Heterocumulene Activation by a Nucleophilic-at-Metal Iridium(I) Carbene
ChemInform Abstract: Organotransition Metal Modified Sugars. Part 10. Chromium Iminoglycosylidenes: Synthesis and Application to Photoinduced C-Glycosidation.
ChemInform Abstract: Reactions of Complex Ligands. Part 43. Optically Active Aminocarbene Complexes: Reagents for the Regiospecific and Diastereoselective Synthesis of γ-Lactams.
ChemInform Abstract: Reactions of Complex Ligands. Part 55. Fluorinated Hydroquinones via Annulation of Fluorovinylcarbene Complexes with Alkynes.
ChemInform Abstract: Fischer Carbene Complexes in Organic Synthesis: Metal-Assisted and Metal-Templated Reactions
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