An Investigation into the Accessibility of AP Calculus

This is a mixed methods ethnographic study conducted to determine what obstacles students face when approaching AP Calculus. I focused my study on home economics, peer pressure, ELL status and home support. Overall, I found that being a student who is ELL (hereafter defined as a student who was or currently is required to take ACCESS testing) had the most negative effect of the previously listed factors. Home economics and peer pressure were inconclusive or often had no effect. Finally, having a supportive home life in the form of parents who value education, encourage goal-setting, and set high expectations had a positive effect in accessing AP Calculus. These findings allow me to focus my future work to mitigate the negative and foster the positive influences

The Synthesis and Characterization of Binuclear Copper(I) Complexes as Models for Protein Active Sites

A series of coordinatively unsaturated copper(I) complexes of binucleating nitrogenous ligands have been examined as potential models for protein active sites. The first complex discussed is derived from the ligand N,N,N',N'-tetrakis(2-pyridylmethyl)-ethylenediamine (TPEN). The binuclear copper(I) complex Cu2(TPEN)2+ reversibly binds two equivalents of carbon monoxide, giving an adduct which displays a pair of CO stretching absorptions at 2097 and 2107 cm-1. Both Cu2(TPEN)(BF4)2 and its carbonyl adduct have been examined by single-crystal X-ray diffraction. Each copper atom of Cu2(TPEN)2+ is bound in a highly asymmetric environment, with an intramolecular copper-copper separation of 2.78Å. In the carbonyl adduct the metal-ligand bonds have rearranged, each copper has assumed a pseudotetrahedral geometry, and there is no longer any direct metal-metal interaction. Another complex, Cu2(CHXNpy)2+, has been prepared with a ligand analogous to TPEN, but with trans-1,2-cyclohexanediamine substituted for ethylenediamine. A second cyclohexanediamine-based ligand, CHXNbim, has been prepared which contains four benzimidazole groups rather than pyridine. Both Cu2(CHXNpy)2+ and Cu2(CHXNbim)2+ exhibit temperature dependent proton magnetic resonance spectra. The fact that fast exchange is observed only well above room temperature, in spite of the high lability of copper(I), is attributed to the sterically constrained nature of the ligands. Like Cu2(TPEN)2+, Cu2(CHXNpy)2+ forms a dicarbonyl adduct, but it is of lower stability. The benzimidazole complex Cu2(CHXNbim)2+ does not react with carbon monoxide and reacts only slowly with oxygen. Furthermore, unlike Cu2(TPEN)2+ and Cu2(CHXNpy)2+, Cu2(CHXNbim)2+ shows no tendency to disproportionate. This high stability is likely due to a combination of steric and electronic factors, which are discussed. Finally, a series of complexes having different xylylene "backbones" have been synthesized and examined. Each ligand contains four biologically relevant imidazole groups. All of the complexes react rapidly with carbon monoxide and oxygen (irreversibly in the latter case). In contrast with another known xylylene-based complex containing pyridine groups, the reaction with oxygen occurs without ligand hydroxylation. Factors which could contribute to the reactivity difference are discussed.</p

Sublingual Emphysema Following Alveoloplasty: A Case Report

Various cases of introduction of air into soft tissues have been reported in the dental literature. Here, we report a rare case of localized sublingual emphysema after alveoloplasty. There was no facial involvement. The patient responded to treatment and recovered uneventfully

Effect of membrane exposure on guided bone regeneration: A systematic review and metaâ analysis

AimsThis review aimed at investigating the effect of membrane exposure on guided bone regeneration (GBR) outcomes at periâ implant sites and edentulous ridges.Material and MethodsElectronic and manual literature searches were conducted by two independent reviewers using four databases, including MEDLINE, EMBASE, Web of Science, and Cochrane Central Register of Controlled Trials, for articles up to February 2017. Articles were included if they were human clinical trials or case series reporting outcomes of GBR procedures with and without membrane exposure. A randomâ effects metaâ analysis was conducted, and the weighted mean difference (WMD) between the two groups and 95% confidence interval (CI) were reported.ResultsOverall, eight articles were included in the quantitative analysis. The WMD of the horizontal bone gain at edentulous ridges was â 76.24% (95% CI = â 137.52% to â 14.97%, p = .01) between sites with membrane exposure and without exposure. In addition, the WMD of the dehiscence reduction at periâ implant sites was â 27.27% (95% CI of â 45.87% to â 8.68%, p = .004). Both analyses showed significantly favorable outcomes at the sites without membrane exposure.ConclusionBased on the findings of this study, membrane exposure after GBR procedures has a significant detrimental influence on the outcome of bone augmentation. For the edentulous ridges, the sites without membrane exposure achieved 74% more horizontal bone gain than the sites with exposure. For periâ implant dehiscence defects, the sites without membrane exposure had 27% more defect reduction than the sites with exposure.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142961/1/clr13121.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/142961/2/clr13121_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/142961/3/clr13121-sup-0003-checklist.pd

Weekly observations of online survey metadata obtained through home computer use allow for detection of changes in everyday cognition before transition to mild cognitive impairment

IntroductionSubtle changes in instrumental activities of daily living often accompany the onset of mild cognitive impairment (MCI) but are difficult to measure using conventional tests.MethodsWeekly online survey metadata metrics, annual neuropsychological tests, and an instrumental activity of daily living questionnaire were examined in 110 healthy older adults with intact cognition (mean age = 85 years) followed up for up to 3.6 years; 29 transitioned to MCI during study follow‐up.ResultsIn the baseline period, incident MCI participants completed their weekly surveys 1.4 hours later in the day than stable cognitively intact participants, P = .03, d = 0.47. Significant associations were found between earlier survey start time of day and higher memory (r = −0.34; P < .001) and visuospatial test scores (r = −0.37; P < .0001). Longitudinally, incident MCI participants showed an increase in survey completion time by 3 seconds per month for more than the year before diagnosis compared with stable cognitively intact participants (β = 0.12, SE = 0.04, t = 2.8; P = .006).DiscussionWeekly online survey metadata allowed for detection of changes in everyday cognition before transition to MCI.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/152601/1/alzjjalz201707756.pd

P3‐164: Less daily computer use is related to smaller hippocampal volumes in dementia‐free elderly

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/152632/1/alzjjalz2015061535.pd

Information and communication technology solutions for outdoor navigation in dementia

INTRODUCTION: Information and communication technology (ICT) is potentially mature enough to empower outdoor and social activities in dementia. However, actual ICT-based devices have limited functionality and impact, mainly limited to safety. What is an ideal operational framework to enhance this field to support outdoor and social activities? METHODS: Review of literature and cross-disciplinary expert discussion. RESULTS: A situation-aware ICT requires a flexible fine-tuning by stakeholders of system usability and complexity of function, and of user safety and autonomy. It should operate by artificial intelligence/machine learning and should reflect harmonized stakeholder values, social context, and user residual cognitive functions. ICT services should be proposed at the prodromal stage of dementia and should be carefully validated within the life space of users in terms of quality of life, social activities, and costs. DISCUSSION: The operational framework has the potential to produce ICT and services with high clinical impact but requires substantial investment

Compton Scattering by Nuclei

The concept of Compton scattering by even-even nuclei from giant-resonance to nucleon-resonance energies and the status of experimental and theoretical researches in this field are outlined. Nuclear Compton scattering in the giant-resonance energy-region provides information on the dynamical properties of the in-medium mass of the nucleon. The electromagnetic polarizabilities of the nucleon in the nuclear medium can be extracted from nuclear Compton scattering data obtained in the quasi-deuteron energy-region. Recent results are presented for two-body effects due to the mesonic seagull amplitude and due to the excitation of nucleon internal degrees of freedom accompanied by meson exchanges. Due to these studies the in-medium electromagnetic polarizabilities are by now well understood, whereas the understanding of nuclear Compton scattering in the Delta-resonance range is only at the beginning. Phenomenological methods how to include retardation effects in the scattering amplitude are discussed and compared with model predictions.Comment: 146 pages, 37 figures, submitted to Phys. Report

Preschool Behavioral and Social-Cognitive Problems as Predictors of (Pre)adolescent Disruptive Behavior

This article describes preschool social understanding and difficult behaviors (hot temper, disobedience, bossiness and bullying) as predictors of oppositional defiant disorder (ODD) and aggressive conduct disorder (ACD) in a Dutch population sample of (pre)adolescents (N = 1943), measured at age 10–12 and at age 13–15. ODD and ACD were assessed by the Child Behavior Checklist and the Youth Self-Report, preschool behavior was evaluated by the parental questionnaire ‹How was your child as a preschooler? (age 4–5)’. Adjusted for each other, all difficult preschool behaviors except bullying were associated with adolescent ODD, while only bullying significantly predicted adolescent ACD. Furthermore, the results suggest a qualitative difference between ODD and ACD in terms of the social component of the disorders: poor preschool social understanding was associated with the development of ACD but not of ODD; and poor social understanding interacted with difficult preschool behaviors to predict later ACD but not ODD. The associations did not differ between boys and girls, and were roughly similar for preadolescent (age 10–12) and early adolescent (age 13–15) outcomes. The finding that poor social understanding was implicated in the development of ACD but not in the development of ODD may help to demarcate the individuality of each disorder and offer leads for (differential) treatment strategies