12 research outputs found

    LE COMPLEXE 'TONOFILAMENT-DESMOSOME' NORMAL ET PATHOLOGIQUE

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    SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe

    Fixed drug eruption: Ultrastructural study of dyskeratotic cells

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    SCOPUS: ar.jFLWNAinfo:eu-repo/semantics/publishe

    Graft versus host reaction: an ultrastructural study

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    Graft versus host reaction (GvH) following leukocytic transfusions occurred in a 34-year-old man with a generalized lymphosarcoma. Histologic and ultrastructural studies were performed, with special reference to dyskeratotic cells scattered in the epidermis. These cells are usually considered to be a constant and important feature of GvH reaction. Dense aggregation of tonofilaments, including cytoplasmic organelles and loss of desmosomes, were seen in dyskeratotic cells. Several intracellular desmosomes with tonofilaments bound to their attachment plaque were observed. Some of these cells were able to reach the horny layer; some others were phagocytosed by neighboring keratinocytes. These cells could be the result of a toxic damage to the epidermis, provoked by the immunologic phenomenon implicated in GvH reaction. Later in the clinical course, bullae formations occurred, showing some features of toxic epidermal necrolysis (TEN), as well as features of GvH reaction.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

    Ichtyose linéaire circonflexe de comel: traitement par ro 10-9359. Étude en microscopie électronique

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    The authors show the noteworthy efficacy of the aromatic retinoid Ro 10-9359 in the treatment of ichthyosis linearis circumflexa. The initial dose was 1 mg/kg daily; later on, the maintenance dose was 0.3 mg/kg daily. Ultrastructurally, transitional cells were observed between the granular and the horny layer. After treatment, large perinuclear pseudovacuoles appeared, as well as numerous microvilli.SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe

    Collodion baby skin. Ultrastructural and autoradiographic study

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    SCOPUS: ar.jFLWNAinfo:eu-repo/semantics/publishe

    SYPHILIS SECONDAIRE ACTIVE ET PARALYSIE FACIALE PERIPHERIQUE

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    SCOPUS: ar.jinfo:eu-repo/semantics/publishe

    Staphylococcal scalded skin syndrome in an adult

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    The staphylococcal form of toxic epidermal necrolysis or staphylococcal scalded skin syndrome (SSSS) is exceptionally seen in an adult patient. We report a case of SSSS in a 21-year-old male who suffered from a fulminant pneumopathia due to a phage group II Staphylococcus aureus. The onset of that clinical picture in an adult patient is unusual and could be due to a deficient immunity, as previous case reports have emphasized. Unfortunately, the sudden death of our patient did not allow us to investigate his immunological defences. © 1975 S. Karger AG, Basel.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

    Pemphigus superficiel apparu lors du traitement d'une polyarthrite rhumatoïde par D-pénicillamine et piroxicam (Feldène).

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    The authors report a new case of induced pemphigus: a 64-year-old man has had rheumatoid arthritis for 10 years. When he developed his pemphigus, he had been taking D-penicillamine and piroxicam for about 8 months. He needed high doses of prednisolone associated with azathioprine to clear his eruption. The case had a fatal outcome.Case ReportsEnglish AbstractJournal ArticleSCOPUS: ar.jinfo:eu-repo/semantics/publishe
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