1,945 research outputs found

    A Prickly Subject: Apoptotic Regulation by Hedgehog Morphogens

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    Do LGBTQIA Rowan students matter? Marginality and mattering in Rowan University\u27s LGBTQIA undergraduate population

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    This study explores feelings of marginality and mattering as defined by Schlossberg (1989) in LGBTQIA undergraduate students at Rowan University. The study used a modified version of the College Mattering Inventory (Tovar, Simon, and Lee, distributed via email to students utilizing the university\u27s LGBTQIA Center. The study provided an opportunity for LGBTQIA undergraduate students to give feedback regarding their experiences at Rowan. A total of 39 students responded to the survey. The study found that LGBTQIA undergraduate students at Rowan University are experiencing feelings of mattering and marginality simultaneously. These students feel that they matter as students, and that they matter as LGBTQIA individuals, but there is dissonance between these identities that is creating feelings of isolation, loneliness, invisibility, and marginality. Overall, the LGBTQIA undergraduate population is struggling as a marginalized group, but is having some positive experiences indicative of feelings of mattering as well

    Is Honey, as Adjunctive Therapy, Effective in Alleviating Nasal Allergy Symptoms?

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    OBJECTIVE: The objective of this selective EBM review is to determine whether honey used as adjunctive therapy is effective in alleviating nasal allergy symptoms. STUDY DESIGN: This is a systematic review of three randomized controlled trials published between 2010-2013, all in the English language. DATA SOURCES: Three randomized controlled trials, which studied the effects of honey used as adjunctive therapy for the relief of nasal allergy symptoms, these were obtained using PubMed. OUTCOMES MEASURED: The outcome of each study was a patient reported decrease in the number of days and the severity of nasal allergy symptoms including: sneezing, itching, nasal blockage, and rhinorrhea. These outcomes were measured via daily diary entries, questionnaires regarding symptom severity and need for medication, Sino-Nasal Outcome Test (SNOT-22) questionnaire, and a 7-point visual analog symptom severity scale. RESULTS: All three RCTs determined that nasal allergy symptoms were decreased a statistically significant amount, as defined by a p-value \u3c0.05, with the addition of honey in subject’s daily medication regimen. This was compared to control, which consisted of patients taking only their normal daily medication and no honey products or a visually and taste matched placebo. CONCLUSIONS: The results of this systematic review have demonstrated that honey is effective in alleviating nasal allergy symptoms in numerous mediums including nasal spray as well as oral intake when produced in the geographic area in which the patient population resides. Whilst positive and promising results were obtained from these studies, additional research with larger patient populations, standardized honey product, and increased time frame of study is required to ascertain how beneficial honey truly is and if these benefits last

    Radicals in carbonaceous residue deposited on mordenite from methanol

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    It is shown that control of the degree of coking can lead to the observation of hyperfine structures in the carbonaceous residues deposited from methanol over mordenite (H-MOR) at temperatures relevant to the conversion of methanol to hydrocarbons. EPR measurements of the catalyst samples at various times on stream have been recorded, with a rich hyperfine splitting pattern observed in the early stages of the reaction. Interpretation of the EPR data with the aid of density functional theoretical calculations has afforded the first definitive assignment of the radical cations formed in high temperature coke. The results detail a shortlist of six species: 2,3/2,6/2,7-dimethylnaphthalenium, 2,3,6-trimethylnaphthalenium, 2,3,6,7-tetramethylnaphthalenium, and anthracenium radical cations whose proton hyperfine splitting profiles match the experimental spectra; 2,3,6,7-tetramethylnaphthalenium showed the best agreement. The observation of these particular isomers of polymethylnaphthalene suggest the formation of more highly branched polyaromatic species is less likely within the confines of the H-MOR 12-membered ring channel. These radicals formed when the catalyst is active may constitute key intermediates in the conversion of methanol to light olefins

    The separation of the eastern and western churches

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    Thesis (M.A.)--Boston University, 1934. This item was digitized by the Internet Archive

    A Practical Framework to Study Low-Power Scheduling Algorithms on Real-Time and Embedded Systems

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    With the advanced technology used to design VLSI (Very Large Scale Integration) circuits, low-power and energy-efficiency have played important roles for hardware and software implementation. Real-time scheduling is one of the fields that has attracted extensive attention to design low-power, embedded/real-time systems. The dynamic voltage scaling (DVS) and CPU shut-down are the two most popular techniques used to design the algorithms. In this paper, we firstly review the fundamental advances in the research of energy-efficient, real-time scheduling. Then, a unified framework with a real Intel PXA255 Xscale processor, namely real-energy, is designed, which can be used to measure the real performance of the algorithms. We conduct a case study to evaluate several classical algorithms by using the framework. The energy efficiency and the quantitative difference in their performance, as well as the practical issues found in the implementation of these algorithms are discussed. Our experiments show a gap between the theoretical and real results. Our framework not only gives researchers a tool to evaluate their system designs, but also helps them to bridge this gap in their future works

    Lifestyle diseases and cardiovascular risk factors are interrelated to deficiencies of major substrates in ATP synthesis

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    Recent studies on diabetes and metabolic syndrome indicate a common disturbance of inorganic phosphate (Pi) metabolism. Pi is an important substrate in the formation of adenosine triphosphate (ATP), and many lifestyle diseases and cardiovascular risk factors similarly show deficiencies in either 1 or 2 major components of ATP synthesis. Age, male gender, hypertension, obesity, hypertriglyceridemia, metabolic syndrome, and diabetes mellitus are all associated with hypophosphatemia. In addition, tobacco smoking, hyperchylomicronemia, hypertension, and diabetes may involve defects in tissue oxygen delivery. Hypophosphatemia may lead to a critical decrease in intracellular Pi and to mitochondrial dysfunction, which might be counter-acted by the pharmacological use of fructose 1,6-diphosphate

    Disturbance of inorganic phosphate metabolism in diabetes mellitus: clinical manifestations of phosphorus-depletion syndrome during recovery from diabetic ketoacidosis

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    The acute effects of intracellular phosphate depletion and hypophosphatemia on organs and tissues in and during recovery from diabetic ketoacidosis (DKA) have been reviewed. When insufficient phosphate and/or oxygen are available for high energy phosphate synthesis, cell homeostasis cannot be maintained and cell integrity may be impaired. The clinical consequences are recognized as occasional cause of morbidity and mortality. Although phosphate repletion has not been routinely recommended in the treatment of DKA, physicians should be aware of these clinical conditions and phosphate repletion in such situations should be considered

    Disturbance of inorganic phosphate metabolism in diabetes mellitus: temporary therapeutic intervention trials

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    A paradoxical metabolic imbalance in inorganic phosphate occurs from the early onset of diabetes and may lead to a reduction of high energy phosphates and tissue hypoxia. These changes take place in the cells and tissues in which the entry of glucose is not controlled by insulin, and particularly in poorly regulated diabetes patients in whom long-term vascular complications are more likely to occur. Several therapeutic intervention trials have been carried out, including assessment of optimal glucose regulation, the effect of dietary inclusion of calcium diphosphate and pharmaceutical intake of etidronate disodium (EHDP), but none of these modalities wholly overcome the problem. The potential therapeutic application of fructose-1, 6-diphosphate, however, which also acts as human bioenergy, holds a great deal of promise as an efficacious and well-tolerated therapeutic regimen
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