Six Pathways to Enduring Results: Lessons from Spend-Down Foundations

Fifty years ago, only 5 percent of the total assets of America's largest 50 foundations were held by spend-downs, compared to 24 percent in 2010. Spend-downs are even more influential when measured as a percent of giving, since they disburse money at a higher annual rate than foundations that aim to last forever. In 2010, 31 percent of giving from the largest foundations came from spend-downs (a figure that reflects the outsized effect of Bill and Melinda Gates and Warren Buffett)

If You’ve Got It, Flaunt It!: Refocusing a Collection with No Connection

Many libraries have a unique collection within their space that holds value and importance but has lost its connection to the college curriculum and the undergraduate research on campus. These collections may have had different people overseeing them over time or had changes in funding. They might have been created without thinking about the big picture. The paper examines one college library’s experience of turning an underused and unfocused collection into a vibrant and relevant part of the library through collaboration with key constituents in the academic and local community and staying true to the mission and vision

The Tiger Foundation: A Profile in Engaged Philanthropy

Tiger Management was one of the most successful hedge funds of the 1990s. But founder Julian Robertson also wanted to foster a lifelong commitment to giving back among his staff. So in 1990, he created Tiger Foundation with a unique dual mission: To provide financial support to the top nonprofit organizations serving New York City's neediest families;To encourage active, informed philanthropy among the staff at the firm The Foundation marries the rigor and analytics of the investment process to grantor/grantee relationships. Individual trustees not only pore over analytics compiled by Foundation staff, but also meet their grantees face to face and champion them at trustee meetings.The result is nothing short of transformative -- for the organizations Tiger funds and for the decision makers

Weathering the Storm: Riding the Waves of an Evolving Profession in Turbulent Times

Librarians are no strangers to re-envisioning themselves. From the closed stacks and “guardians of information” era, to the open learning commons and information desk model, we have evolved as needed to better serve the needs of our communities. As we adapt to changes in technology, information needs, and learning models, we aim to remain viable, maintain sustainable practices, and still feel invigorated by our profession. This can be a struggle given the need to continue some traditional aspects of librarianship, while trying to incorporate innovative information literacy practices, dynamic collection development, and cross-campus collaboration.. Non-library faculty and campus administration often have an “ideal library” in mind that doesn’t necessarily fit with the changing professional identity of some academic librarians. Library faculty often feel a sense of double-consciousness as they are asked to support other faculty, but also engage in their own teaching and scholarship. Additionally, as budgets shrink, it can be difficult to remain optimistic about the viability of the library. However, uncertain budgets, and a rapidly evolving environment has given one library a sense of opportunity and a desire to proactively change their identity on campus. This panel focuses on how library faculty at one public liberal arts institution are working toward reframing themselves, their work, and their library. They will discuss the challenges and benefits of reframing information literacy sessions, and creating and teaching in an Information Studies minor. They will highlight the changes in workload as they looked to new ways of working with campus faculty on information literacy, collection development, and liaison work, and became involved in campus initiatives beyond the library. They will address the challenges and opportunities that arise from using students to staff the library’s information desk and teach database demonstrations in place of librarians. Finally, they will discuss how their identity is evolving to incorporate new Framework principles and what they envision for the future of their library. Attendees of this session will leave with an understanding of the benefits and challenges of changing public service models, liaison roles, and instruction and reference work for library faculty

A combination of norethindrone acetate and leuprolide acetate blocks the gonadotrophin-releasing hormone agonistic response and minimizes cyst formation during ovarian stimulation

A protocol utilizing both leuprolide acetate (LA) and norethindrone acetate (NETA) in subjects undergoing ovarian suppression prior to follicle aspiration proved more effective than LA alone in reducing the incidence of ovarian cyst formation without affecting clinical outcome. Patients (n = 105) undergoing ovarian stimulation followed by follicle aspiration and in-vitro fertilization (IVF) were prospectively randomized and studied. Study measures included ovarian suppression days, days of human meno-pausal gonadotrophin (HMG) stimulation, serum oestradiol concentrations, number of cycles developing de novo cysts (> 15 mm), number of induced flare responses (day 8 oestradiol 5=50 pg/ml), number of office visits, total dose exogenous gonadotrophins, number oocytes retrieved, and clinical pregnancy and delivery rates per retrieval. Patients undergoing FVF received either LA alone (n = 58; controls) or LA and NETA (n = 47; study group) for the first 8 days of their cycle. Results comparing NETA/LA versus LA demonstrated: serum oestradiol 20.7 ± 3.9 versus 573 ± 9.4 pg/ml respectively on day 8 of ovarian suppression (P 15 mm compared to 15 (25.9%) controls (P < 0.01). No differences were observed for days of stimulation, peak oestradiol attained, total dosage of exogenous gonadotrophins, or number of aspirated oocytes. Neither were there differences in the clinical pregnancy (26.8 versus 22.6%) nor in delivery rates (19.5 versus 20.8%). We conclude that the addition of NETA to LA enhances ovarian suppression and lessens ovarian cyst formation, thereby significantly decreasing the overall cost per cycle

Epithelial atypia in biopsies performed for microcalcifications. Practical considerations about 2,833 serially sectioned surgical biopsies with a long follow-up

This study analyzes the occurrence of epithelial atypia in 2,833 serially sectioned surgical breast biopsies (SB) performed for microcalcifications (median number of blocks per SB:26) and the occurrence of subsequent cancer after an initial diagnosis of epithelial atypia (median follow-up 160 months). Epithelial atypia (flat epithelial atypia, atypical ductal hyperplasia, and lobular neoplasia) were found in 971 SB, with and without a concomitant cancer in 301 (31%) and 670 (69%) SB, respectively. Thus, isolated epithelial atypia were found in 670 out of the 2,833 SB (23%). Concomitant cancers corresponded to ductal carcinomas in situ and micro-invasive (77%), invasive ductal carcinomas not otherwise specified (15%), invasive lobular carcinomas (4%), and tubular carcinomas (4%). Fifteen out of the 443 patients with isolated epithelial atypia developed a subsequent ipsilateral (n = 14) and contralateral (n = 1) invasive cancer. The high slide rating might explain the high percentages of epithelial atypia and concomitant cancers and the low percentage of subsequent cancer after a diagnosis of epithelial atypia as a single lesion. Epithelial atypia could be more a risk marker of concomitant than subsequent cancer