1,680 research outputs found

    Vortex Fluctuations in the Critical Casimir Effect of Superfluid and Superconducting Films

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    Vortex-loop renormalization techniques are used to calculate the magnitude of the critical Casimir forces in superfluid films. The force is found to become appreciable when size of the thermal vortex loops is comparable to the film thickness, and the results for T < Tc are found to match very well with perturbative renormalization theories that have only been carried out for T > Tc. When applied to a high-Tc superconducting film connected to a bulk sample, the Casimir force causes a voltage difference to appear between the film and bulk, and estimates show that this may be readily measurable.Comment: 4 pages, 5 figures, Revtex 4, typo correctio

    Critical Casimir force in 4^4He films: confirmation of finite-size scaling

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    We present new capacitance measurements of critical Casimir force-induced thinning of 4^4He films near the superfluid/normal transition, focused on the region below TλT_{\lambda} where the effect is the greatest. 4^4He films of 238, 285, and 340 \AA thickness are adsorbed on N-doped silicon substrates with roughness 8A˚\approx 8 {\AA}. The Casimir force scaling function ϑ\vartheta , deduced from the thinning of these three films, collapses onto a single universal curve, attaining a minimum ϑ=1.30±0.03\vartheta = -1.30 \pm 0.03 at x=td1/ν=9.7±0.8A˚1/νx=td^{1/\nu}=-9.7\pm 0.8 {\AA}^{1/\nu}. The collapse confirms the finite-size scaling origin of the dip in the film thickness. Separately, we also confirm the presence down to 2.13K2.13 K of the Goldstone/surface fluctuation force, which makes the superfluid film 2A˚\sim 2 {\AA} thinner than the normal film.Comment: 4 pages, 3 figures, submitted to PR

    Distributed Approximation of Minimum Routing Cost Trees

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    We study the NP-hard problem of approximating a Minimum Routing Cost Spanning Tree in the message passing model with limited bandwidth (CONGEST model). In this problem one tries to find a spanning tree of a graph GG over nn nodes that minimizes the sum of distances between all pairs of nodes. In the considered model every node can transmit a different (but short) message to each of its neighbors in each synchronous round. We provide a randomized (2+ϵ)(2+\epsilon)-approximation with runtime O(D+lognϵ)O(D+\frac{\log n}{\epsilon}) for unweighted graphs. Here, DD is the diameter of GG. This improves over both, the (expected) approximation factor O(logn)O(\log n) and the runtime O(Dlog2n)O(D\log^2 n) of the best previously known algorithm. Due to stating our results in a very general way, we also derive an (optimal) runtime of O(D)O(D) when considering O(logn)O(\log n)-approximations as done by the best previously known algorithm. In addition we derive a deterministic 22-approximation

    Polymer lattices as mechanically tunable 3-dimensional photonic crystals operating in the infrared

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    Broadly tunable photonic crystals in the near- to mid-infrared region could find use in spectroscopy, non-invasive medical diagnosis, chemical and biological sensing, and military applications, but so far have not been widely realized. We report the fabrication and characterization of three-dimensional tunable photonic crystals composed of polymer nanolattices with an octahedron unit-cell geometry. These photonic crystals exhibit a strong peak in reflection in the mid-infrared that shifts substantially and reversibly with application of compressive uniaxial strain. A strain of ∼40% results in a 2.2 μm wavelength shift in the pseudo-stop band, from 7.3 μm for the as-fabricated nanolattice to 5.1 μm when strained. We found a linear relationship between the overall compressive strain in the photonic crystal and the resulting stopband shift, with a ∼50 nm blueshift in the reflection peak position per percent increase in strain. These results suggest that architected nanolattices can serve as efficient three-dimensional mechanically tunable photonic crystals, providing a foundation for new opto-mechanical components and devices across infrared and possibly visible frequencies

    Does insurance fraud in automobile theft insurance fluctuate with the business cycle?

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    [[abstract]]Financial institutions face various cyclical risks, but very few studies have analyzed the cyclicality of operational risk. External fraud is an important operational risk faced by insurers. In this research, we analyze the empirical relationship between insurance fraud and business cycle and we concentrate our study on two insurance contracts that may create an incentive to defraud. We find that residual insurance fraud exists both in the contract with replacement cost endorsement and the contract with no-deductible endorsement in the Taiwan automobile theft insurance market. These results are consistent with previous literature on the relationship between fraud activity and non-optimal insurance contracting. We also show that the severity of insurance fraud is countercyclical. Fraud is stimulated during periods of recession and mitigated during periods of expansion. Although this last result seems intuitive, our contribution is the first to measure its significance.[[notice]]補正完畢[[incitationindex]]SSCI[[booktype]]紙本[[booktype]]電子

    Remodeling Protein Interfaces to Regulate Recognition

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    Managing healthcare budgets in times of austerity: the role of program budgeting and marginal analysis

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    Given limited resources, priority setting or choice making will remain a reality at all levels of publicly funded healthcare across countries for many years to come. The pressures may well be even more acute as the impact of the economic crisis of 2008 continues to play out but, even as economies begin to turn around, resources within healthcare will be limited, thus some form of rationing will be required. Over the last few decades, research on healthcare priority setting has focused on methods of implementation as well as on the development of approaches related to fairness and legitimacy and on more technical aspects of decision making including the use of multi-criteria decision analysis. Recently, research has led to better understanding of evaluating priority setting activity including defining ‘success’ and articulating key elements for high performance. This body of research, however, often goes untapped by those charged with making challenging decisions and as such, in line with prevailing public sector incentives, decisions are often reliant on historical allocation patterns and/or political negotiation. These archaic and ineffective approaches not only lead to poor decisions in terms of value for money but further do not reflect basic ethical conditions that can lead to fairness in the decision-making process. The purpose of this paper is to outline a comprehensive approach to priority setting and resource allocation that has been used in different contexts across countries. This will provide decision makers with a single point of access for a basic understanding of relevant tools when faced with having to make difficult decisions about what healthcare services to fund and what not to fund. The paper also addresses several key issues related to priority setting including how health technology assessments can be used, how performance can be improved at a practical level, and what ongoing resource management practice should look like. In terms of future research, one of the most important areas of priority setting that needs further attention is how best to engage public members

    Bacterial toxin-triggered release of antibiotics from capsosomes protects a fly model from lethal methicillin-resistant Staphylococcus aureus (MRSA) infection

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    Antibiotic resistance is a severe global health threat and hence demands rapid action to develop novel therapies, including microscale drug delivery systems. Herein, a hierarchical microparticle system is developed to achieve bacteria-activated single- and dual-antibiotic drug delivery for preventing methicillin-resistant Staphylococcus aureus (MRSA) bacterial infections. The designed system is based on a capsosome structure, which consists of a mesoporous silica microparticle coated in alternating layers of oppositely charged polymers and antibiotic-loaded liposomes. The capsosomes are engineered and shown to release their drug payloads in the presence of MRSA toxins controlled by the Agr quorum sensing system. MRSA-activated single drug delivery of vancomycin and synergistic dual delivery of vancomycin together with an antibacterial peptide successfully kills MRSA in vitro. The capability of capsosomes to selectively deliver their cargo in the presence of bacteria, producing a bactericidal effect to protect the host organism, is confirmed in vivo using a Drosophila melanogaster MRSA infection model. Thus, the capsosomes serve as a versatile multidrug, subcompartmentalized microparticle system for preventing antibiotic-resistant bacterial infections, with potential applications to protect wounds or medical device implants from infections

    Faraday rotation spectra of bismuth-substituted ferrite garnet films with in-plane magnetization

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    Single crystalline films of bismuth-substituted ferrite garnets have been synthesized by the liquid phase epitaxy method where GGG substrates are dipped into the flux. The growth parameters are controlled to obtain films with in-plane magnetization and virtually no domain activity, which makes them excellently suited for magnetooptic imaging. The Faraday rotation spectra were measured across the visible range of wavelengths. To interprete the spectra we present a simple model based on the existence of two optical transitions of diamagnetic character, one tetrahedral and one octahedral. We find excellent agreement between the model and our experimental results for photon energies between 1.77 and 2.53 eV, corresponding to wavelengths between 700 and 490 nm. It is shown that the Faraday rotation changes significantly with the amount of substituted gallium and bismuth. Furthermore, the experimental results suggest that the magnetooptic response changes linearly with the bismuth substitution.Comment: 15 pages, 6 figures, published in Phys. Rev.
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