The Influence Of User Interaction And Participation In Social Media On The Consumption Intention Of Niche Products

The potential of social media in helping businesses generate commercial values has attracted significant attention from researchers and practitioners alike in recent years. An important characteristic differentiating social media from traditional media is the central role of user interaction and participation in generating content that makes the platform sustainable and potentially profitable. It has been noted that social media may be particularly apt in promoting the sales of niche products, due to the tendency of consumers to generate reviews and discuss about such products that raise awareness about them. In this study, we build on and extend the extant literature to investigate how patterns of social interaction among the consumers in discussing about a niche product influence the overall level of participation, which in turn enhances consumption intention of the product. Through analyzing data from a social media site that allows consumers to comment on and discuss about books of philosophical genre (a niche product type), we show that the level of user participation can indeed have a significant positive effect on consumption intention. Furthermore, inclusiveness and betweenness centralization structures may enhance the participation level, but out-degree centralization has a detrimental effect. Implications for research and practice are discussed

Circulating MicroRNAs: Potential Biomarkers for Cancer

Cancer is the leading cause of death in the world. Development of minimally invasive biomarkers for early detection of cancer is urgently needed to reduce high morbidity and mortality associated with malignancy. MicroRNAs (miRNAs) are small regulatory RNAs that modulate the activity of specific mRNA targets and play important roles in a wide range of physiologic and pathologic processes. Recently, miRNAs were found to be dysregulated in a variety of diseases including cancer. Emerging evidence suggests that miRNAs are involved in tumor initiation and progression. Together, the different expression profiles of miRNAs in cancer, and the stability of circulating miRNAs, make them new potentially clinical biomarkers for cancer diagnosis, classification, therapeutic decisions, and prognosis