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    InteRhemispheric differences in clinical outcome after intravenous thrombolysis

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    Π§ΠΎΠ²Π΅ΡˆΠΊΠΈΡΡ‚ мозък сС Ρ…Π°Ρ€Π°ΠΊΡ‚Π΅Ρ€ΠΈΠ·ΠΈΡ€Π° с Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΎΠ½Π°Π»Π½Π° асимСтрия, Π²ΠΊΠ»ΡŽΡ‡Π²Π°Ρ‰Π° мСТдухСмисфСрни, ΠΊΠΎΡ€ΠΎΠ²ΠΈ ΠΈ ΠΏΠΎΠ΄ΠΊΠΎΡ€ΠΎΠ²ΠΈ взаимодСйствия. ΠŸΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈΡ‚Π΅ с ИМИ Π² лява хСмисфСра ΠΈ ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½ΠΎ Ρ‚Ρ€ΠΎΠΌΠ±ΠΎΠ»ΠΈΡ‚ΠΈΡ‡Π½ΠΎ Π»Π΅Ρ‡Π΅Π½ΠΈΠ΅ (Π’Π›) ΠΈΠΌΠ°Ρ‚ Π΄Π²Π° ΠΏΡŠΡ‚ΠΈ ΠΏΠΎ-голяма вСроятност Π·Π° благоприятСн ΠΊΠ»ΠΈΠ½ΠΈΡ‡Π΅Π½ ΠΈΠ·Ρ…ΠΎΠ΄ Π½Π° трСтия мСсСц сравнСно с дяснохСмисфСрнитС ΠΈΠ½Ρ„Π°Ρ€ΠΊΡ‚ΠΈ. ЖСнският ΠΏΠΎΠ» ΠΈ лСвостранната локализация са ΠΏΡ€Π΅Π΄ΠΈΠΊΡ‚ΠΎΡ€ΠΈ Π½Π° Π·Π½Π°Ρ‡ΠΈΠΌΠΎ ΠΏΠΎΠ΄ΠΎΠ±Ρ€Π΅Π½ΠΈΠ΅ Π½Π° нСврологичния Π΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚ Π½Π° 24-я час слСд Π’Π›. ΠžΡ‚ Π΄Ρ€ΡƒΠ³Π° страна асоциацията Π½Π° мъТки ΠΏΠΎΠ» ΠΈ дяснохСмисфСрна локализация Π½Π° инсулта Π΅ ΡΠ²ΡŠΡ€Π·Π°Π½Π° с ΠΏΠΎ-голяма вСроятност Π·Π° благоприятСн ΠΊΠ»ΠΈΠ½ΠΈΡ‡Π΅Π½ ΠΈΠ·Ρ…ΠΎΠ΄ ΠΎΡ‚ΠΊΠΎΠ»ΠΊΠΎΡ‚ΠΎ ΠΏΡ€ΠΈ ΠΆΠ΅Π½ΠΈΡ‚Π΅ със ΡΡŠΡ‰Π°Ρ‚Π° локализация. Π‘ΡŠΡ‰ΠΎ Ρ‚Π°ΠΊΠ° дяснохСмисфСрната локализация Π½Π° инсулта ΠΏΡ€ΠΈ ΠΌΡŠΠΆΠ΅Ρ‚Π΅ сС ΡΠ²ΡŠΡ€Π·Π²Π° с ΠΏΠΎ-Π΄ΠΎΠ±ΡŠΡ€ ΠΈΠ·Ρ…ΠΎΠ΄ ΠΎΡ‚ΠΊΠΎΠ»ΠΊΠΎΡ‚ΠΎ ΠΏΡ€ΠΈ локализация налСзията Π² лява хСмисфСра.The human brain is characterized by functional asymmetry including interhemispheric, cortical and subcortical interactions. Patients with acute ischemic stroke (AIS) in the left hemisphere and conducted thrombolytic therapy (IVT) have a two-fold greater likelihood of favorable clinical outcome of the third month compared with right hemispheric infarcts. Petticoats and left - sided location are predictors of significant improvement in neurological deficit 24 hours after IVT. On the other hand the association of male and right - sided location of stroke is associated with a greater likelihood of favorable clinical outcomes than women with the same location. In men it is associated with a better outcome than left-sided localization of the lesion
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