'Life is a state of Mind' - Fiction, Society and Trump

The article undertakes an allegorical double reading of Being There and Trump as instances of what we call socio-fiction. Crucially in this respect, reality and fiction are not two opposed realms. The two realms always interact in subtle ways, which is why cinema can be a resource for diagnostic social analysis. We first articulate a general commentary on the relationship between cinema and society, introducing the concept of ‘socio-fiction’. Secondly, we analyse Peter Sellers’ Being There, an interesting film focused on the relationship between reality and fiction. In this analysis, we elaborate on different ways of approaching fiction in a sociological prism. And finally, we discuss Trump as a fallout effect of Being There. After all, a film is not just an image of a reality, a shadow or appearance of a social fact; sometimes the reality itself seems to have become an appearance of an appearance, a shadow of a shadow

Impossible protest: noborders in Calais

Since the closure of the Red Cross refugee reception centre in Sangatte, undocumented migrants in Calais hoping to cross the border to Britain have been forced to take refuge in a number of squatted migrant camps, locally known by all as ‘the jungles.’ Unauthorised shanty-like residences built by the migrants themselves, living conditions in the camps are very poor. In June 2009, European ‘noborder’ activists set up a week-long protest camp in the area with the intention of confronting the authorities over their treatment of undocumented migrants. In this article, we analyse the June 2009 noborder camp as an instance of ‘immigrant protest.’ Drawing on ethnographic materials and Jacques Rancière's work on politics and aesthetics, we construct a typology of forms of border control through which to analyse the different ways in which the politics of the noborder camp were staged, performed and policed. Developing a critique of policing practices which threatened to make immigrant protest ‘impossible’, we highlight moments of protest which, through the affirmation of an ‘axiomatic’ equality, disrupted and disarticulated the borders between citizens and non-citizens, the political and non-political

MC38 colorectal tumor cell lines from two different sources display substantial differences in transcriptome, mutanome and neoantigen expression

IntroductionThe cell line MC38 is a commonly used murine model for colorectal carcinoma. It has a high mutational burden, is sensitive to immune checkpoint immunotherapy and endogenous CD8+ T cell responses against neoantigens have been reported. MethodsHere, we re-sequenced exomes and transcriptomes of MC38 cells from two different sources, namely Kerafast (originating from NCI/NIH, MC38-K) and the Leiden University Medical Center cell line collection (MC38-L), comparing the cell lines on the genomic and transcriptomic level and analyzing their recognition by CD8+ T cells with known neo-epitope specificity. ResultsThe data reveals a distinct structural composition of MC38-K and MC38-L cell line genomes and different ploidies. Further, the MC38-L cell line harbored about 1.3-fold more single nucleotide variations and small insertions and deletions than the MC38-K cell line. In addition, the observed mutational signatures differed; only 35.3% of the non-synonymous variants and 5.4% of the fusion gene events were shared. Transcript expression values of both cell lines correlated strongly (p = 0.919), but we found different pathways enriched in the genes that were differentially upregulated in the MC38-L or MC38-K cells, respectively. Our data show that previously described neoantigens in the MC38 model such as Rpl18(mut) and Adpgk(mut) were absent in the MC38-K cell line resulting that such neoantigen-specific CD8+ T cells recognizing and killing MC38-L cells did not recognize or kill MC38-K cells. ConclusionThis strongly indicates that at least two sub-cell lines of MC38 exist in the field and underlines the importance of meticulous tracking of investigated cell lines to obtain reproducible results, and for correct interpretation of the immunological data without artifacts. We present our analyses as a reference for researchers to select the appropriate sub-cell line for their own studies

Governing Uncertainty in a Secular Age: Rationalities of Violence, Theodicy and Torture

This article explores the problem of governing uncertainty in a secular age by focusing on the theological notion of ‘theodicy’ as the underlying rationale for the use of torture in the so-called ‘war on terror’. With God’s departure from the world, the problem of uncertainty acquires new salience as human beings can no longer explain tragic events as part of a transcendent order and must find immanent causes for the ‘evils’ that surround them. Taking a cue from Max Weber, I discuss how the problem of theodicy – how to reconcile the existence of God with the presence of evil in the world – does not disappear in the secular age but is mobilized through a Foucauldian biopolitical logic. Secular theodicy governs uncertainty through the production of economies of knowledge that rationalize processes of criminalization and securitization of entire groups and justify the use of violence. This process is particularly striking when analysing the use of torture in the so-called ‘war on terror’. Through a comparison with medieval practices and focusing on the cases of Guantanamo and Abu Ghraib, the article shows how secular torture is the product of a biopolitical theodicy aimed at governing uncertainty through the construction of the tortured as immanent evils who threaten our ‘good life’ and ‘deserve’ their treatment. Secular theodicy turns torture into an extreme form of governmentality of uncertainty in which the disciplining of conduct becomes the construction of subjectivities based on essentialist, stereotypical and racist – and for these very reasons, reassuring – economies of knowledge

Legal Paradigm Shifts and Their Impacts on the Socio-Spatial Exclusion of Asylum Seekers in Denmark

This chapter discusses the genesis of Denmark’s asylum accommodation system and recent legal and socio-spatial changes as a reaction to the increase of arrivals. By elucidating the structures and objectives of asylum accommodation, I present that the state’s further tightening of restrictive reception and accommodation policies significantly impacts the socio-spatial configurations of accommodations, refugees’ access to housing and their well-being. I discuss the links between the tensioning of laws, the reduction of living conditions and the (re-)constitution of large accommodations as means of socio-spatial exclusion. Applying the case of Denmark’s Hovedstaden Region (Capital Region), I finally argue that asylum accommodation is a central instrument of Denmark’s approaches to strategically isolate forced migrants and to deter them from migrating to Denmark

RetScreen Programı Kullanılarak Tekirdağ Namık Kemal Üniversitesi Ziraatbiyotek Binasına Uygulanabilecek Fotovoltaik Tasarımın Fizibilite Analizi

As a result of the rapid decrease in fossil fuels and increasing energy demand, countries have turned to alternative energy sources. Renewable resources, which are alternative to fossil resources and are environmentally friendly, are clean and inexhaustible energy resources. Solar energy is one of these alternative energy sources This study; With the RetScreen program, it is aimed to analyze the suitability of the system and observe its performance before the PV system is installed. Features affecting the performance of PV systems; It has been designed by considering factors such as the position of the panel, the angle of inclination, shading and panel type. Shadow analysis was performed with the Helioscope program. In the shadow analysis, firstly, the geographical location is defined and the determined parameters are entered into the system. Technical, energy and economic analysis of the 14 kW solar system for the Ziraatbiyotek building was made. The analysis was made in 2 different scenarios and the positive and negative aspects of the solar system to be installed in the building were revealed. The Ziraatbiyotek building, where the study was carried out, was established in the Naip District of the Süleymanpaşa district of Tekirdağ province. For the Ziraatbiyotek laboratory building, 60 panels of the GES power plant with an area of 405 m2 were used. The brand of the selected panel is Astronergy Solar and each has a power capacity of 240 W. The panel inclination is 300 and the azimuth angle is 00 in the RetScreen program. Polycrystalline was used as the panel type in two different scenarios. In the first scenario, emission reduction support was not included and the payback period of the system was 10.4 years, and in the other, $15 tCO2-1 and annual support of$142 were included and the payback period of the system was 9.8 years. According to the results obtained with the program, 20.1 Wh energy produced by the solar panel system decreased 9.5 tCO2 greenhouse gas emissions. It has been obtained that if a 14 kW solar energy system is installed in the Ziraatbiyotek building, approximately 40% of the annual electricity need will be met from solar energy. © Bu çalışma Tekirdağ Namık Kemal Üniversitesi tarafından