47 research outputs found

    New national and regional bryophyte records, 45

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    Standards and guidelines pertinent to the development of decommissioning criteria for sites contaminated with radioactive material

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    A review of existing health and safety standards and guidelines has been undertaken to assist in the development of criteria for the decontamination and decommissioning of property contaminated with radioactive material. During the early years of development of the nuclear program in the United States, a number of sites were used which became contaminated with radioactive material. Many of these sites are no longer useful for nuclear activities, and the U.S. DOE desires to develop criteria for the management of these sites for future uses. Radiation protection standards promulgated by ICRP, NCRP, and ANSI have been considered. Government regulations, from the Code of Federal Regulations and the legal codes of various states, as well as regulatory guidelines with specific application to decommissioning of nuclear facilities also have been reviewed. In addition, recommendations of other scientific organizations such as the National Academy of Sciences/National Research Council Advisory Committee on the Biological Effects of Ionizing Radiations and the United Nations Scientific Committee on the Effects of Atomic Radiation were considered. Finally, a few specific recommendations and discussions from current literature were included. 28 references

    Fourth Personnel Dosimetry Intercomparison Study

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    The fourth Personnel Dosimetry Intercomparison Study was held at the Oak Ridge National Laboratory's Dosimetry Applications Research Facility during March 15-23, 1978. The Health Physics Research Reactor (HPRR) used unshielded, with a 12-cm-thick Lucite shield, a 20-cm-thick concrete shield, or a 5-cm-thick steel and 15-cm-thick concrete shield, and provided four neutron and gamma-ray spectra. Then the dose was calculated based on the HPRR neutron spectra and dose conversion factors which had been determined previously for the four spectra. The results of these personnel dosimetry intercomparison studies reveal that estimates of dose equivalent vary over a wide range. The standard deviation of the mean of participants data for gamma measurements was in the range of 29 to 43%; for neutrons it was 57 to 188%. (PCS

    Two novel mutations in the vasopressin V2 receptor gene in patients with congenital nephrogenic diabetes insipidus

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    Families with congenital nephrogenic diabetes insipidus were analyzed with regard to mutations in the vasopressin V2 receptor gene. Family 1 shows an X-chromosomal recessive inheritance of the disease over 4 generations. A patient from this family was found to have a T-->A transversion at nucleotide 1095, predictive for a substitution of serine 167 (which is highly conserved among G-protein-coupled receptors), by threonine. Both the mutant and the normal allele were detected in the maternal genome. The patient's healthy brother was homozygous for the normal allele. The patient from family 2 showed a T-->C transition at nucleotide 727, predictive for a substitution of leucine 44 by proline. Analysis of the maternal genome revealed homozygosity for the normal allele. Thus a de novo mutation seems to have occurred. The nature and site of the mutation in family 2 suggest that it is responsible for the patient's disease
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