A dark energy multiverse

We present cosmic solutions corresponding to universes filled with dark and phantom energy, all having a negative cosmological constant. All such solutions contain infinite singularities, successively and equally distributed along time, which can be either big bang/crunchs or big rips singularities. Classicaly these solutions can be regarded as associated with multiverse scenarios, being those corresponding to phantom energy that may describe the current accelerating universe

Osteoporosis transitoria de la cadera: revisión de aspectos clínicos y terapéuticos a propósito de un caso

Presentamos el caso de una mujer de 17 años con osteoporosis transitoria de cadera (OTC). La OTC es una enfermedad infrecuente, difícil de etiquetar, que afecta a hombres sanos de mediana edad, y a mujeres en el tercer trimestre del embarzo. Su etiología todavía no está clara. Los principales signos clínicos son dolor en la cadera y cojera. La RM muestra en la cabeza y cuello femoral hipointensidad en las imágenes ponderadas en T1, e hiperintensidad en las imágenes ponderadas en T2. Se acepta que los cambios en la RM se producen por incremento de líquido en la cavidad medular de la cabeza femoral. Es importante el diagnóstico diferencial con otras enfermedades de la cadera. El propósito de esta publicación es aclarar los aspectos diagnósticos y terapéuticos de la OTC.A case of transient osteoporosis of the hips in a 17-year-old-woman is reported. Transient osteoporosis of the hip (TOH) is an uncommon but possibly underdiagnosed condition. The TOH affects previous healthy middle-age men, and women in the third trimester of pregnancy. Its etiology is still unclear. Pain in the hip area and limp are the main clinical signs. The MRI study shows low signal intensity on the Tl weighted images and limp signal intensity on the T2 weighted images in the femoral head and neck. It is generally accepted that the change in MRI is caused by an increase in fluid within the marrow cavities of the femoral head. Differential diagnosis of hip problems is required. The purpose of this report is to review the diagnostic and therapeutic aspects of TOH

The NALP3/Cryopyrin-Inflammasome Complex is Expressed in LPS-Induced Ocular Inflammation

In the inflammosome complex, NALP3 or NALP1 binds to ASC and activates caspase-1 which induces IL-1β. In murine LPS-induced ocular inflammation, the production of IL-1β is increased. We suggest that NALP3- or NALP1-inflammasome complex can be participating in the LPS-induced ocular inflammation. In this work, eye, brain, testis, heart, spleen, and lung were obtained from C3H/HeN mice treated with LPS for 3 to 48 hours, and the expression of NALP1b, NALP3, ASC, caspase-1, IL-1β, and IL-18 was determined. Infiltrated leukocytes producing IL-1β in the anterior chamber were found at 12-hour posttreatment. A high upregulated expression of NALP3, ASC, caspase-1, IL-1β, and IL-18 was found at the same time when infiltrated leukocytes were observed. NALP1b was not detected in the eye of treated mice. NALP3 was also overexpressed in heart and lung. These results suggest that NALP3-, but not NALP1-inflammosome complex, is participating in the murine LPS-induced ocular inflammation

Classical Euclidean wormhole solutions in Palatini f(R~)f(\tilde{R}) cosmology

We study the classical Euclidean wormholes in the context of extended theories of gravity. With no loss of generality, we use the dynamical equivalence between $f(\tilde{R})$ gravity and scalar-tensor theories to construct a point-like Lagrangian in the flat FRW space time. We first show the dynamical equivalence between Palatini $f(\tilde{R})$ gravity and the Brans-Dicke theory with self-interacting potential, and then show the dynamical equivalence between the Brans-Dicke theory with self-interacting potential and the minimally coupled O'Hanlon theory. We show the existence of new Euclidean wormhole solutions for this O'Hanlon theory and, for an special case, find out the corresponding form of $f(\tilde{R})$ having wormhole solution. For small values of the Ricci scalar, this $f(\tilde{R})$ is in agreement with the wormhole solution obtained for higher order gravity theory $\tilde{R}+\epsilon \tilde{R}^2,\epsilon<0$.Comment: 11 page

On the warp drive space-time

In this paper the problem of the quantum stability of the two-dimensional warp drive spacetime moving with an apparent faster than light velocity is considered. We regard as a maximum extension beyond the event horizon of that spacetime its embedding in a three-dimensional Minkowskian space with the topology of the corresponding Misner space. It is obtained that the interior of the spaceship bubble becomes then a multiply connected nonchronal region with closed timelike curves and that the most natural vacuum allows quantum fluctuations which do not induce any divergent behaviour of the re-normalized stress-energy tensor, even on the event (Cauchy) chronology horizon. In such a case, the horizon encloses closed timelike curves only at scales close to the Planck length, so that the warp drive satisfies the Ford's negative energy-time inequality. Also found is a connection between the superluminal two-dimensional warp drive space and two-dimensional gravitational kinks. This connection allows us to generalize the considered Alcubierre metric to a standard, nonstatic metric which is only describable on two different coordinate patchesComment: 7 pages, minor comment on chronology protection added, RevTex, to appear in Phys. Rev.

Slit Observations and Empirical Calculations for HII Regions

When analysing HII regions, a possible source of systematic error on empirically derived physical quantities is the limited size of the slit used for the observations. A grid of photoionization models was built through the Aangaba code varying the ionizing radiation spectrum emitted by a stellar cluster, as well as the gas abundance. The calculated line surface brightness was then used to simulate slit observations and to derive empirical parameters using the usual methods described in the literature. Depending on the fraction of the object covered by the slit, the parameters can be different from those obtained from observations of the whole object, an effect that is mainly dependent on the age of the ionizing stellar cluster. The low-ionization forbidden lines are more sensitive to the size of the area covered by the slit than the high-ionization forbidden lines or recombination lines. Regarding the temperature indicator T[OIII], the slit effects are small since this temperature is derived from [OIII] lines. On the other hand, for the abundance indicator R23, which depends also on the [OII] line, the slit effect is slightly higher. Therefore, the systematic error due to slit observations on the O abundance is low, being usually less than 10%, except for HII regions powered by stellar clusters with a relative low number of ionizing photons between 13.6 and 54.4 eV, which create a smaller O++ emitting volume. In this case, the systematic error on the empirical O abundance deduced from slit observations is more than 10% when the covered area is less than 50%.Comment: To be published in MNRAS, accepted in 09/09/2005, 17 pages and 6 figure

Quintessence and the first Doppler peak

By using a tracking quintessence model we obtain that the position of the first Doppler peak in the spectrum of CMB anisotropies only depends on the topology of the universe, $\Omega_k$, for any value of the ratio $\Omega_{\Lambda}/\Omega_M$, so that such a dependence is perfectly valid in the range suggested by supernova observations.Comment: 9 pages, LaTe

Histopathological characteristics of cutaneous lesions caused by Leishmania Viannia panamensis in Panama

Cutaneous leishmaniasis (CL) is an endemic disease in the Republic of Panama, caused by Leishmania (Viannia) parasites, whose most common clinical manifestation is the presence of ulcerated lesions on the skin. These lesions usually present a chronic inflammatory reaction, sometimes granulomatous, with the presence of lymphocytes, plasma cells and macrophages. This study describes the histopathological characteristics found in the skin lesions of patients with CL caused by Leishmania (V.) panamensis in Panama. We analyzed 49 skin biopsy samples from patients with clinical suspicion of CL, by molecular tests (PCR for subgenus Viannia and HSP-70) and by Hematoxylin-Eosin staining. Samples were characterized at the species level by PCR-HSP-70/RFLP. From the 49 samples studied, 46 (94%) were positive by PCR and were characterized as Leishmania (V.) panamensis. Of these, 48% were positive by Hematoxylin-Eosin staining with alterations being observed both, in the epidermis (85%) and in the dermis (100%) of skin biopsies. The inflammatory infiltrate was characterized according to histopathological patterns: lymphohistiocytic (50%), lymphoplasmacytic (61%) and granulomatous (46%) infiltration, being the combination of these patterns frequently found. The predominant histopathological characteristics observed in CL lesions caused by L. (V.) panamensis in Panama were: an intense inflammatory reaction in the dermis with a combination of lymphohistiocytic, lymphoplasmacytic and granulomatous presentation patterns and the presence of ulcers, acanthosis, exocytosis and spongiosis in the epidermis

Using membrane computing for obtaining homology groups of binary 2D digital images

Membrane Computing is a new paradigm inspired from cellular communication. Until now, P systems have been used in research areas like modeling chemical process, several ecosystems, etc. In this paper, we apply P systems to Computational Topology within the context of the Digital Image. We work with a variant of P systems called tissue-like P systems to calculate in a general maximally parallel manner the homology groups of 2D images. In fact, homology computation for binary pixel-based 2D digital images can be reduced to connected component labeling of white and black regions. Finally, we use a software called Tissue Simulator to show with some examples how these systems wor

Multi-band high resolution spectroscopy rules out the hot Jupiter BD+20 1790b - First data from the GIARPS Commissioning

Context. Stellar activity is currently challenging the detection of young planets via the radial velocity (RV) technique. Aims. We attempt to definitively discriminate the nature of the RV variations for the young active K5 star BD+20 1790, for which visible (VIS) RV measurements show divergent results on the existence of a substellar companion. Methods. We compare VIS data with high precision RVs in the near infrared (NIR) range by using the GIANO - B and IGRINS spectrographs. In addition, we present for the first time simultaneous VIS-NIR observations obtained with GIARPS (GIANO - B and HARPS - N) at Telescopio Nazionale Galileo (TNG). Orbital RVs are achromatic, so the RV amplitude does not change at different wavelengths, while stellar activity induces wavelength-dependent RV variations, which are significantly reduced in the NIR range with respect to the VIS. Results. The NIR radial velocity measurements from GIANO - B and IGRINS show an average amplitude of about one quarter with respect to previously published VIS data, as expected when the RV jitter is due to stellar activity. Coeval multi-band photometry surprisingly shows larger amplitudes in the NIR range, explainable with a mixture of cool and hot spots in the same active region. Conclusions. In this work, the claimed massive planet around BD+20 1790 is ruled out by our data. We exploited the crucial role of multi- wavelength spectroscopy when observing young active stars: thanks to facilities like GIARPS that provide simultaneous observations, this method can reach its maximum potential.Comment: 12 pages, 7 figure