573 research outputs found

    Hypothetical Reasoning via Provenance Abstraction

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    Data analytics often involves hypothetical reasoning: repeatedly modifying the data and observing the induced effect on the computation result of a data-centric application. Previous work has shown that fine-grained data provenance can help make such an analysis more efficient: instead of a costly re-execution of the underlying application, hypothetical scenarios are applied to a pre-computed provenance expression. However, storing provenance for complex queries and large-scale data leads to a significant overhead, which is often a barrier to the incorporation of provenance-based solutions. To this end, we present a framework that allows to reduce provenance size. Our approach is based on reducing the provenance granularity using user defined abstraction trees over the provenance variables; the granularity is based on the anticipated hypothetical scenarios. We formalize the tradeoff between provenance size and supported granularity of the hypothetical reasoning, and study the complexity of the resulting optimization problem, provide efficient algorithms for tractable cases and heuristics for others. We experimentally study the performance of our solution for various queries and abstraction trees. Our study shows that the algorithms generally lead to substantial speedup of hypothetical reasoning, with a reasonable loss of accuracy

    Structurally Tractable Uncertain Data

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    Many data management applications must deal with data which is uncertain, incomplete, or noisy. However, on existing uncertain data representations, we cannot tractably perform the important query evaluation tasks of determining query possibility, certainty, or probability: these problems are hard on arbitrary uncertain input instances. We thus ask whether we could restrict the structure of uncertain data so as to guarantee the tractability of exact query evaluation. We present our tractability results for tree and tree-like uncertain data, and a vision for probabilistic rule reasoning. We also study uncertainty about order, proposing a suitable representation, and study uncertain data conditioned by additional observations.Comment: 11 pages, 1 figure, 1 table. To appear in SIGMOD/PODS PhD Symposium 201

    Astrometric Control of the Inertiality of the Hipparcos Catalog

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    Based on the most complete list of the results of an individual comparison of the proper motions for stars of various programs common to the Hipparcos catalog, each of which is an independent realization of the inertial reference frame with regard to stellar proper motions, we redetermined the vector ω\omega of residual rotation of the ICRS system relative to the extragalactic reference frame. The equatorial components of this vector were found to be the following: ωx=+0.04±0.15\omega_x = +0.04\pm 0.15 mas yr1^{-1}, ωy=+0.18±0.12\omega_y = +0.18\pm 0.12 mas yr1^{-1}, and ωz=0.35±0.09\omega_z = -0.35\pm 0.09 mas yr1^{-1}.Comment: 8 pages, 1 figur

    On Multipartite Pure-State Entanglement

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    We show that pure states of multipartite quantum systems are multiseparable (i.e. give separable density matrices on tracing any party) if and only if they have a generalized Schmidt decomposition. Implications of this result for the quantification of multipartite pure-state entanglement are discussed. Further, as an application of the techniques used here, we show that any purification of a bipartite PPT bound entangled state is tri-inseparable, i.e. has none of its three bipartite partial traces separable.Comment: 8 Pages ReVTeX, 4 figures (eps); v2: Revised terminology, added two references and other minor changes; v3: Minor changes, added two references, added author's middle initial; v4: One footnote remove

    NMR Simulation of an Eight-State Quantum System

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    The propagation of excitation along a one-dimensional chain of atoms is simulated by means of NMR. The physical system used as an analog quantum computer is a nucleus of 133-Cs (spin 7/2) in a liquid crystalline matrix. The Hamiltonian of migration is simulated by using a special 7-frequency pulse, and the dynamics is monitored by following the transfer of population from one of the 8 spin energy levels to the other.Comment: 10 pages, 3 figure

    Magnetic Resonance

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    Contains research objectives and reports on three research projects

    Tunneling dynamics in relativistic and nonrelativistic wave equations

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    We obtain the solution of a relativistic wave equation and compare it with the solution of the Schroedinger equation for a source with a sharp onset and excitation frequencies below cut-off. A scaling of position and time reduces to a single case all the (below cut-off) nonrelativistic solutions, but no such simplification holds for the relativistic equation, so that qualitatively different ``shallow'' and ``deep'' tunneling regimes may be identified relativistically. The nonrelativistic forerunner at a position beyond the penetration length of the asymptotic stationary wave does not tunnel; nevertheless, it arrives at the traversal (semiclassical or B\"uttiker-Landauer) time "tau". The corresponding relativistic forerunner is more complex: it oscillates due to the interference between two saddle point contributions, and may be characterized by two times for the arrival of the maxima of lower and upper envelops. There is in addition an earlier relativistic forerunner, right after the causal front, which does tunnel. Within the penetration length, tunneling is more robust for the precursors of the relativistic equation

    AhR transcriptional activity in serum of Inuits across Greenlandic districts

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    <p>Abstract</p> <p>Background</p> <p>Human exposure to lipophilic persistent organic pollutants (POPs) including polychlorinated dibenzo-<it>p</it>-dioxins/furans (PCDDs/PCDFs), polychlorinated biphenyls (PCBs) and organochlorine pesticide is ubiquitous. The individual is exposed to a complex mixture of POPs being life-long beginning during critical developmental windows. Exposure to POPs elicits a number of species- and tissue-specific toxic responses, many of which involve the aryl hydrocarbon receptor (AhR). The aim of this study was to compare the actual level of integrated AhR transcriptional activity in the lipophilic serum fraction containing the actual POP mixture among Inuits from different districts in Greenland, and to evaluate whether the AhR transactivity is correlated to the bio-accumulated POPs and/or lifestyle factors.</p> <p>Methods</p> <p>The study included 357 serum samples from the Greenlandic districts: Nuuk and Sisimiut (South West Coast), Qaanaaq (North Coast) and Tasiilaq (East Coast). The bio-accumulated serum POPs were extracted by ethanol: hexane and clean-up on Florisil columns. Effects of the serum extract on the AhR transactivity was determined using the Hepa 1.12cR mouse hepatoma cell line carrying an AhR-luciferase reporter gene, and the data was evaluated for possible association to the serum levels of 14 PCB congeners, 10 organochlorine pesticide residues and/or lifestyle factors.</p> <p>Results</p> <p>In total 85% of the Inuit samples elicited agonistic AhR transactivity in a district dependent pattern. The median level of the AhR-TCDD equivalent (AhR-TEQ) of the separate genders was similar in the different districts. For the combined data the order of the median AhR-TEQ was Tasiilaq > Nuuk ≥ Sisimiut > Qaanaaq possibly being related to the different composition of POPs. In overall, the AhR transactivity was inversely correlated to the levels of sum POPs, age and/or intake of marine food.</p> <p>Conclusion</p> <p>i) We observed that the proportion of dioxin like (DL) compounds in the POP mixture was the dominating factor affecting the level of serum AhR transcriptional activity even at very high level of non DL-PCBs; ii) The inverse association between the integrated serum AhR transactivity and sum of POPs might be explained by the higher level of compounds antagonizing the AhR function probably due to selective POP bioaccumulation in the food chain.</p
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