122 research outputs found
Magnetism and effect of anisotropy with one dimensional monatomic chain of cobalt by a Monte Carlo simulation
The magnetic properties of the one dimensional (1D) monatomic chain of Co
reported in a previous experimental work are investigated by a classical Monte
Carlo simulation based on the anisotropic Heisenberg model. In our simulation,
the effect of the on-site uniaxial anisotropy, Ku, on each individual Co atom
and the nearest neighbour exchange interaction, J, are accounted for. The
normalized coercivity HC(T)/HC(TCL) is found to show a universal behaviour,
HC(T)/HC(TCL) = h0(e^{TB/T}-e) in the temperature interval, TCL < T < TBCal,
arising from the thermal activation effect. In the above expression, h0 is a
constant, TBCal is the blocking temperature determined by the calculation, and
TCL is the temperature above which the classical Monte Carlo simulation gives a
good description on the investigated system. The present simulation has
reproduced the experimental features, including the temperature dependent
coercivity, HC(T), and the angular dependence of the remanent magnetization,
MR(phi,theta), upon the relative orientation (phi,theta) of the applied field
H. In addition, the calculation reveals that the ferromagnetic-like open
hysteresis loop is a result of a slow dynamical process at T < TBCal. The
dependence of the dynamical TBCal on the field sweeping rate R, the on-site
anisotropy constant Ku, and the number of atoms in the atomic chain, N, has
been investigated in detail.Comment: 20 pages, 7 figures included, J Phys Condens Matter, In Pres
Ultra-thin Topological Insulator Bi2Se3 Nanoribbons Exfoliated by Atomic Force Microscopy
Ultra-thin topological insulator nanostructures, in which coupling between
top and bottom surface states takes place, are of great intellectual and
practical importance. Due to the weak Van der Waals interaction between
adjacent quintuple layers (QLs), the layered bismuth selenide (Bi2Se3), a
single Dirac-cone topological insulator with a large bulk gap, can be
exfoliated down to a few QLs. In this paper, we report the first controlled
mechanical exfoliation of Bi2Se3 nanoribbons (> 50 QLs) by an atomic force
microscope (AFM) tip down to a single QL. Microwave impedance microscopy is
employed to map out the local conductivity of such ultra-thin nanoribbons,
showing drastic difference in sheet resistance between 1~2 QLs and 4~5 QLs.
Transport measurement carried out on an exfoliated (\leq 5 QLs) Bi2Se3 device
shows non-metallic temperature dependence of resistance, in sharp contrast to
the metallic behavior seen in thick (> 50 QLs) ribbons. These AFM-exfoliated
thin nanoribbons afford interesting candidates for studying the transition from
quantum spin Hall surface to edge states
Tissue factor pathway inhibitor-2 was repressed by CpG hypermethylation through inhibition of KLF6 binding in highly invasive breast cancer cells
<p>Abstract</p> <p>Background</p> <p>Tissue factor pathway inhibitor-2 (TFPI-2) is a matrix-associated Kunitz inhibitor that inhibits plasmin and trypsin-mediated activation of zymogen matrix metalloproteinases involved in tumor progression, invasion and metastasis. Here, we have investigated the mechanism of DNA methylation on the repression of TFPI-2 in breast cancer cell lines.</p> <p>Results</p> <p>We found that both protein and mRNA of TFPI-2 could not be detected in highly invasive breast cancer cell line MDA-MB-435. To further investigate the mechanism of TFPI-2 repression in breast cancer cells, 1.5 Kb TFPI-2 promoter was cloned, and several genetic variations were detected, but the promoter luciferase activities were not affected by the point mutation in the promoter region and the phenomena was further supported by deleted mutation. Scan mutation and informatics analysis identified a potential KLF6 binding site in TFPI-2 promoter. It was revealed, by bisulfite modified sequence, that the CpG island in TFPI-2 promoter region was hypermethylated in MDA-MB-435. Finally, using EMSA and ChIP assay, we demonstrated that the CpG methylation in the binding site of KLF-6 diminished the binding of KLF6 to TFPI-2 promoter.</p> <p>Conclusion</p> <p>In this study, we found that the CpG islands in TFPI-2 promoter was hypermethylated in highly invasive breast cancer cell line, and DNA methylation in the entire promoter region caused TFPI-2 repression by inducing inactive chromatin structure and decreasing KLF6 binding to its DNA binding sequence.</p
Magnetic Doping and Kondo Effect in Bi2Se3 Nanoribbons
A simple surface band structure and a large bulk band gap have allowed Bi2Se3
to become a reference material for the newly discovered three-dimensional
topological insulators, which exhibit topologically-protected conducting
surface states that reside inside the bulk band gap. Studying topological
insulators such as Bi2Se3 in nanostructures is advantageous because of the high
surface-to-volume ratio, which enhances effects from the surface states;
recently reported Aharonov-Bohm oscillation in topological insulator
nanoribbons by some of us is a good example. Theoretically, introducing
magnetic impurities in topological insulators is predicted to open a small gap
in the surface states by breaking time-reversal symmetry. Here, we present
synthesis of magnetically-doped Bi2Se3 nanoribbons by vapor-liquid-solid growth
using magnetic metal thin films as catalysts. Although the doping concentration
is less than ~ 2%, low-temperature transport measurements of the Fe-doped
Bi2Se3 nanoribbon devices show a clear Kondo effect at temperatures below 30 K,
confirming the presence of magnetic impurities in the Bi2Se3 nanoribbons. The
capability to dope topological insulator nanostructures magnetically opens up
exciting opportunities for spintronics.Comment: 16 pages, 4 figure
Ambipolar Field Effect in Topological Insulator Nanoplates of (BixSb1-x)2Te3
Topological insulators represent a new state of quantum matter attractive to
both fundamental physics and technological applications such as spintronics and
quantum information processing. In a topological insulator, the bulk energy gap
is traversed by spin-momentum locked surface states forming an odd number of
surface bands that possesses unique electronic properties. However, transport
measurements have often been dominated by residual bulk carriers from crystal
defects or environmental doping which mask the topological surface
contribution. Here we demonstrate (BixSb1-x)2Te3 as a tunable topological
insulator system to manipulate bulk conductivity by varying the Bi/Sb
composition ratio. (BixSb1-x)2Te3 ternary compounds are confirmed as
topological insulators for the entire composition range by angle resolved
photoemission spectroscopy (ARPES) measurements and ab initio calculations.
Additionally, we observe a clear ambipolar gating effect similar to that
observed in graphene using nanoplates of (BixSb1-x)2Te3 in
field-effect-transistor (FET) devices. The manipulation of carrier type and
concentration in topological insulator nanostructures demonstrated in this
study paves the way for implementation of topological insulators in
nanoelectronics and spintronics.Comment: 7 pages, 4 figure
Rapid Surface Oxidation as a Source of Surface Degradation Factor for Bi2Se3
Bi2Se3 is a topological insulator with metallic surface states residing in a
large bulk bandgap. It is believed that Bi2Se3 gets additional n-type doping
after exposure to atmosphere, thereby reducing the relative contribution of
surface states in total conductivity. In this letter, transport measurements on
Bi2Se3 nanoribbons provide additional evidence of such environmental doping
process. Systematic surface composition analyses by X-ray photoelectron
spectroscopy reveal fast formation and continuous growth of native oxide on
Bi2Se3 under ambient conditions. In addition to n-type doping at the surface,
such surface oxidation is likely the material origin of the degradation of
topological surface states. Appropriate surface passivation or encapsulation
may be required to probe topological surface states of Bi2Se3 by transport
measurements
Aharonov-Bohm interference in topological insulator nanoribbons
Topological insulators represent novel phases of quantum matter with an
insulating bulk gap and gapless edges or surface states. The two-dimensional
topological insulator phase was predicted in HgTe quantum wells and confirmed
by transport measurements. Recently, Bi2Se3 and related materials have been
proposed as three-dimensional topological insulators with a single Dirac cone
on the surface and verified by angle-resolved photoemission spectroscopy
experiments. Here, we show unambiguous transport evidence of topological
surface states through periodic quantum interference effects in layered
single-crystalline Bi2Se3 nanoribbons. Pronounced Aharonov-Bohm oscillations in
the magnetoresistance clearly demonstrate the coverage of two-dimensional
electrons on the entire surface, as expected from the topological nature of the
surface states. The dominance of the primary h/e oscillation and its
temperature dependence demonstrate the robustness of these electronic states.
Our results suggest that topological insulator nanoribbons afford novel
promising materials for future spintronic devices at room temperature.Comment: 5 pages, 4 figures, RevTex forma
Binary Newton Calculation Method of Residual Stress Based on the Indentation Energy Difference Theory
Residual stress is a key parameter to evaluate the structural reliability of energy equipment. The indentation method has the characteristics of being nondestructive and easy to operate to calculate the residual stress of test materials, which has a broad application prospect in the field testing of energy equipment. However, because of the effect of preloading and data acquisition delay, the problem of indentation data fluctuation is prominent, and the indentation energy coefficient fitted by the traditional least square method is not consistent with the theoretical law, making it difficult to carry out stable calculations. In this paper, the Newton iteration formula of a binary nonlinear formula is derived based on the univariate Newton iteration formula, which is introduced into the data processing of residual stress, which increases the weight of the data in the stability stage and reduces the influence of the fluctuation data on the fitting results, so that the indentation energy coefficient is accurately calculated. Combined with the basic principle of indentation energy difference theory, the precise and efficient measurement of residual stress is realized
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